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The mechanism of phase synchronization between uncoupled limit-cycle oscillators induced by common external impulsive forcing is analyzed. By reducing the dynamics of the oscillator to a random phase map, it is shown that phase…
The rates of activated processes, such as escape from a metastable state and nucleation, are exponentially sensitive to an externally applied field. We describe how this applies to modulation by high-frequency fields and illustrate it with…
Recurrently coupled networks of inhibitory neurons robustly generate oscillations in the gamma band. Nonetheless, the corresponding Wilson-Cowan type firing rate equation for such an inhibitory population does not generate such oscillations…
The coupled electron-nuclear spin system in an InGaAs semiconductor as testbed of nonlinear dynamics can develop auto-oscillations, resembling time-crystalline behavior, when continuously excited by a circularly polarized laser. We expose…
We continue our study of a field formalism for large sets of interacting neurons, together with their connectivity functions. Expanding upon the foundation laid in ([9]), we formulate an effective formalism for the connectivity field in the…
We investigate both theoretically and numerically the dynamics of Out-of-Time-Ordered Correlators (OTOCs) in quantum resonance condition for a kicked rotor model. We employ various operators to construct OTOCs in order to thoroughly…
Robust oscillations play crucial roles in a wide variety of biological processes and are often generated by deterministic mechanisms. However, stochastic fluctuations often generate complex perturbations of these deterministic oscillations,…
We investigate neuronal excitability in the Hodgkin-Huxley model under temporal interference (TI) stimulation in a previously unexplored sub-Hz resonant regime and uncover a striking nonlinear response that we term 'multi-tongue frequency…
Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…
Noise caused by fluctuations at the molecular level is a fundamental part of intracellular processes. While the response of biological systems to noise has been studied extensively, there has been limited understanding of how to exploit it…
Phenotypic noise underpins homeostasis and fitness of individual cells. Yet, the extent to which noise shapes cell-to-population properties in microbial active matter remains poorly understood. By quantifying variability in confluent…
Background The epidermal growth factor receptor (EGFR) is frequently overexpressed in many cancers, including non-small cell lung cancer (NSCLC). In silcio modeling is considered to be an increasingly promising tool to add useful insights…
Genes are connected in complex networks of interactions where often the product of one gene is a transcription factor that alters the expression of another. Many of these networks are based on a few fundamental motifs leading to switches…
Many systems are modulated by unknown slow processes. This hinders analysis in highly non-linear systems, such as excitable systems. We show that for such systems, if the input matches the sparse `spiky' nature of the output, the spiking…
We consider a phenotype-structured reaction-diffusion model of avascular glioma growth. The model describes the interaction dynamics between tumour cells and oxygen, and takes into account anisotropic cell movement and oxygen diffusion…
We consider a one-dimensional directional array of diffusively coupled oscillators. They are perturbed by the injection of a small additive noise, typically orders of magnitude smaller than the oscillation amplitude, and the system is…
We introduce an extension to the standard reduction of oscillatory systems to a single phase variable. The standard reduction is often insufficient, particularly when the oscillations have variable amplitude and the magnitude of each…
A model is proposed to study the process of hypoxia-induced angiogenesis in cancer cells. The model accounts for the role played by the vascular endothelial growth factor (VEGF)-A in regulating the oxygen intake. VEGF-A is dynamically…
Cellular responses in the single cells are known to be highly heterogeneous and individualistic due to the strong influence by extrinsic and intrinsic noise. Here, we are concerned about how to model the extrinsic noise-induced…
A system of two enzymes mechanically coupled to each other in a viscous medium was recently studied, and conditions for obtaining synchronization and an enhanced average rate of the thermally-activated catalytic reactions of the enzymes…