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We experimentally derived a unique one-to-one mapping between a range of selected bioactive chemicals and patterns of oscillations of the slime mould's extacellular electrical potential.

Emerging Technologies · Computer Science 2013-12-17 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

Decision-making is the process of selecting an action among alternatives, allowing biological and artificial systems to navigate complex environments and optimize behavior. While neural systems rely on neuron-based sensory processing and…

Biological Physics · Physics 2025-06-17 Lisa Schick , Emily Eichenlaub , Fabian Drexel , Alexander Mayer , Siyu Chen , Marcus Roper , Karen Alim

Physarum Polycephalum is a unicellular slime mold that has been intensely studied due to its ability to solve mazes, find shortest paths, generate Steiner trees, share knowledge, remember past events, and its applications to unconventional…

Biological Physics · Physics 2022-10-18 Sheryl Hsu , Laura P. Schaposnik

The amoeboid organism, the plasmodium of Physarum polycephalum, behaves on the basis of spatio-temporal pattern formation by local contraction-oscillators. This biological system can be regarded as a reaction-diffusion system which has…

patt-sol · Physics 2009-10-31 H. Yamada , T. Nakagaki , M. Ito

Plasmodium of Physarum polycephalum is a large cell, visible by unaided eye, which exhibits sophisticated patterns of foraging behaviour. The plasmodium's behaviour is well interpreted in terms of computation, where data are spatially…

Pattern Formation and Solitons · Physics 2012-06-25 Andrew Adamatzky

We report experimental laboratory studies on developing conductive pathways, or wires, using protoplasmic tubes of plasmodium of acellular slime mould Physarum polycephalum. Given two pins to be connected by a wire, we place a piece of…

Biological Physics · Physics 2013-09-17 Andrew Adamatzky

Many cells face search problems, such as finding food, mates or shelter, where their success depends on their search strategy. In contrast to other unicellular organisms, the slime mold Physarum polycephalum forms a giant network-shaped…

Biological Physics · Physics 2024-09-20 Lucas Tröger , Florian Goirand , Karen Alim

Slime mould Physarum polycephalum is large single cell with intriguingly smart behaviour. The slime mould shows outstanding abilities to adapt its protoplasmic network to varying environmental conditions. The slime mould can solve tasks of…

Emerging Technologies · Computer Science 2013-04-09 Andrew Adamatzky , Rachel Armstrong , Jeff Jones , Yukio-Pegio Gunji

Slime mould Physarum polycephalum builds up sophisticated networks to transport nutrients between distant part of its extended body. The slime mould's protoplasmic network is optimised for maximum coverage of nutrients yet minimum energy…

Pattern Formation and Solitons · Physics 2015-03-19 Andrew Adamatzky , Selim G. Akl

The Phychip project is a collaborative European research initiative to design and implement computation using the organism Physarum polycephalum; it is funded by the Seventh Framework Programme (FP7) by the European Commission within CORDIS…

Emerging Technologies · Computer Science 2014-11-26 James G. H. Whiting , Ben P. J. de Lacy Costello , Andrew Adamatzky

Purpose: Protoplasmic tubes of Physarum polycephalum, also know as Physarum Wires (PW), have been previously suggested as novel bio- electronic components. Until recently, practical examples of electronic circuits using PWs have been…

Emerging Technologies · Computer Science 2015-11-26 James G. H. Whiting , Richard Mayne , Nadine Moody , Ben de Lacy Costello , Andrew Adamatzky

Shortest path problems are a touchstone for evaluating the computing performance and functional range of novel computing substrates. Much has been published in recent years regarding the use of biocomputers to solve minimal path problems…

Emerging Technologies · Computer Science 2019-05-14 Richard Mayne

Plasmodium of acellular slime mould Physarum polycephalum is a very large eukaryotic microbe visible to the unaided eye. During its foraging behaviour the plasmodium spans sources of nutrients with a network of protoplasmic tubes. In this…

Adaptation and Self-Organizing Systems · Physics 2012-09-14 Andrew Adamatzky , Michael Lees , Peter M. A. Sloot

True slime mould Physarum polycephalum approximates a range of complex computations via growth and adaptation of its proto- plasmic transport network, stimulating a large body of recent research into how such a simple organism can perform…

Emerging Technologies · Computer Science 2015-03-12 Jeff Jones , Andrew Adamatzky

Slime mould of Physarum polycephalum is a large cell exhibiting rich spatial non-linear electrical characteristics. We exploit the electrical properties of the slime mould to implement logic gates using a flexible hardware platform designed…

Emerging Technologies · Computer Science 2016-07-11 Simon Harding , Jan Koutnik , Klaus Greff , Jurgen Schmidhuber , Andy Adamatzky

Very simple organisms, such as the single-celled amoeboid slime mould Physarum polycephalum possess no neural tissue yet, despite this, are known to exhibit complex biological and computational behaviour. Given such limited resources, can…

Emerging Technologies · Computer Science 2015-11-25 Jeff Jones

Complex distribution networks are pervasive in biology. Examples include nutrient transport in the slime mold \emph{Physarum polycephalum} as well as mammalian and plant venation. Adaptive rules are believed to guide development of these…

Adaptation and Self-Organizing Systems · Physics 2019-12-16 Henrik Ronellenfitsch , Eleni Katifori

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

Adaptation and Self-Organizing Systems · Physics 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

Multi-nucleated cells exist in all domains of life, ranging from animals, plants and fungi to single-celled organisms such as the slime mold Physarum polycephalum. The large cell size, in the case of Physarum reaching centimeters and more,…

Biological Physics · Physics 2026-05-12 Johnny Tong , Kaspar Wachinger , Fabian K. Henn , Nico Schramma , Siyu Chen , Karen Alim

We study the dynamics of a simple adaptive system in the presence of noise and periodic damping. The system is composed by two paths connecting a source and a sink, the dynamics is governed by equations that usually describe food search of…

Statistical Mechanics · Physics 2021-12-23 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi