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Migrating cells exhibit various motility patterns, resulting from different migration mechanisms, cell properties, or cell-environment interactions. The complexity of cell dynamics is reflected, e.g., in the diversity of the observed forms…

Biological Physics · Physics 2023-07-07 M. Reza Shaebani , Matthieu Piel , Franziska Lautenschläger

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

In bacterial populations, cells are able to cooperate in order to yield complex collective functionalities. Interest in population-level cellular behaviour is increasing, due to both our expanding knowledge of the underlying biological…

Multiagent Systems · Computer Science 2012-11-07 Angel Goni-Moreno , Martyn Amos

In this paper, we consider the problem of learning a predictive model for population cell growth dynamics as a function of the media conditions. We first introduce a generic data-driven framework for training operator-theoretic models to…

Optimization and Control · Mathematics 2020-06-24 Shara Balakrishnan , Aqib Hasnain , Nibodh Boddupalli , Dennis M. Joshy , Robert G. Egbert , Enoch Yeung

The relationship between division of labor and individuals' spatial behavior in social insect colonies provides a useful context to study how social interactions influence the spreading of agent (which could be information or virus) across…

Populations and Evolution · Quantitative Biology 2020-03-31 Xisohui Guo , Jun Chen , Asma Azizi , Jennifer Fewell , Yun Kang

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition. How bacterial morphologies are regulated in diverse environmental conditions is a…

Cell Behavior · Quantitative Biology 2021-10-26 Diana Serbanescu , Nikola Ojkic , Shiladitya Banerjee

The ability of many living systems to actively self-propel underlies critical biomedical, environmental, and industrial processes. While such active transport is well-studied in uniform settings, environmental complexities such as geometric…

Biological Physics · Physics 2021-08-23 Alejandro Martínez-Calvo , Carolina Trenado-Yuste , Sujit S. Datta

Microbiology is the science of microbes, particularly bacteria. Many bacteria are motile: they are capable of self-propulsion. Among these, a significant class execute so-called run-and-tumble motion: they follow a fairly straight path for…

Statistical Mechanics · Physics 2012-09-06 M. E. Cates

The concentration gradient of the Bicoid morphogen, which is established during the early stages of a Drosophila melanogaster embryonic development, determines the differential spatial patterns of gene expression and subsequent cell fate…

Multiagent Systems · Computer Science 2014-12-18 Mariam Kiran , Wei Liu

In this paper we present a new analysis of energy consumption in cellular networks. We focus on the distribution of energy consumed by a base station for one isolated cell. We first define the energy consumption model in which the consumed…

Networking and Internet Architecture · Computer Science 2013-03-15 Laurent Decreusefond , Thanh-Tung Vu , Philippe Martins

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

In systems of active programmable matter, individual modules require a constant supply of energy to participate in the system's collective behavior. These systems are often powered by an external energy source accessible by at least one…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-07-21 Joshua J. Daymude , Andréa W. Richa , Jamison W. Weber

We introduce two stochastic chemostat models consisting in a coupled population-nutrient process reflecting the interaction between the nutrient and the bacterias in the chemostat with finite volume. The nutrient concentration evolves…

Probability · Mathematics 2012-06-19 Pierre Collet , Servet Martinez , Sylvie Meleard , Jaime San Martin

Cells have the ability to detect electric fields and respond to them with directed migratory movement. Investigations identified genes and proteins that play important roles in defining the migration efficiency. Nevertheless, the sensing…

Cell Behavior · Quantitative Biology 2020-10-01 Isabella Guido , Douglas Diehl , Nora Aleida Olszok , Eberhard Bodenschatz

A large number of biological systems - from bacteria to sheep - can be described as ensembles of self-propelled agents (active particles) with a complex internal dynamic that controls the agent's behavior: resting, moving slow, moving fast,…

Biological Physics · Physics 2021-09-03 L. Gómez-Nava , T. Goudon , F. Peruani

Organisms must acquire and use environmental information to guide their behaviors. However, it is unclear whether and how information quantitatively limits behavioral performance. Here, we relate information to behavioral performance in…

Biological Physics · Physics 2023-02-22 Henry H. Mattingly , Keita Kamino , Benjamin B. Machta , Thierry Emonet

One of the major characteristics of living organisms is metabolic rate, which is the amount of energy produced per unit of time. When the mass of organisms increases, the metabolic rate also increases (usually as a power function of mass),…

Other Quantitative Biology · Quantitative Biology 2024-12-02 Yuri K. Shestopaloff

This manuscript uses a statistical mechanical approach to study the effect of the adhesion, through MOCA protein, on cell locomotion. The MOCA protein regulates cell-cell adhesion, and we explore its potential role in the cell movement. We…

Cell Behavior · Quantitative Biology 2007-05-23 L. Diambra , L. C. Cintra , D. Schubert , L. da F. Costa

We study discretisation effects in cellular automata models for pedestrian dynamics by reducing the cell size. Then a particle occupies more than one cell which leads to subtle effects in the dynamics, e.g. non-local conflict situations.…

Aberrantly regulated cell motility is a hallmark of cancer cells. A hybrid agent-based model has been developed to investigate the synergistic and antagonistic cell motility-impacting effects of three microenvironment variables…

Cell Behavior · Quantitative Biology 2008-06-26 L. Leon Chen , Le Zhang , Jeongah Yoon , Thomas S. Deisboeck
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