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We present an experiment in which a horizontal quasi-2D granular system with a fixed neighbor network is cyclically compressed and decompressed over 1000 cycles. We remove basal friction by floating the particles on a thin air cushion, so…

Soft Condensed Matter · Physics 2017-08-02 Jonathan E. Kollmer , Karen E. Daniels

We propose a general theory to describe the distribution of protein-folding transition paths. We show that transition paths follow a predictable sequence of high-free-energy transient states that are separated by free-energy barriers. Each…

Biomolecules · Quantitative Biology 2016-09-21 William M. Jacobs , Eugene I. Shakhnovich

We consider the rupture dynamics of a homopolymer chain pulled at one end at a constant loading rate r. Compared to single bond breaking, the existence of the chain introduces two new aspects into rupture dynamics: the non-Markovian aspect…

Soft Condensed Matter · Physics 2009-10-29 S. Fugmann , I. M. Sokolov

We theoretically investigate the kinetics of the folding transition of a single semiflexible polymer. In the folding transition, the growth rate decrease with an increase in the number of monomers in a collapsed domain, suggesting that the…

Soft Condensed Matter · Physics 2009-11-13 Natsuhiko Yoshinaga

Dried droplets of polymer solutions of different molecular weights and concentrations leave various types of 'coffee-ring' patterns. These patterns are consequence of contact line motion. We have observed for very low molecular weight the…

Soft Condensed Matter · Physics 2014-03-20 Nupur Biswas , Alokmay Datta

The dynamics of viscous thin-film particle-laden flows down inclined surfaces are commonly modeled with one of two approaches: a diffusive flux model or a suspension balance model. The diffusive flux model assumes that the particles migrate…

Many protein systems fold in a two-state manner. Random models, however, rarely display two-state kinetics and thus such behavior should not be accepted as a default. To date, many theories for the prevalence of two-state kinetics have been…

Biological Physics · Physics 2015-06-15 Thomas J. Lane , Christian R. Schwantes , Kyle A. Beauchamp , Vijay S. Pande

We consider a stiff polymer chain in poor solvent and apply a force at one end of the chain. We find that by varying the stiffness parameter, polymer undergoes a transition from the globule state to the folded like state. The conformation…

Soft Condensed Matter · Physics 2015-05-13 Sanjay Kumar , Debaprasad Giri

We exactly solve a model of a heterogeneous chain of overdamped, harmonically coupled particles with momentum-conserving dissipation. Despite being governed by a non-symmetric drift operator, the system admits an analytical diagonalization…

Statistical Mechanics · Physics 2026-05-26 Rupayan Saha , Matthias Krüger

We investigate the dynamics of a single semiflexible filament, under the action of a compressing force, using numerical simulations and scaling arguments. The force is applied along the end to end vector at one extremity of the filament,…

Soft Condensed Matter · Physics 2009-11-07 P. Ranjith , P. B. Sunil Kumar

In this paper we study the phenomenon of kinetic partitioning when a polypeptide chain has two ground state conformations one of which is more kinetically reachable than the other. This question is relevant to understand the phenomenology…

Condensed Matter · Physics 2007-05-23 V. I. Abkevich , A. M. Gutin , E. I. Shakhnovich

The rupture of a polymer chain maintained at temperature $T$ under fixed tension is prototypical to a wide array of systems failing under constant external strain and random perturbations. Past research focused on analytic and numerical…

Soft Condensed Matter · Physics 2021-03-03 Harish Charan , Alex Hansen , H. G. E. Hentschel , Itamar Procaccia

Proteins fold using a two-state or multi-state kinetic mechanisms, but up to now there isn't a first-principle model to explain this different behaviour. We exploit the network properties of protein structures by introducing novel…

Molecular Networks · Quantitative Biology 2015-12-04 Giulia Menichetti , Piero Fariselli , Daniel Remondini

We explore the malleability of ultra-small metal nanoparticles by means of ab initio calculations. It is revealed that, when strained, such nanoparticles exhibit complex behavior, including bifurcation between slow and fast quakes of their…

Mesoscale and Nanoscale Physics · Physics 2017-11-06 Alireza Saffarzadeh , George Kirczenow

A conceptual difficulty in the Hooke's-law description of ideal Gaussian polymer-chain elasticity is sometimes apparent in analyses of experimental data or in physical models designed to simulate the behavior of biopolymers. The problem,…

Biological Physics · Physics 2009-09-25 Richard M. Neumann

We employ simulations of model proteins to study folding on rugged energy landscapes. We construct ``first-passage'' networks as the system transitions from unfolded to native states. The nodes and bonds in these networks correspond to…

Soft Condensed Matter · Physics 2015-05-13 Gregg Lois , J. Blawzdziewicz , Corey S. O'Hern

Dynamics of a dry-rebounding drop was studied experimentally, numerically, and theoretically. Experimental results were reproduced by our computational fluid dynamics simulations, from which time series of kinetic energy, potential energy,…

Fluid Dynamics · Physics 2018-07-03 Akio Nishimura , Henry Weller , Hirokazu Maruoka , Masao Takayanagi , Hideharu Ushiki

The non-equilibrium structural and dynamical properties of a flexible polymer tethered to a reflecting wall and subject to oscillatory linear flow are studied by numerical simulations. Polymer is confined in two dimensions and is modeled as…

Soft Condensed Matter · Physics 2024-07-30 A. Lamura

The dynamical chaos in Lennard-Jones toy models of heteropolymers is studied by molecular dynamics simulations. It is shown that two nearby trajectories quickly diverge from each other if the heteropolymer corresponds to a random sequence.…

Statistical Mechanics · Physics 2009-10-31 Mai Suan Li , Marek Cieplak , Nazar Sushko

Dynamical frictional phenomena are studied theoretically in a two-chain model with incommensurate structure. A perturbation theory with respect to the interchain interaction reveals the contributions from phonons excited in each chain to…

Statistical Mechanics · Physics 2009-10-30 Takaaki Kawaguchi , Hiroshi Matsukawa