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We present a two-species population model in a well-mixed environment where the dynamics involves, in addition to birth and death, changes due to environmental factors and inter-species interactions. The novel dynamical components are…

Biological Physics · Physics 2020-09-17 J. J. Dong , J. D. Russo , K. Sampson

We consider the classical chemostat model with an additional compartment connected by pure diffusion, and analyze its asymptotic properties. We investigate conditions under which this spatial structure is beneficial for species survival and…

Classical Analysis and ODEs · Mathematics 2017-11-28 María Crespo , Alain Rapaport

In a chemostat, bacteria live in a growth container of constant volume in which liquid is injected continuously. Recently, Campillo and Fritsch introduced a mass-structured individual-based model to represent this dynamics and proved its…

Probability · Mathematics 2017-01-24 Bertrand Cloez , Coralie Fritsch

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

Growth in bacterial populations generally depends on the environment (availability and quality of nutrients, presence of a toxic inhibitor, product inhibition..). Here, we build a model to describe the action of a bacteriostatic antibiotic,…

Biological Physics · Physics 2025-06-25 Barnabe Ledoux , David Lacoste

We study the formation of spot patterns seen in a variety of bacterial species when the bacteria are subjected to oxidative stress due to hazardous byproducts of respiration. Our approach consists of coupling the cell density field to a…

This paper theoretically analyzes a phenomenological stochastic model for bacterial growth. This model comprises cell division and the linear growth of cells, where growth rates and cell cycles are drawn from lognormal distributions. We…

Biological Physics · Physics 2016-06-28 Ken Yamamoto , Jun-ichi Wakita

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

Continuous cultures of mammalian cells are complex systems displaying hallmark phenomena of nonlinear dynamics, such as multi-stability, hysteresis, as well as sharp transitions between different metabolic states. In this context…

Molecular Networks · Quantitative Biology 2019-03-01 Jorge Fernandez-de-Cossio-Diaz , Roberto Mulet

In nature, microorganisms must often cope with hostile environmental conditions. To do so they have developed sophisticated cooperative behavior and intricate communication capabilities, such as: direct cell-cell physical interactions via…

Condensed Matter · Physics 2007-05-23 Eshel Ben-Jacob , Inon Cohen , Ido Golding , Yonathan Kozlovsky

Most conspicuous organisms are multicellular and most multicellular organisms develop somatic cells to perform specific, non-reproductive tasks. The ubiquity of this division of labor suggests that it is highly advantageous. In this paper,…

Populations and Evolution · Quantitative Biology 2008-01-18 Martin Willensdorfer

We introduce a general theoretical framework to study the shape dynamics of actively growing and remodeling surfaces. Using this framework we develop a physical model for growing bacterial cell walls and study the interplay of cell shape…

Biological Physics · Physics 2016-04-08 Shiladitya Banerjee , Norbert F. Scherer , Aaron R. Dinner

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

Probability · Mathematics 2022-04-27 Nam H Nguyen , Marek Kimmel

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

We study the chemostat model for one species competing for one nutrient using a Lyapunov-type analysis. We design the dilution rate function so that all solutions of the chemostat converge to a prescribed periodic solution. In terms of…

Optimization and Control · Mathematics 2007-05-23 Frederic Mazenc , Michael Malisoff , Patrick De Leenheer

During batch growth on mixtures of two growth-limiting substrates, microbes consume the substrates either sequentially or simultaneously. These growth patterns are manifested in all types of bacteria and yeasts. The ubiquity of these growth…

Cell Behavior · Quantitative Biology 2008-01-09 Jason T. Noel , Atul Narang

Chlamydiae are bacteria with an interesting unusual developmental cycle. A single bacterium in its infectious form (elementary body, EB) enters the host cell, where it converts into its dividing form (reticulate body, RB), and divides by…

Populations and Evolution · Quantitative Biology 2023-06-06 Péter Kevei , Máté Szalai

Chloroplasts regulate their growth to optimize photosynthesis. Quantitative data shows that the ratio of total chloroplast area to mesophyll cell area is constant across different cells within a single species, and also across species.…

Subcellular Processes · Quantitative Biology 2015-09-03 Kelly M. Paton , Lisa Anderson , Pauline Flottat , Eric N. Cytrynbaum

Chemotactic bacteria have been observed to congregate into highly regular patterns. When the bacteria are placed in the center of a dish, a wave of bacteria can travel outward, leaving a regular pattern of spots or stripes in its wake.…

Pattern Formation and Solitons · Physics 2009-09-29 William J. Bruno