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We use coarse-grained Monte Carlo simulations to study the elastic properties of charged membranes in solutions of monovalent and pentavalent counterions. The simulation results of the two cases reveal trends opposite to each other. The…

Soft Condensed Matter · Physics 2014-09-12 Yotam Y. Avital , Niels Grønbech-Jensen , Oded Farago

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady…

Soft Condensed Matter · Physics 2009-11-13 Sanoop Ramachandran , P. B. Sunil Kumar , Mohamed Laradji

Cells use homeostatic mechanisms to maintain an optimal composition of distinct types of phospholipids in cellular membranes. The hydrophilic dipolar layer at the membrane interface, composed of phospholipid headgroups, regulates the…

Soft Condensed Matter · Physics 2021-07-13 Hanne S. Antila , Anika Wurl , O. H. Samuli Ollila , Markus S. Miettinen , Tiago M. Ferreira

We study the dynamics of the solid to liquid transition for a model material made of elastic particles immersed in a viscous fluid. The interaction between particle surfaces includes their viscous lubrication, a sharp repulsion when they…

Fluid Dynamics · Physics 2015-05-14 P. Rognon , I. Einav , C. Gay

We consider how membrane fluctuations can modify the miscibility of lipid mixtures, that is to say how the phase diagram of a boundary-constrained membrane is modified when the membrane is allowed to fluctuate freely in the case of zero…

Soft Condensed Matter · Physics 2015-06-11 David S. Dean , V. Adrian Parsegian , R. Podgornik

Spatiotemporal patterns in multicellular systems are important to understanding tissue dynamics, for instance, during embryonic development and disease. Here, we use a multiphase field model to study numerically the behavior of a…

Soft Condensed Matter · Physics 2025-02-13 Michael Chiang , Austin Hopkins , Benjamin Loewe , M. Cristina Marchetti , Davide Marenduzzo

We analyze the changes in the vicinal acidity (pH) at a spherical amphiphilic membrane. The membrane is assumed to contain solvent accessible, embedded, dissociable, charge regulated moieties. Basing our approach on the linear…

Soft Condensed Matter · Physics 2023-08-16 Petch Khunpetch , Arghya Majee , Hu Ruixuan , Rudolf Podgornik

We employ the phospholipid bilayer membranes of giant unilamellar vesicles as a free-standing environment for the growth of membrane-integrated ultrathin phospholipid crystals possessing a variety of shapes with 6-fold symmetry. Crystal…

Soft Condensed Matter · Physics 2024-07-09 Hao Wan , Geunwoong Jeon , Gregory M. Grason , Maria M. Santore

Nonequilibrium molecular dynamics simulations are used to study the deformation behavior of disperse polymer melts by tracking test chains of length N = Mw, the weight average molecular weight, in melts of varying dispersity. At high strain…

Soft Condensed Matter · Physics 2025-07-29 Taofeek Tejuosho , Janani Sampath

We study experimentally a coiling instability of cylindrical multilamellar stacks of phospholipid membranes, induced by polymers with hydrophobic anchors grafted along their hydrophilic backbone. Our system is unique in that coils form in…

Soft Condensed Matter · Physics 2009-10-31 Ilan Tsafrir , Marie-Alice Guedeau-Boudeville , Daniel Kandel , Joel Stavans

Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation and vesiculation. However, it is not clear how the local surface…

Cell Behavior · Quantitative Biology 2016-04-28 Padmini Rangamani , Kranthi Kiran Mandadapu , George Oster

The intermittent transition between slow growth and rapid shrinkage in polymeric assemblies is termed dynamic instability, a feature observed in a variety of biochemically distinct assemblies including microtubules, actin and their…

Soft Condensed Matter · Physics 2015-05-28 Stefano Zapperi , L. Mahadevan

Hydrodynamic instabilities in miscible fluids are ubiquitous, from natural phenomena up to geological scales, to industrial and technological applications, where they represent the only way to control and promote mixing at low Reynolds…

Soft Condensed Matter · Physics 2017-12-21 Domenico Truzzolillo , Luca Cipelletti

Recent experiments by Kantsler et. al. (2007) have shown that the relaxational dynamics of a vesicle in external elongation flow is accompanied by the formation of wrinkles on a membrane. Motivated by these experiments we present a theory…

Soft Condensed Matter · Physics 2013-05-29 K. S. Turitsyn , S. S. Vergeles

We formulate a theory of electrostatic interactions in lipid bilayer membranes where both monolayer leaflets contain dissociable moieties that are subject to charge regulation. We specifically investigate the coupling between membrane…

Soft Condensed Matter · Physics 2022-04-01 Petch Khunpetch , Arghya Majee , Rudolf Podgornik

We develop a self-consistent free-energy framework in which membrane shape and osmotic pressure are determined simultaneously in a finite reservoir by minimizing bending elasticity and solute entropy. Solute conservation makes osmotic…

A theory of a lateral stress relaxation in a fluid bilayer membrane under a step-like pressure pulse is proposed. It is shown theoretically that transfer of lipid molecules into a strained region may lead to a substantial decrease of the…

Soft Condensed Matter · Physics 2007-05-23 S. I. Mukhin , S. V. Baoukina

The dynamics of flexible polymer molecules are often assumed to be governed by hydrodynamics of the solvent. However there is considerable evidence that internal dissipation of a polymer contributes as well. Here we investigate the dynamics…

Soft Condensed Matter · Physics 2013-05-29 J. M. Deutsch

We study avenues to shape multistability and shape-morphing in flexible crystalline membranes of cylindrical topology, enabled by glide mobility of dislocations. Using computational modeling, we obtain states of mechanical equilibrium…

Soft Condensed Matter · Physics 2022-03-23 Andrei Zakharov , Daniel A. Beller

Many lipid membrane-mediated transport processes--such as mechanically-gated channel activation and solute transport--involve structural and dynamical features on membrane thickness length scales. Most existing membrane models, however,…

Soft Condensed Matter · Physics 2025-08-29 Zachary G. Lipel , Yannick A. D. Omar , Dimitrios Fraggedakis