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Critical infrastructures face demanding challenges due to natural and human-generated threats, such as pandemics, workforce shortages or cyber-attacks, which might severely compromise service quality. To improve system resilience,…

Multiagent Systems · Computer Science 2025-02-11 David Carramiñana , Ana M. Bernardos , Juan A. Besada , José R. Casar

Agent-based models provide a flexible framework that is frequently used for modelling many biological systems, including cell migration, molecular dynamics, ecology, and epidemiology. Analysis of the model dynamics can be challenging due to…

Dynamical Systems · Mathematics 2021-04-28 John T. Nardini , Ruth E. Baker , Matthew J. Simpson , Kevin B. Flores

Simulation-based optimization using agent-based models is typically carried out under the assumption that the gradient describing the sensitivity of the simulation output to the input cannot be evaluated directly. To still apply…

Machine Learning · Computer Science 2021-03-24 Philipp Andelfinger

Computational models are invaluable in capturing the complexities of real-world biological processes. Yet, the selection of appropriate algorithms for inference tasks, especially when dealing with real-world observational data, remains a…

Applications · Statistics 2024-10-01 Xiaoyu Wang , Ryan P. Kelly , Adrianne L. Jenner , David J. Warne , Christopher Drovandi

Autonomous Driving Systems (ADSs) are revolutionizing transportation by reducing human intervention, improving operational efficiency, and enhancing safety. Large Language Models (LLMs) have been integrated into ADSs to support high-level…

Multiagent Systems · Computer Science 2025-10-15 Yaozu Wu , Dongyuan Li , Yankai Chen , Renhe Jiang , Henry Peng Zou , Wei-Chieh Huang , Yangning Li , Liancheng Fang , Zhen Wang , Philip S. Yu

Human cognitive responses, behavioral responses, and disease dynamics co-evolve over the course of any disease outbreak, and can result in complex feedbacks. We present a dynamic agent-based model that explicitly couples the spread of…

We present some applications of an Interacting Particle System (IPS) methodology to the field of Molecular Dynamics. This IPS method allows several simulations of a switched random process to keep closer to equilibrium at each time, thanks…

Statistical Mechanics · Physics 2009-11-11 Mathias Rousset , Gabriel Stoltz

To address the major issues associated with using Time-Use Survey (TUS) for simulating residential load curves, we present the SMACH approach, which combines qualitative and quantitative data with agent-based simulation. Our model consists…

Artificial Intelligence · Computer Science 2023-12-14 Mathieu Schumann , Quentin Reynaud , François Sempé , Julien Guibourdenche , Jean-Baptiste Ly , Nicolas Sabouret

Mathematical oncology is a rapidly evolving interdisciplinary field that uses mathematical models to enhance our understanding of cancer dynamics, including tumor growth, metastasis, and treatment response. Tumor-immune interactions play a…

Quantitative Methods · Quantitative Biology 2025-11-05 Chenghang Li , Jinzhi Lei

Multi-agent systems often operate under feedback, adaptation, and non-stationarity, yet many simulation studies retain static decision rules and fixed control parameters. This paper introduces a general adaptive multi-agent learning…

Multiagent Systems · Computer Science 2025-11-26 Roberto Garrone

We envision the Full-Body AI Agent as a comprehensive AI system designed to simulate, analyze, and optimize the dynamic processes of the human body across multiple biological levels. By integrating computational models, machine learning…

Tissues and Organs · Quantitative Biology 2025-08-28 Aoqi Wang , Jiajia Liu , Jianguo Wen , Yangyang Luo , Zhiwei Fan , Liren Yang , Xi Hu , Ruihan Luo , Yankai Yu , Sophia Li , Weiling Zhao , Xiaobo Zhou

Agent-based modeling is a powerful simulation technique to understand the collective behavior and microscopic interaction in complex financial systems. Recently, the concept for determining the key parameters of the agent-based models from…

Statistical Finance · Quantitative Finance 2017-03-21 T. T. Chen , B. Zheng , Y. Li , X. F. Jiang

We theoretically and numerically study the problem of optimal control of large-scale autonomous systems under explicitly adversarial conditions, including probabilistic destruction of agents during the simulation. Large-scale autonomous…

Optimization and Control · Mathematics 2021-08-06 Theodoros Tsatsanifos , Abram H. Clark , Claire Walton , Isaac Kaminer , Qi Gong

Compartmental models (written as $CM$) and agent-based models (written as $AM$) are dominant methods in the field of epidemic simulation. But in the literature there lacks discussion on how to build the \textbf{quantitative relationship}…

Multiagent Systems · Computer Science 2022-09-20 Boyan Xu

Agent based models (ABMs) are a useful tool for modeling spatio-temporal population dynamics, where many details can be included in the model description. Their computational cost though is very high and for stochastic ABMs a lot of…

Dynamical Systems · Mathematics 2022-05-11 Stefanie Winkelmann , Johannes Zonker , Christof Schütte , Natasa Djurdjevac Conrad

We consider the problem of efficiently simulating population protocols. In the population model, we are given a distributed system of $n$ agents modeled as identical finite-state machines. In each time step, a pair of agents is selected…

Data Structures and Algorithms · Computer Science 2020-05-08 Petra Berenbrink , David Hammer , Dominik Kaaser , Ulrich Meyer , Manuel Penschuck , Hung Tran

Disease spread in most biological populations requires the proximity of agents. In populations where the individuals have spatial mobility, the contact graph is generated by the "collision dynamics" of the agents, and thus the evolution of…

Physics and Society · Physics 2007-06-07 Z. Toroczkai , H. Guclu

In this work, we introduce MedAgentSim, an open-source simulated clinical environment with doctor, patient, and measurement agents designed to evaluate and enhance LLM performance in dynamic diagnostic settings. Unlike prior approaches, our…

Computation and Language · Computer Science 2025-10-02 Mohammad Almansoori , Komal Kumar , Hisham Cholakkal

The current work addresses a virtual environment with self-replicating agents whose decisions are based on a form of "somatic computation" (soma - body) in which basic emotional responses, taken in parallelism to actual living organisms,…

Artificial Intelligence · Computer Science 2014-01-10 Carlos Pedro Gonçalves

Many complex systems can be modeled as multiagent systems in which the constituent entities (agents) interact with each other. The global dynamics of such a system is determined by the nature of the local interactions among the agents.…

Multiagent Systems · Computer Science 2011-11-10 Reinhard Laubenbacher , Abdul S. Jarrah , Henning Mortveit , S. S. Ravi
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