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Computer simulations offer a robust toolset for exploring complex systems across various disciplines. A particularly impactful approach within this realm is Agent-Based Modeling (ABM), which harnesses the interactions of individual agents…

Artificial Intelligence · Computer Science 2023-12-19 Zengqing Wu , Run Peng , Xu Han , Shuyuan Zheng , Yixin Zhang , Chuan Xiao

When designing systems that are complex, dynamic and stochastic in nature, simulation is generally recognised as one of the best design support technologies, and a valuable aid in the strategic and tactical decision making process. A…

Neural and Evolutionary Computing · Computer Science 2013-05-30 Peer-Olaf Siebers , Uwe Aickelin

Business process simulation (BPS) is a versatile technique for estimating process performance across various scenarios. Traditionally, BPS approaches employ a control-flow-first perspective by enriching a process model with simulation…

Multiagent Systems · Computer Science 2024-08-19 Lukas Kirchdorfer , Robert Blümel , Timotheus Kampik , Han van der Aa , Heiner Stuckenschmidt

This paper deals with the cellular biological network analysis of the tumor-growth model, consisting of multiple spaces and time scales. In this paper, we present a model in graph simulation using ABM for tumor growth. In particular, we…

Multiagent Systems · Computer Science 2019-09-05 Ghazal Tashakor , Remo Suppi

There are numerous scenarios in which populations of cells migrate in crowded environments. Typical examples include wound healing, cancer growth and embryo development. In these crowded environments cells are able to interact with each…

Cell Behavior · Quantitative Biology 2019-07-03 Christian A. Yates , George Chappelle

Modeling and simulation (M&S) has revolutionized the way modern engineered products are designed, tested and evaluated. Yet modeling and simulation is much less frequently applied in the study of natural biological and active matter…

Subcellular Processes · Quantitative Biology 2021-05-07 Endre T. Somogyi , Jeffery Coulter , Fanbo Sun , Herbert M. Sauro , James A. Glazier

The topic of risk prevention and emergency response has become a key social and political concern. One approach to address this challenge is to develop Decision Support Systems (DSS) that can help emergency planners and responders to detect…

Artificial Intelligence · Computer Science 2009-04-21 Fahem Kebair , Frederic Serin

The execution and runtime performance of model-based analysis tools for realistic large-scale ABMs (Agent-Based Models) can be excessively long. This due to the computational demand exponentially proportional to the model size (e.g.…

Computation and Language · Computer Science 2024-03-08 Atiyah Elsheikh

The human brain is one of the most complex living structures in the known Universe. It consists of billions of neurons and synapses. Due to its intrinsic complexity, it can be a formidable task to accurately depict brain's structure and…

Multiagent Systems · Computer Science 2017-12-04 Ayesha Muqaddas , Muaz A. Niazi

Skin contraction is an important biophysical process that takes place during and after the recovery of deep tissue injury. This process is mainly caused by fibroblasts (skin cells) and myofibroblasts (differentiated fibroblasts) that exert…

Numerical Analysis · Mathematics 2021-05-20 Q. Peng , F. J. Vermolen

Running agent-based models (ABMs) is a burdensome computational task, specially so when considering the flexibility ABMs intrinsically provide. This paper uses a bundle of model configuration parameters along with obtained results from a…

Multiagent Systems · Computer Science 2020-01-14 Bernardo Alves Furtado

Parameter calibration is a major challenge in agent-based modelling and simulation (ABMS). As the complexity of agent-based models (ABMs) increase, the number of parameters required to be calibrated grows. This leads to the ABMS equivalent…

Machine Learning · Computer Science 2020-08-28 Rylan Perumal , Terence L van Zyl

Multi-agent simulations enables the modeling and analyses of the dynamic behaviors and interactions of autonomous entities evolving in complex environments. Agent-based models (ABM) are widely used to study emergent phenomena arising from…

Machine Learning · Computer Science 2025-05-20 Paul Saves , Nicolas Verstaevel , Benoît Gaudou

Agent-based models (ABM) are gaining traction as one of the most powerful modelling tools within the social sciences. They are particularly suited to simulating complex systems. Despite many methodological advances within ABM, one of the…

Multiagent Systems · Computer Science 2020-03-27 Le-Minh Kieu , Nicolas Malleson , Alison Heppenstall

Agent-based models (ABMs) simulate complex systems by capturing the bottom-up interactions of individual agents comprising the system. Many complex systems of interest, such as epidemics or financial markets, involve thousands or even…

This is the first part of the comprehensive review, focusing on the historical development of Agent-Based Modeling (ABM) and its classic cases. It begins by discussing the development history and design principles of Agent-Based Modeling…

Multiagent Systems · Computer Science 2025-10-22 Xiao Xue , Deyu Zhou , Ming Zhang , Fei-Yue Wang

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

Agent-based modelling and simulation offers a new and exciting way of understanding the world of work. In this paper we describe the development of an agent-based simulation model, designed to help to understand the relationship between…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Peer-Olaf Siebers , Uwe Aickelin , Helen Celia , Christopher Clegg

Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-cancer immune responses, has garnered significant attention in recent years. In our previous work arXiv:2305.12386, we developed a stochastic…

Populations and Evolution · Quantitative Biology 2026-04-23 David Morselli , Marcello E. Delitala , Adrianne L. Jenner , Federico Frascoli

Agent-based modeling and simulation has evolved as a powerful tool for modeling complex systems, offering insights into emergent behaviors and interactions among diverse agents. Integrating large language models into agent-based modeling…

Artificial Intelligence · Computer Science 2023-12-20 Chen Gao , Xiaochong Lan , Nian Li , Yuan Yuan , Jingtao Ding , Zhilun Zhou , Fengli Xu , Yong Li