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Growth-fragmentation processes model systems of cells that grow continuously over time and then fragment into smaller pieces. Typically, on average, the number of cells in the system exhibits asynchronous exponential growth and, upon…

Probability · Mathematics 2023-06-08 Emma Horton , Alexander R. Watson

An evolving yeast colony is simulated by means of a cellular automaton that takes care of many important features of the system under study. A complete survey of the properties of the colony is done and a set of scaling relations is found,…

Statistical Mechanics · Physics 2007-05-23 Lorenzo Fortunato

We investigate the dynamics of a colony of crawling, proliferating cells with a minimal, mechanical cell model. The cells consist of two disks, modelling the cell body and a pseudopod, connected by a finite extensible spring. The cells…

Cell Behavior · Quantitative Biology 2019-04-11 Simon K. Schnyder , John J. Molina , Ryoichi Yamamoto

The spreading of bacterial populations is central to processes in agriculture, the environment, and medicine. However, existing models of spreading typically focus on cells in unconfined settings--despite the fact that many bacteria inhabit…

Populations and Evolution · Quantitative Biology 2022-06-07 Daniel B. Amchin , Jenna A. Ott , Tapomoy Bhattacharjee , Sujit S. Datta

We study the collective dynamics of elongated swimmers in a very thin fluid layer by devising long, filamentous, non-tumbling bacteria. The strong confinement induces weak nematic alignment upon collision, which, for large enough density of…

Statistical Mechanics · Physics 2017-02-22 Daiki Nishiguchi , Ken H. Nagai , Hugues Chaté , Masaki Sano

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

A chemostat enables long-term, continuous, exponential-phase growth in an environment limited as prescribed by the researcher. It is thus a potent tool for laboratory evolution - selecting for strains with desired phenotypes. However,…

Populations and Evolution · Quantitative Biology 2018-06-04 Aryeh Wides , Ron Milo

In this paper, we study a well known two-step anaerobic digestion model in a configuration of two chemostats in series. This model is an eight-dimensional system of ordinary differential equations. Since the reaction system has a cascade…

Dynamical Systems · Mathematics 2024-08-12 Thamer Hmidhi , Radhouane Fekih-Salem , Jérôme Harmand

Hybrid models of chemotaxis combine agent-based models of cells with partial differential equation models of extracellular chemical signals. In this paper, travelling wave properties of hybrid models of bacterial chemotaxis are…

Biological Physics · Physics 2013-02-13 Benjamin Franz , Chuan Xue , Kevin J. Painter , Radek Erban

We introduce various models for cellulose bio-degradation by micro-organisms. Those models rely on complex chemical mechanisms, involve the structure of the cellulose chains and are allowed to depend on the phenotypical traits of the…

Dynamical Systems · Mathematics 2020-11-09 Pierre-Emmanuel Jabin , Alexey Miroshnikov , Robin Young

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

We consider a stochastic model, describing the growth of two competing infections on $\mathbb{R}^d$. The growth takes place by way of spherical outbursts in the infected region, an outburst in the type 1 (2) infected region causing all…

Probability · Mathematics 2015-09-24 Maria Deijfen , Olle Häggström

The expansion of biological species in natural environments is usually described as the combined effect of individual spatial dispersal and growth. In the case of aquatic ecosystems flow transport can also be extremely relevant as an extra,…

Biological Physics · Physics 2016-08-30 Francesca Tesser , Jos C. H. Zeegers , Herman J. H. Clercx , Luc Brunsveld , Federico Toschi

We analyze a reaction-diffusion system describing the growth of microbial species in a model of flocculation type that arises in biology. Existence of global classical positive solutions is proved under general growth assumptions, with…

Analysis of PDEs · Mathematics 2023-01-19 Jeffrey Morgan , Samia Zermani

We investigate the structure and stability of the steady states for a bacterial colony model with density-suppressed motility. We treat the growth rate of bacteria as a bifurcation parameter to explore the local and global structure of the…

Analysis of PDEs · Mathematics 2020-05-15 Manjun Ma , Peng Xia , Qifeng Zhang , Matti Vuorinen

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

Populations and Evolution · Quantitative Biology 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemotactic responses to form millimeter-sized condensates…

Biological Physics · Physics 2025-05-02 Nir Livne , Ady Vaknin , Oded Agam

Models based on surfactant driven instabilities have been employed to describe pattern formation by swarming bacteria. However, by definition, such models cannot account for the effect of bacterial sensing and decision making. Here we…

This paper studies a two microbial species model in competition for a single resource in the chemostat including general interspecific density-dependent growth rates with distinct removal rates for each species. We give the necessary and…

Dynamical Systems · Mathematics 2024-01-15 Tahani Mtar , Radhouane Fekih-Salem

We study a chemotaxis-growth system with nonlinear local and nonlocal reactions and gradient-dependent damping. Under suitable conditions on the system parameters and spatial dimension, we prove that solutions exist globally in time and…

Analysis of PDEs · Mathematics 2025-07-29 Tongxing Li , Silvia Frassu , Giuseppe Viglialoro