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In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The…

Neurons and Cognition · Quantitative Biology 2023-08-16 Bhanu Sharma , Spandan Kumar , Subhendu Ghosh , Vikram Singh

We report a spectrum of exotic frequency-locked states in a ring of phase oscillators with pure three-body interactions. For identical oscillators, the system hosts a vast multiplicity of stable quantized frequency-locked states without…

Pattern Formation and Solitons · Physics 2025-12-23 Jinfeng Liang , Shanshan Zhu , Yang Li , Qionglin Dai , Haihong Li , Junzhong Yang

A recurring motif in gene regulatory networks is transcription factors (TFs) that regulate each other, and then bind to overlapping sites on DNA, where they interact and synergistically control transcription of a target gene. Here, we…

Molecular Networks · Quantitative Biology 2013-03-07 Sahand Hormoz

We study phase synchronization for a ratchet system. We consider the deterministic dynamics of a particle in a tilted ratchet potential with an external periodic forcing, in the overdamped case. The ratchet potential has to be tilted in…

Other Condensed Matter · Physics 2009-11-11 Fernando R. Alatriste , José L. Mateos

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

Cell Behavior · Quantitative Biology 2019-07-08 Shou-Wen Wang , Lei-Han Tang

Electroencephalographic neurofeedback (EEG-NF) has been proposed as a promising technique to modulate brain activity through real-time EEG-based feedback. Alpha neurofeedback in particular is believed to induce rapid self-regulation of…

Neurons and Cognition · Quantitative Biology 2025-09-15 Jacob Maaz , Laurent Waroquier , Alexandra Dia , Véronique Paban , Arnaud Rey

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Optimization and Control · Mathematics 2024-09-23 Roman Chertovskih , Nikolay Pogodaev , Maxim Staritsyn , Joaquim Da Silva Sewane , Antonio Pedro Aguiar

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

Neurons and Cognition · Quantitative Biology 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko

Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

Biological Physics · Physics 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

Other Quantitative Biology · Quantitative Biology 2016-03-08 Erich W. Schmid

Multiple organs in a living system respond to environmental changes, and the signals from the organs regulate the physiological environment. Inspired by this biological feedback, we propose a simple autonomous system of active rotators to…

Statistical Mechanics · Physics 2020-03-02 Taegeun Song , Heetae Kim , Seung-Woo Son , Junghyo Jo

In the paper we investigate a mathematical model describing the growth of tumor in the presence of immune response of a host organism. The dynamics of tumor and immune cells is based on the generic Michaelis-Menten kinetics depicting…

Biological Physics · Physics 2009-11-13 Alessandro Fiasconaro , Anna Ochab-Marcinek , Bernardo Spagnolo , Ewa Gudowska-Nowak

Ultrafast perturbations offer a unique tool to manipulate correlated systems due to their ability to promote transient behaviors with no equilibrium counterpart. A widely employed strategy is the excitation of coherent optical phonons, as…

Superconductivity · Physics 2018-01-24 Michael Schütt , Peter P. Orth , Alex Levchenko , Rafael M. Fernandes

Gene expression is a noisy process that leads to regime shift between alternative steady states among individual living cells, inducing phenotypic variability. The effects of white noise on the regime shift in bistable systems have been…

Molecular Networks · Quantitative Biology 2017-08-23 Yogita Sharma , Partha Sharathi Dutta

Many natural and industrial turbulent flows are subjected to time-dependent boundary conditions. Despite being ubiquitous, the influence of temporal modulations (with frequency $f$) on global transport properties has hardly been studied.…

Fluid Dynamics · Physics 2020-10-14 Rui Yang , Kai Leong Chong , Qi Wang , Roberto Verzicco , Olga Shishkina , Detlef Lohse

The phenomenon of synchronization, where entities exhibit stable oscillations with aligned frequencies and phases, has been detected in diverse areas of natural science. It plays a crucial role in achieving frequency locking in multiple…

Quantum Physics · Physics 2025-06-24 Tong Liu , Laura García-Álvarez , Giovanna Tancredi

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

Brain dynamics can exhibit narrow-band nonlinear oscillations and multistability. For a subset of disorders of consciousness and motor control, we hypothesize that some symptoms originate from the inability to spontaneously transition from…

Neurons and Cognition · Quantitative Biology 2020-06-24 Ian D. Jordan , Il Memming Park