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We develop a physiological model of granulopoiesis which includes explicit modelling of the kinetics of the cytokine granulocyte colony-stimulating factor (G-CSF) incorporating both the freely circulating concentration and the concentration…

Cell Behavior · Quantitative Biology 2016-11-17 Morgan Craig , Antony R Humphries , Michael C Mackey

We propose a computational model of neuron, called firing cell (FC), properties of which cover such phenomena as attenuation of receptors for external stimuli, delay and decay of postsynaptic potentials, modification of internal weights due…

Neural and Evolutionary Computing · Computer Science 2017-04-24 Jacek Bialowas , Beata Grzyb , Pawel Poszumski

Neurons in the brain behave as a network of coupled nonlinear oscillators processing information by rhythmic activity and interaction. Several technological approaches have been proposed that might enable mimicking the complex information…

Applied Physics · Physics 2018-11-07 M. Vogel , B. Zimmermann , J. Wild , F. Schwarzhuber , C. Mewes , T. Mewes , J. Zweck , C. H. Back

The onset of collective behavior in a population of globally coupled oscillators with randomly distributed frequencies is studied for phase dynamical models with arbitrary coupling. The population is described by a Fokker-Planck equation…

adap-org · Physics 2009-10-28 John David Crawford

For studying how dynamical responses to external stimuli depend on the synaptic-coupling type, we consider two types of excitatory and inhibitory synchronization (i.e., synchronization via synaptic excitation and inhibition) in complex…

Neurons and Cognition · Quantitative Biology 2016-11-29 Sang-Yoon Kim , Woochang Lim

Recently, the synchronization of coupled quantum oscillators has attracted a great deal of interest. Synchronization requires driven constituents, and in such systems, the coupling can be designed to be nonreciprocal. Nonreciprocally…

Quantum Physics · Physics 2025-07-29 Tobias Kehrer , Christoph Bruder

The dynamics of an oscillator driven by both low- and high- frequency external signals is studied. It is shown that both two- and three-frequency resonances arise due to a nonlinear interaction of these harmonic forces. Conditions which…

Chaotic Dynamics · Physics 2017-03-30 Anastasiia Y. Nimets , Klaus Schuenemann , Dmytro M. Vavriv

The influence of external fluctuations in phase separation processes is analysed. These fluctuations arise from random variations of an external control parameter. A linear stability analysis of the homogeneous state shows that phase…

Condensed Matter · Physics 2009-10-30 J. Garcia-Ojalvo , A. M. Lacasta , J. M. Sancho , R. Toral

We study the joint effect of thermal bath fluctuations and an external noise tuning activity of cytotoxic cells on the triggered immune response in a growing cancerous tissue. The immune response is assumed to be primarily mediated by…

Populations and Evolution · Quantitative Biology 2015-06-26 Anna Ochab-Marcinek , Ewa Gudowska-Nowak

We present a phenomenological reduced-order model to capture the transition to thermoacoustic instability in turbulent combustors. The model is based on the framework of synchronization and considers the acoustic field and the unsteady heat…

Adaptation and Self-Organizing Systems · Physics 2022-06-14 Yue Weng , Vishnu R. Unni , R. I. Sujith , Abhishek Saha

Oscillations are a hallmark of neural population activity in various brain regions with a spectrum covering a wide range of frequencies. Within this spectrum gamma oscillations have received particular attention due to their ubiquitous…

Neurons and Cognition · Quantitative Biology 2020-01-22 Hongjie Bi , Marco Segneri , Matteo di Volo , Alessandro Torcini

Transforming Growth Factor-beta (TGF-beta) signalling is an important regulator of cellular growth and differentiation. The principal intracellular mediators of TGF-beta signalling are the Smad proteins, which upon TGF-beta stimulation…

Molecular Networks · Quantitative Biology 2007-05-23 D. C. Clarke , M. D. Betterton , X. Liu

We present a theoretical study of a system with competing short-range ferromagnetic attraction and a long-range anti-ferromagnetic repulsion, in the presence of a uniform external magnetic field. The interplay between these interactions, at…

Statistical Mechanics · Physics 2009-04-04 T. Ferraro , A. Coniglio , M. Zannetti

A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes are taken into…

Biological Physics · Physics 2021-04-28 Vitaly L. Galinsky , Lawrence R. Frank

Mechanical signaling plays a key role in biological processes like embryo development and cancer growth. One prominent way to probe mechanical properties of tissues is to study their response to externally applied forces. Using a…

Soft Condensed Matter · Physics 2017-04-18 D. A. Matoz-Fernandez , Elisabeth Agoritsas , Jean-Louis Barrat , Eric Bertin , Kirsten Martens

Timing is essential for many cellular processes, from cellular responses to external stimuli to the cell cycle and circadian clocks. Many of these processes are based on gene expression. For example, an activated gene may be required to…

Molecular Networks · Quantitative Biology 2017-02-24 Alma Dal Co , Marco Cosentino Lagomarsino , Michele Caselle , Matteo Osella

Amoeboid cell migration is characterized by frequent changes of the direction of motion and resembles a persistent random walk on long time scales. Although it is well known that cell migration is typically driven by the actin cytoskeleton,…

Biological Physics · Physics 2021-06-09 Nicolas Ecker , Karsten Kruse

We report experimental evidence of the route to spatiotemporal chaos in a large 1D-array of hotspots in a thermoconvective system. Increasing the driving force, a stationary cellular pattern becomes unstable towards a mixed pattern of…

Chaotic Dynamics · Physics 2011-03-10 M. A. Miranda , J. Burguete

We consider a rotator whose equation of motion for the angle $\theta$ consists of the zeroth and first Fourier modes. Numerical analysis based on the trailing of saddle-node bifurcations is used to locate the n:1 Arnold tongues where…

Chaotic Dynamics · Physics 2008-11-15 David Garcia-Alvarez , Aneta Stefanovska , Peter V. E. McClintock

A general approach to consider spatially extended stochastic systems with correlations between additive and multiplicative noises subject to nonlinear damping is developed. Within modified cumulant expansion method, we derive an effective…

Statistical Mechanics · Physics 2009-11-10 A. I. Olemskoi , D. O. Kharchenko , I. A. Knyaz'
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