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Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

To better describe the spread of a disease, we extend a discrete time stochastic SIR-type epidemic model of Tuckwell and Williams. We assume the dependence on time of the number of daily encounters and include a parameter to represent a…

Populations and Evolution · Quantitative Biology 2022-09-30 Mireia Besalú , Giulia Binotto

When an infection spreads in a community, an individual's probability of becoming infected depends on both her susceptibility and exposure to the contagion through contact with others. While one often has knowledge regarding an individual's…

Social and Information Networks · Computer Science 2017-12-05 Maggie Makar , John Guttag , Jenna Wiens

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

This paper presents a stochastic model motivated by the study of a virus-like evolving population with different mutation rates. This is a continuous time birth-death model: the birth processes are mutually-exciting Hawkes processes and the…

Probability · Mathematics 2026-03-10 Rahul Roy , Dharmaraja Selvamuthu , Paola Tardelli

The spread of certain diseases can be promoted, in some cases substantially, by prior infection with another disease. One example is that of HIV, whose immunosuppressant effects significantly increase the chances of infection with other…

Physics and Society · Physics 2014-08-04 M. E. J. Newman , C. R. Ferrario

Diseases and other contagion phenomena in nature and society can interact asymmetrically, such that one can benefit from the other, which in turn impairs the first, in analogy with predator-prey systems. Here, we consider two models for…

Physics and Society · Physics 2021-02-17 Paulo Cesar Ventura , Yamir Moreno , Francisco A. Rodrigues

Understanding disease dynamics is crucial for managing wildlife populations and assessing spillover risk to domestic animals and humans, but infection data on free-ranging animals are difficult to obtain. Because pathogen and parasite…

Quantitative Methods · Quantitative Biology 2025-09-26 Dongmin Kim , Théo Michelot , Katherine Mertes , Jared A. Stabach , John Fieberg

We consider exchangeable Markov multi-state survival processes -- temporal processes taking values over a state-space$\mathcal{S}$ with at least one absorbing failure state $\flat \in \mathcal{S}$ that satisfy natural invariance properties…

Methodology · Statistics 2018-10-26 Walter Dempsey

Performing model selection for coupled hidden Markov models (CHMMs) is highly challenging, owing to the large dimension of the hidden state process. Whilst in principle the hidden state process can be marginalized out via forward filtering,…

Methodology · Statistics 2021-05-26 Jake Carson , Trevelyan J. McKinley , Peter Neal , Simon E. F. Spencer

We introduce a model of parasite infection in a cell population, where cells can be infected, either at birth through maternal transmission, from a contact with the parasites reservoir, or because of the parasites released in the cell…

Probability · Mathematics 2021-11-10 Charline Smadi

Studies on how to model the interplay between diseases and behavioral responses (so-called coupled disease-behavior interaction) have attracted increasing attention. Owing to the lack of obvious clinical evidence of diseases, or the…

Physics and Society · Physics 2016-08-24 Hai-Feng Zhang , Jia-Rong Xie , Han-Shuang Chen , Can Liu , Michael Small

We suggest a novel approach to treating symbiotic relations between biological species or social entities. The main idea is the characterisation of symbiotic relations of coexisting species through their mutual influence on their respective…

Populations and Evolution · Quantitative Biology 2015-06-22 V. I. Yukalov , E. P. Yukalova , D. Sornette

Network ecology is a rising field of quantitative biology representing ecosystems as complex networks. A suitable example is parasite spreading: several parasites may be transmitted among their hosts through different mechanisms, each one…

Quantitative Methods · Quantitative Biology 2016-09-12 Massimo Stella , Cecilia S. Andreazzi , Sanja Selakovic , Alireza Goudarzi , Alberto Antonioni

Besides mimicking bio-chemical and multi-scale communication mechanisms, molecular communication forms a theoretical framework for virus infection processes. Towards this goal, aerosol and droplet transmission has recently been modeled as a…

Information Theory · Computer Science 2021-01-29 Peter Adam Hoeher , Martin Damrath , Sunasheer Bhattacharjee , Max Schurwanz

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

Food webs represent the set of consumer-resource interactions among a set of species that co-occur in a habitat, but most food web studies have omitted parasites and their interactions. Recent studies have provided conflicting evidence on…

Populations and Evolution · Quantitative Biology 2015-05-19 Abigail Z. Jacobs , Jennifer A. Dunne , Cristopher Moore , Aaron Clauset

The parameters of a discrete stationary Markov model are transition probabilities between states. Traditionally, data consist in sequences of observed states for a given number of individuals over the whole observation period. In such a…

Computation · Statistics 2012-04-30 Alberto Pasanisi , Shuai Fu , Nicolas Bousquet

Complex networks have played an important role in describing real complex systems since the end of the last century. Recently, research on real-world data sets reports intermittent interaction among social individuals. In this paper, we pay…

Social and Information Networks · Computer Science 2025-11-25 Ziyan Zeng , Minyu Feng , Jürgen Kurths