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This paper studies a chemotaxis system where cells move in response to a chemical signal within a confined habitat. The model includes external source terms that combine local and nonlocal growth with dampening effects. The main focus is on…

Analysis of PDEs · Mathematics 2025-11-11 Rafael Diaz Fuentes , Fatma Gamze Duzgun , Silvia Frassu , Giuseppe Viglialoro

In a growth-fragmentation system, cells grow in size slowly and split apart at random. Typically, the number of cells in the system grows exponentially and the distribution of the sizes of cells settles into an equilibrium 'asymptotic…

Probability · Mathematics 2025-01-22 Denis Villemonais , Alexander Watson

Confluent populations of elongated cells give rise to ordered patterns seen in nematic phase liquid crystals. We correlate cell elongation and intercellular distance with intercellular alignment using an amorphous spin glass model. We…

Biological Physics · Physics 2016-11-28 Sunil Pai , Nathan Loewke , Morgaine Green , Christine Cordeiro , Elise Cabral , Bertha Chen , Thomas Baer

The tolerance of bacterial populations to biocidal or antibiotic treatment has been well documented in both biofilm and planktonic settings. However, there is still very little known about the mechanisms that produce this tolerance.…

Populations and Evolution · Quantitative Biology 2008-07-15 Patrick De Leenheer , Nick Cogan

We use extreme value statistics to study the dynamics of coarsening in aggregation-fragmentation models which form condensates in the steady state. The dynamics is dominated by the formation of local condensates on a coarsening length scale…

Statistical Mechanics · Physics 2023-03-27 Chandrashekar Iyer , Arghya Das , Mustansir Barma

Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived. One of these relations implies specific inequalities…

Populations and Evolution · Quantitative Biology 2021-11-08 Reinaldo García-García , Arthur Genthon , David Lacoste

Bacteriophages spreading through populations of bacteria offer relatively simple, tuneable systems for testing mathematical models of range expansion. However, such models typically assume a static state into which to expand, which is not…

Soft Condensed Matter · Physics 2024-04-02 Rory Claydon , Samuel Gartenstein , Aidan T. Brown

The proper functioning of multicellular organisms requires the robust establishment of precise proportions between distinct cell-types. This developmental differentiation process typically involves intracellular regulatory and stochastic…

Cell Behavior · Quantitative Biology 2016-06-22 Benjamin Pfeuty , Kunihiko Kaneko

We present a theoretical study for the intermediate stages of the growth of membranes and vesicles in supersaturated solutions of amphiphilic molecules. The problem presents important differences with the growth of droplets in the classical…

Condensed Matter · Physics 2009-10-28 A. M. Somoza , U. Marini Bettolo Marconi , P. Tarazona

Coagulation-fragmentation processes describe the stochastic association and dissociation of particles in clusters. Cluster dynamics with cluster-cluster interactions for a finite number of particles has recently attracted attention…

Probability · Mathematics 2016-11-22 Nathanael Hoze , David Holcman

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

Dispersal of species to find a more favorable habitat is important in population dynamics. Dispersal rates evolve in response to the relative success of different dispersal strategies. In a simplified deterministic treatment (J. Dockery, V.…

Populations and Evolution · Quantitative Biology 2009-07-28 David A. Kessler , Leonard M. Sander

We consider a generational and continuous-time two-phase model of the cell cycle. The first model is given by a stochastic operator, and the second by a piecewise deterministic Markov process. In the second case we also introduce a…

Probability · Mathematics 2018-07-30 Katarzyna Pichór , Ryszard Rudnicki

In the development of multiscale biological models it is crucial to establish a connection between discrete microscopic or mesoscopic stochastic models and macroscopic continuous descriptions based on cellular density. In this paper a…

Biological Physics · Physics 2009-11-13 Mark Alber , Nan Chen , Pavel M. Lushnikov , Stuart A. Newman

We study the clustering of a model cyanobacterium \textit{Synechocystis} into microcolonies. The bacteria are allowed to diffuse onto surfaces of different hardness, and interact with the others by aggregation and detachment. We find that…

Biological Physics · Physics 2020-03-04 Thomas Vourc'h , Julien Léopoldès , Hassan Peerhossaini

For over two decades, Flux Balance Analysis (FBA) has been successfully used for predicting growth rates and intracellular reaction rates in microbiological metabolism. An aspect that is often omitted from this analysis, is segregation or…

Systems and Control · Electrical Eng. & Systems 2023-06-02 Michiel Busschaert , Florence H. Vermeire , Steffen Waldherr

{\it E. coli} bacteria swim in straight runs interrupted by sudden reorientation events called tumbles. The resulting random walks give rise to density fluctuations that can be derived analytically in the limit of non interacting particles…

Statistical Mechanics · Physics 2013-09-05 M. Paoluzzi , R. Di Leonardo , L. Angelani

Bacterial growth and division generally occur by the process known as binary fission, in which the cells grow polarly until they divide into two daughter cells. Although this process is affected by factors that introduce stochastic…

Soft Condensed Matter · Physics 2022-10-05 Andrés Delgado-Campos , Alejandro Cuetos

The condensational growth of spherical water microdroplets is studied in a laboratory setup and with a mathematical model. In the experiment, droplet clusters are kept in a freely levitated state within an upward-oriented flow of water…

Soft Condensed Matter · Physics 2019-06-25 Dmitrii N. Gabyshev , Alexander A. Fedorets , Nurken E. Aktaev , Otto Klemm , Stepan N. Andreev

As cells grow and divide under a given environment, they become crowded and resources are limited, as seen in bacterial biofilms and multicellular aggregates. These cells often show strong interactions through exchanging chemicals, as in…

Cell Behavior · Quantitative Biology 2017-02-08 Jumpei F Yamagishi , Nen Saito , Kunihiko Kaneko
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