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The breakage of a polymer chain of segments, coupled by anharmonic bonds with applied constant external tensile force is studied by means of Molecular Dynamics simulation. We show that the mean life time of the chain becomes progressively…

Soft Condensed Matter · Physics 2015-05-27 J. Paturej , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

The protein folding problem is stated and a list of properties that do not depend upon specific molecules is compiled and analyzed. The relationship of this analysis to future simulations is emphasized. The choice of power and time as…

Biological Physics · Physics 2017-09-26 Walter A. Simmons

In this work, we examine the whip dynamics in a freely falling chain. We consider an inextensible chain with free ends in the presence of gravity hanging from a fixed pulley. If the configuration is unbalanced, the chain begins to…

Classical Physics · Physics 2022-07-21 Tianyi Guo , Xiaoyu Zheng , Peter Palffy-Muhoray

We have used kinetic Monte Carlo simulations to study the kinetics of unfolding of cross-linked polymer chains under mechanical loading. As the ends of a chain are pulled apart, the force transmitted by each crosslink increases until it…

Biological Physics · Physics 2009-11-10 Kilho Eom , Dmitrii E Makarov , Gregory J. Rodin

Lifetimes of bound states of protein complexes or biomolecule folded states typically decrease when subject to mechanical force. However, a plethora of biological systems exhibit the counter-intuitive phenomenon of catch bonding, where…

Biomolecules · Quantitative Biology 2016-01-12 Shaon Chakrabarti , Michael Hinczewski , D. Thirumalai

This paper investigates the motion of falling leaves through modeling using papers and the corresponding data collected from more than four thousands experiments. Two series of experiments were designed in order to study the relationship…

Popular Physics · Physics 2011-11-11 Pedram Razavi

We introduce a novel, two-mass system that slides up an inclined plane while its center of mass moves down. The system consists of two identical masses connected by an ideal string symmetrically placed over a corner-shaped support. This…

Popular Physics · Physics 2016-11-23 Constantin Rasinariu , Asim Gangopadhyaya

A microscopic theory of the free energy barriers and folding routes for minimally frustrated proteins is presented, greatly expanding on the presentation of the variational approach outlined previously [J. J. Portman, S. Takada, P. G.…

Soft Condensed Matter · Physics 2009-10-31 John J. Portman , Shoji Takada , Peter G. Wolynes

This paper deals with the theoretical and numerical analysis of dynamic fracture of dissimilar chain consisting of masses lined by springs. Such a structure exhibits quite different dynamic properties in comparison with a symmetrical…

Soft Condensed Matter · Physics 2017-09-11 Nikolai Gorbushin , Gennady Mishuris

A model system inspired by recent experiments on the dynamics of a folded protein under the influence of a sinusoidal force is investigated and found to replicate many of the response characteristics of such a system. The essence of the…

Soft Condensed Matter · Physics 2015-09-30 Craig Fogle , Joseph Rudnick , David Jasnow

In spite of decades of research, much remains to be discovered about folding: the detailed structure of the initial (unfolded) state, vestigial folding instructions remaining only in the unfolded state, the interaction of the molecule with…

Biological Physics · Physics 2018-11-26 Walter A. Simmons

We study the friction between a flat solid surface where polymer chains have been end-grafted and a cross-linked elastomer at low sliding velocity. The contribution of isolated grafted chains' penetration in the sliding elastomer has been…

Soft Condensed Matter · Physics 2015-06-24 Thomas Vilmin , Elie Raphael

In network systems, a local perturbation can amplify as it propagates, potentially leading to a large-scale cascading failure. Here we derive a continuous model to advance our understanding of cascading failures in power-grid networks. The…

Physics and Society · Physics 2017-12-18 Yang Yang , Adilson E. Motter

Folding kinetics of a lattice model of protein is studied. It uses the Random Energy Model for the intrachain couplings and a temperature dependent free energy of solvation derived from a realistic hydration model of apolar solutes. The…

Statistical Mechanics · Physics 2008-11-06 Olivier Collet

We propose a simple friction model for isolated polymer chains on a solid substrate. The chains are pulled at constant velocity by one end, the other end can be trapped on the solid substrate on localised sites. We focus on the energy…

Soft Condensed Matter · Physics 2009-10-31 T. Charitat , J. F. Joanny

In recent years the chain fountain became prominent for its counter-intuitive fascinating physical behavior. Most widely known is the experiment in which a long chain leaves an elevated beaker like a fountain and falls to the ground under…

Classical Physics · Physics 2020-09-02 Johannes Mayet , Friedrich Pfeiffer

We adopt the point of view that analysis of the stability of the protein folding process is central to understanding the underlying physics of folding. Stability of the folding process means that many perturbations do not disrupt the…

Biological Physics · Physics 2011-12-30 Walter Simmons , Joel L. Weiner

A polymer chain tethered to a surface may be compact or extended, adsorbed or desorbed, depending on interactions with the surface and the surrounding solvent. This leads to a rich phase diagram with a variety of transitions. To investigate…

Soft Condensed Matter · Physics 2009-11-13 Jutta Luettmer-Strathmann , Federica Rampf , Wolfgang Paul , Kurt Binder

Fragmentation can be observed in nature and in everyday life on a wide range of length scales and for all kinds of technical applications. Most studies on dynamic failure focus on the behaviour of bulk systems in one, two and three…

Soft Condensed Matter · Physics 2015-10-02 Falk K. Wittel , Ferenc Kun , Hans J. Herrmann , Bernd H. Kröplin

The motion of weights attached to a chain or string moving on a frictionless pulley is a classic problem of introductory physics used to understand the relationship between force and acceleration. Here, we consider the dynamics of the chain…

Soft Condensed Matter · Physics 2016-06-30 Pierre-Thomas Brun , Basile Audoly , Alain Goriely , Dominic Vella