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Here we present a new fixed parameter tractable algorithm to compute the hybridization number r of two rooted, not necessarily binary phylogenetic trees on taxon set X in time (6^r.r!).poly(n)$, where n=|X|. The novelty of this approach is…

Quantitative Methods · Quantitative Biology 2012-07-26 Teresa Piovesan , Steven Kelk

In this short note we prove that, given two (not necessarily binary) rooted phylogenetic trees T_1, T_2 on the same set of taxa X, where |X|=n, the hybridization number of T_1 and T_2 can be computed in time O^{*}(2^n) i.e. O(2^{n}…

Populations and Evolution · Quantitative Biology 2013-12-05 Leo van Iersel , Steven Kelk , Nela Lekic , Leen Stougie

Phylogenetic networks are leaf-labelled directed acyclic graphs that are used to describe non-treelike evolutionary histories and are thus a generalization of phylogenetic trees. The hybridization number of a phylogenetic network is the sum…

Data Structures and Algorithms · Computer Science 2016-06-01 Leo van Iersel , Steven Kelk , Nela Lekić , Chris Whidden , Norbert Zeh

It is a known fact that, given two rooted binary phylogenetic trees, the concept of maximum acyclic agreement forests is sufficient to compute hybridization networks with minimum hybridization number. In this work, we demonstrate by first…

Populations and Evolution · Quantitative Biology 2015-12-18 Benjamin Albrecht

It has recently been shown that the NP-hard problem of calculating the minimum number of hybridization events that is needed to explain a set of rooted binary phylogenetic trees by means of a hybridization network is fixed-parameter…

Populations and Evolution · Quantitative Biology 2012-03-20 Leo van Iersel , Simone Linz

Recently, considerable effort has been put into developing fast algorithms to reconstruct a rooted phylogenetic network that explains two rooted phylogenetic trees and has a minimum number of hybridization vertices. With the standard…

Populations and Evolution · Quantitative Biology 2011-09-16 Celine Scornavacca , Simone Linz , Benjamin Albrecht

There exist several methods dealing with the reconstruction of rooted phylogenetic networks explaining different evolutionary histories given by rooted binary phylogenetic trees. In practice, however, due to insufficient information of the…

Populations and Evolution · Quantitative Biology 2015-12-18 Benjamin Albrecht

We present efficient algorithms for computing a maximum agreement forest (MAF) of a pair of multifurcating (nonbinary) rooted trees. Our algorithms match the running times of the currently best algorithms for the binary case. The size of an…

Data Structures and Algorithms · Computer Science 2013-05-03 Chris Whidden , Robert G. Beiko , Norbert Zeh

Given a finite set $X$, a collection $\mathcal{T}$ of rooted phylogenetic trees on $X$ and an integer $k$, the Hybridization Number problem asks if there exists a phylogenetic network on $X$ that displays all trees from $\mathcal{T}$ and…

Discrete Mathematics · Computer Science 2016-03-23 Leo van Iersel , Steven Kelk , Celine Scornavacca

Given two rooted phylogenetic trees on the same set of taxa X, the Maximum Agreement Forest problem (MAF) asks to find a forest that is, in a certain sense, common to both trees and has a minimum number of components. The Maximum Acyclic…

Combinatorics · Mathematics 2012-12-27 Leo van Iersel , Steven Kelk , Nela Lekić , Leen Stougie

The Maximum Agreement Forest problem has been extensively studied in phylogenetics. Most previous work is on two binary phylogenetic trees. In this paper, we study a generalized version of the problem: the Maximum Agreement Forest problem…

Data Structures and Algorithms · Computer Science 2016-09-06 Feng Shi , Jianer Chen , Qilong Feng , Jianxin Wang

Evolutionary scenarios displaying reticulation events are often represented by rooted phylogenetic networks. Due to biological reasons, those events occur very rarely, and, thus, networks containing a minimum number of such events,…

Populations and Evolution · Quantitative Biology 2015-12-18 Benjamin Albrecht

We show that the problem of computing the hybridization number of two rooted binary phylogenetic trees on the same set of taxa X has a constant factor polynomial-time approximation if and only if the problem of computing a minimum-size…

Combinatorics · Mathematics 2011-12-23 Steven Kelk , Leo van Iersel , Nela Lekic , Simone Linz , Celine Scornavacca , Leen Stougie

Throughout the last decade, we have seen much progress towards characterising and computing the minimum hybridisation number for a set P of rooted phylogenetic trees. Roughly speaking, this minimum quantifies the number of hybridisation…

Populations and Evolution · Quantitative Biology 2021-04-13 Simone Linz , Charles Semple

The hybridization number problem requires us to embed a set of binary rooted phylogenetic trees into a binary rooted phylogenetic network such that the number of nodes with indegree two is minimized. However, from a biological point of view…

Data Structures and Algorithms · Computer Science 2016-09-05 Leo van Iersel , Steven Kelk , Georgios Stamoulis , Leen Stougie , Olivier Boes

We study the problem of finding a temporal hybridization network for a set of phylogenetic trees that minimizes the number of reticulations. First, we introduce an FPT algorithm for this problem on an arbitrary set of $m$ binary trees with…

Data Structures and Algorithms · Computer Science 2022-11-09 Sander Borst , Leo van Iersel , Mark Jones , Steven Kelk

We present new and improved fixed-parameter algorithms for computing maximum agreement forests (MAFs) of pairs of rooted binary phylogenetic trees. The size of such a forest for two trees corresponds to their subtree prune-and-regraft…

Populations and Evolution · Quantitative Biology 2015-03-19 Chris Whidden , Robert G. Beiko , Norbert Zeh

We give a 2-approximation algorithm for the Maximum Agreement Forest problem on two rooted binary trees. This NP-hard problem has been studied extensively in the past two decades, since it can be used to compute the rooted Subtree…

Data Structures and Algorithms · Computer Science 2018-11-15 Neil Olver , Frans Schalekamp , Suzanne van der Ster , Leen Stougie , Anke van Zuylen

It has remained an open question for some time whether, given a set of not necessarily binary (i.e. "nonbinary") trees T on a set of taxa X, it is possible to determine in time f(r).poly(m) whether there exists a phylogenetic network that…

Populations and Evolution · Quantitative Biology 2012-08-03 Steven Kelk , Celine Scornavacca

An evolutionary tree (phylogenetic tree) is a binary, rooted, unordered tree that models the evolutionary history of currently living species in which leaves are labeled by species. In this paper, we investigate the problem of finding the…

Populations and Evolution · Quantitative Biology 2013-04-02 Soheil Jahangiri Tazehkand , Seyed Naser Hashemi , Hadi Poormohammadi
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