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Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

It has been generally recognized that stochasticity can play an important role in the information processing accomplished by reaction networks in biological cells. Most treatments of that stochasticity employ Gaussian noise even though it…

Molecular Networks · Quantitative Biology 2015-05-30 Neda Bostani , David A. Kessler , Nadav M. Shnerb , Wouter-Jan Rappel , Herbert Levine

Animals move smoothly and reliably in unpredictable environments. Models of sensorimotor control have assumed that sensory information from the environment leads to actions, which then act back on the environment, creating a single,…

Neurons and Cognition · Quantitative Biology 2023-01-11 Jing Shuang Li , Anish A. Sarma , Terrence J. Sejnowski , John C. Doyle

Nonlinear dynamics emerge through either nonlinear interactions between the variables or through nonlinearities imposed on their linear interactions. Their interactions can be conceptualized as modulations of input-output (I/O) functions,…

Dynamical Systems · Mathematics 2021-05-27 Christoforos Papasavvas

Arterial blood pressure is a key vital sign for the health of the human body. As such, accurate and reproducible measurement techniques are necessary for successful diagnosis. Blood pressure measurement is an example of molecular…

Information Theory · Computer Science 2014-10-22 Malcolm Egan , Adam Noel , Yansha Deng , Maged Elkashlan , Trung Q. Duong

Agents acting in the natural world aim at selecting appropriate actions based on noisy and partial sensory observations. Many behaviors leading to decision mak- ing and action selection in a closed loop setting are naturally phrased within…

Machine Learning · Statistics 2014-06-30 Alex Susemihl , Ron Meir , Manfred Opper

Biological information processing as implemented by regulatory and signaling networks in living cells requires sufficient specificity of molecular interaction to distinguish signals from one another, but much of regulation and signaling…

Biomolecules · Quantitative Biology 2015-01-29 Christopher R. Myers

We describe a mechanism for biological learning and adaptation based on two simple principles: (I) Neuronal activity propagates only through the network's strongest synaptic connections (extremal dynamics), and (II) The strengths of active…

Disordered Systems and Neural Networks · Physics 2009-10-31 Per Bak , Dante R Chialvo

Translation is a key step in the synthesis of proteins. Accordingly, cells have evolved an intricate array of control mechanisms to regulate this process. By constructing a multi-component mathematical framework for translation we uncover…

Biological Physics · Physics 2019-12-04 Liang Wang , M. Carmen Romano , Fordyce A. Davidson

Controlling a dynamical system is the ability of changing its configuration arbitrarily through a suitable choice of inputs. It is a very well studied concept in control theory, with wide ranging applications in medicine, biology, social…

Systems and Control · Electrical Eng. & Systems 2020-07-23 Sergiu Ivanov , Ion Petre

We demonstrate that time-delayed feedback control can be improved by adaptively tuning the feedback gain. This adaptive controller is applied to the stabilization of an unstable fixed point and an unstable periodic orbit embedded in a…

Adaptation and Self-Organizing Systems · Physics 2016-08-10 Judith Lehnert , Philipp Hövel , Valentin Flunkert , Peter Yu. Guzenko , Alexander L. Fradkov , Eckehard Schöll

In many biological networks the responses of individual elements are ambiguous. We consider a scenario in which many sensors respond to a shared signal, each with limited information capacity, and ask that the outputs together convey as…

Biological Physics · Physics 2025-12-30 Marianne Bauer , William Bialek

Gating mechanisms have emerged as an effective strategy integrated into model designs beyond recurrent neural networks for addressing long-range dependency problems. In a broad understanding, it provides adaptive control over the…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Yifan Wang , Xu Ma , Yitian Zhang , Zhongruo Wang , Sung-Cheol Kim , Vahid Mirjalili , Vidya Renganathan , Yun Fu

A model of sensory information processing is presented. The model assumes that learning of internal (hidden) generative models, which can predict the future and evaluate the precision of that prediction, is of central importance for…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Andras Lorincz

In this paper, a diffusion-based molecular communication channel between two nano-machines is considered. The effect of the amount of memory on performance is characterized, and a simple memory-limited decoder is proposed and its…

Biological Physics · Physics 2014-05-05 Reza Mosayebi , Hamidreza Arjmandi , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

Signal transduction in biological cells is effected by signaling pathways that typically include multiple feedback loops. Here we analyze information transfer through a prototypical signaling module with biochemical feedback. The module…

Biological Physics · Physics 2015-11-06 Gerardo Aquino , Martin Zapotocky

Molecular Communications (MC) underpins signaling in biological systems, enabling information transfer through biochemical molecules. The prospect of engineering this natural communication mechanism has inspired the Internet of Bio-Nano…

Emerging Technologies · Computer Science 2023-05-12 Murat Kuscu

In this paper, a biologically-inspired adaptive intelligent secondary controller is developed for microgrids to tackle system dynamics uncertainties, faults, and/or disturbances. The developed adaptive biologically-inspired controller…

Systems and Control · Electrical Eng. & Systems 2025-10-20 Mohammad Jafari , Vahid Sarfi , Amir Ghasemkhani , Hanif Livani , Lei Yang , Hao Xu

The inheritance of characteristics induced by the environment has often been opposed to the theory of evolution by natural selection. Yet, while evolution by natural selection requires new heritable traits to be produced and transmitted, it…

Populations and Evolution · Quantitative Biology 2015-06-18 Olivier Rivoire , Stanislas Leibler

The architecture of a neural network controlling an unknown environment is presented. It is based on a randomly connected recurrent neural network from which both perception and action are simultaneously read and fed back. There are two…

Adaptation and Self-Organizing Systems · Physics 2015-01-20 Mathieu Galtier
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