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In this work, we study in detail the distribution of stochastic forces generated by the molecular motors activity, in the actin cortex of pre-muscular cells. By combining active and passive rheology experiments, performed on the same…

Biological Physics · Physics 2019-12-10 P. Bohec , J. Tailleur , F. van Wijland , A. Richert , F. Gallet

A novel mechanism of reaction-induced active molecular motion, not involving any kind of self-propulsion, is proposed and analyzed. Because of the momentum exchange with the surrounding solvent, conformational transitions in…

Soft Condensed Matter · Physics 2023-04-19 Hiroyuki Kitahata , Alexander S. Mikhailov

Cells generally convert nutrient resources to useful products via energy transduction. Accordingly, the thermodynamic efficiency of this conversion process is one of the most essential characteristics of living organisms. However, although…

Biological Physics · Physics 2016-05-04 Yusuke Himeoka , Kunihiko Kaneko

The collective motion of microorganisms and microrobots can be used for particle delivery, especially when guided by external magnetic fields, phototaxis, or chemotaxis. This cargo transport is enhanced significantly by hydrodynamic…

Soft Condensed Matter · Physics 2025-09-30 Maggie Liu , Arnold J. T. M. Mathijssen

The bacterium E. coli maneuvers itself to regions with high chemoattractant concentrations by performing two stereotypical moves: `runs', in which it moves in near straight lines, and `tumbles', in which it does not advance but changes…

Cell Behavior · Quantitative Biology 2007-11-29 Yariv Kafri , Rava Azeredo da Silveira

Organisms have evolved a variety of mechanisms to cope with the unpredictability of environmental conditions, and yet mainstream models of metabolic regulation are typically based on strict optimality principles that do not account for…

Molecular Networks · Quantitative Biology 2020-07-08 David S. Tourigny

Energy considerations can significantly affect the behavior of a population of energy-consuming agents with limited energy budgets, for instance, in the movement process of people in a city. We consider a population of interacting agents…

Disordered Systems and Neural Networks · Physics 2024-11-13 Mohsen Ghasemi Nezhadhaghighi , Abolfazl Ramezanpour

{\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles…

Statistical Mechanics · Physics 2013-09-05 M. Paoluzzi , R. Di Leonardo , L. Angelani

Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental…

Soft Condensed Matter · Physics 2024-11-20 Steven J. Chisolm , Emily Guo , Vignesh Subramaniam , Kyle D. Schulze , Thomas E. Angelini

Heterogeneous systems of active matter exhibit a range of complex emergent dynamical patterns. In particular, it is difficult to predict the properties of the mixed system based on its constituents. These considerations are particularly…

Soft Condensed Matter · Physics 2021-04-07 Shlomit Peled , Shawn D. Ryan , Sebastian Heidenreich , Markus Bar , Gil Ariel , Avraham Be'er

Experimental studies of systems containing active proteins that undergo conformational changes driven by catalytic chemical reactions have shown that the diffusion coefficients of passive tracer particles and active molecules are larger…

Soft Condensed Matter · Physics 2017-02-27 Matthew Dennison , Raymond Kapral , Holger Stark

The identification of cellular objectives is one of the central topics in the research of microbial metabolic networks. In particular, the information about a cellular objective is needed in flux balance analysis which is a commonly used…

Molecular Networks · Quantitative Biology 2012-03-22 Tommi Aho , Juha Kesseli , Olli Yli-Harja , Stuart A. Kauffman

Understanding the system level adaptive changes taking place in an organism in response to variations in the environment is a key issue of contemporary biology. Current modeling approaches such as the constraint-based flux balance analyses…

Molecular Networks · Quantitative Biology 2007-05-23 E. Almaas , Z. N. Oltvai , A. -L. Barabasi

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

Interactions between bacteria and protozoa is an increasing area of interest, however there are a few systems that allow extensive observation of the interactions. We examined a surface system consisting of non nutrient agar with a uniform…

Quantitative Methods · Quantitative Biology 2012-10-04 George D Tsibidis , Nigel J Burroughs , William Gaze , Elizabeth M H Wellington

The prediction of battery rate performance traditionally relies on computation-intensive numerical simulations. While simplified analytical models have been developed to accelerate the calculation, they usually assume battery performance to…

Materials Science · Physics 2024-04-09 Hongxuan Wang , Fan Wang , Ming Tang

The bacterium E.Coli swims in a zig-zag manner, in a series of straight runs and tumbles occurring alternately, with the run-durations dependent on the local spatial gradient of chemo-attractants/repellants. This enables the organism to…

Cell Behavior · Quantitative Biology 2008-12-31 Melissa Reneaux , Manoj Gopalakrishnan

We present a model for a biological reactor in which bacteria tend to aggregate in flocs, as encountered in wastewater treatment plants. The influence of this flocculation on the growth dynamics of the bacteria is studied. We argue that a…

Populations and Evolution · Quantitative Biology 2007-05-23 Bart Haegeman , Claude Lobry , Jerome Harmand

Bacterial conglomerates such as biofilms and microcolonies are ubiquitous in nature and play an important role in industry and medicine. In contrast to well-mixed, diluted cultures routinely used in microbial research, bacteria in a…

Biological Physics · Physics 2017-01-13 Fred F. Farrell , Matti Gralka , Oskar Hallatschek , Bartlomiej Waclaw

Randomly moving active particles can be herded into directed motion by asymmetric geometric structures. Although such a rectification process has been extensively studied due to its fundamental, biological, and technological relevance, a…

Soft Condensed Matter · Physics 2026-03-31 Satyam Anand , Xiaolei Ma , Shuo Guo , Stefano Martiniani , Xiang Cheng