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This study examines the stability of a flexible material interface between two fluids of the same viscosity in interaction with a free surface. When the layers are motionless, we provide evidence for the onset of a novel instability by…

Fluid Dynamics · Physics 2024-11-05 Joris Labarbe

The detachment dynamics of a fluid membrane with an isotropic spontaneous curvature from a flat substrate are studied by using meshless membrane simulations. The membrane is detached from an open edge leading to vesicle formation. With…

Soft Condensed Matter · Physics 2019-11-11 Hiroshi Noguchi

In this study, we examine the impact of imidazolium based ILs on the viscoelasticity, dynamics, and phase behavior of two model membrane systems, (i) lipid monolayers and (ii) unilamellar vesicles composed of dipalmitoylphosphatidylcholine…

Soft Condensed Matter · Physics 2025-05-05 V. K. Sharma , J. Gupta , H. Srinivasan , P. Hitaishi , S. K. Ghosh , S. Mitra

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan

We study the shape dynamics of a two-component fluid membrane, using a dynamical triangulation monte carlo simulation and a Langevin description. Phase separation induces morphology changes depending on the lateral mobility of the lipids.…

Soft Condensed Matter · Physics 2009-10-30 P. B. Sunil Kumar , Madan Rao

Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…

Biological Physics · Physics 2024-05-27 Naoki Takeishi , Masaya Santo , Naoto Yokoyama , Shigeo Wada

Biological membranes constantly change their shape in response to external stimuli, and understanding the remodeling and stability of vesicles in heterogeneous environments is therefore of fundamental importance for a range of cellular…

Soft Condensed Matter · Physics 2022-12-20 Håkan Wennerström , Emma Sparr , Joakim Stenhammar

In hydrodynamic descriptions of lipid bilayers, the membrane is often approximated as being impermeable to the surrounding, solute-containing fluid. However, biological and in vitro lipid membranes are influenced by their permeability and…

Soft Condensed Matter · Physics 2026-02-24 Amaresh Sahu

Using a microfluidic trap, we study the behavior of individual phospholipid vesicles in contact with fatty acids. We show that spontaneous fatty acids insertion inside the bilayer is controlled by the vesicle size, osmotic pressure…

Subcellular Processes · Quantitative Biology 2016-12-14 Julien Dervaux , Vincent Noireaux , Albert Libchaber

We theoretically investigate the relaxation dynamics of a nearly-flat binary lipid bilayer membrane by taking into account the membrane tension, hydrodynamics of the surrounding fluid, inter-monolayer friction and mutual diffusion in each…

Soft Condensed Matter · Physics 2016-05-05 Ryuichi Okamoto , Yuichi Kanemori , Shigeyuki Komura , Jean-Baptiste Fournier

Lipid membranes, fundamental to cellular function, undergo various mechanical deformations. Accurate modeling of these processes necessitates a thorough understanding of membrane elasticity. The lateral shear modulus, a critical parameter…

Soft Condensed Matter · Physics 2024-12-02 Konstantin V. Pinigin

We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation, the membrane bends at the point of…

Soft Condensed Matter · Physics 2011-08-26 Chen-Hsi Huang , Pai-Yi Hsiao , Fan-Gang Tseng , Shih-Kang Fan , Chien-Chung Fu , Rong-Long Pan

Using molecular dynamics, this study investigates the local elastic properties of transverse shear deformation of lipid membranes. The analysis demonstrates that transverse shear deformation induces anisotropy in the local stress profile of…

Soft Condensed Matter · Physics 2025-11-12 Konstantin V. Pinigin

How internal forces are transduced into motion through soft, fluid membranes remains a fundamental question in the study of active systems. To investigate this coupling, we develop a minimal system consisting of a single ferromagnetic…

Soft Condensed Matter · Physics 2025-07-11 Paula Magrinya , Arin Escobar Ortiz , Juan L. Aragones , Laura R. Arriaga

We theoretically investigate the dynamics of a floating lipid bilayer membrane coupled with a two-dimensional cytoskeleton network, taking into explicitly account the intermonolayer friction, the discrete lattice structure of the…

Soft Condensed Matter · Physics 2017-08-02 Ryuichi Okamoto , Shigeyuki Komura , Jean-Baptiste Fournier

We investigate the relaxation mechanism of a supercooled tetrahedral liquid at its limit of stability using isothermal isobaric ($NPT$) Monte Carlo (MC) simulations. In similarity with systems which are far from equilibrium but near the…

Statistical Mechanics · Physics 2017-09-06 Arvind Kumar Gautam , Nandlal Pingua , Aashish Goyal , Pankaj A. Apte

We develop a theoretical framework for understanding dynamic morphologies and stability of droplet interface bilayers (DIBs), accounting for lipid kinetics in the monolayers and bilayer, and droplet evaporation due to imbalance between…

Soft Condensed Matter · Physics 2018-06-13 Benjamin Guiselin , Jack O. Law , Buddhapriya Chakrabarti , Halim Kusumaatmaja

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

Soft Condensed Matter · Physics 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

We consider the hydrodynamics of lipid bilayers containing transmembrane proteins of arbitrary shape. This biologically-motivated problem is relevant to the cell membrane, whose fluctuating dynamics play a key role in phenomena ranging from…

Soft Condensed Matter · Physics 2016-10-10 Andrew Callan-Jones , Marc Durand , Jean-Baptiste Fournier

Understanding the mechanical instabilities of two-dimensional membranes has strong connection to the subjects of structure instabilities, morphology control and materials failures. In this work, we investigate the plastic mechanism…

Soft Condensed Matter · Physics 2024-04-30 Honghui Sun , Zhenwei Yao