Related papers: Investigation of bone resorption within a cortical…
Inspired by the synchronized beating of cilia, we show that the collective dynamics of hair-like fibers in a meniscus during fast drainage enables their self-organization into multiple topologies including complex shape inversions. By…
Ductile fracture of metallic materials typically involves the elastoplastic deformation and associated damaging process. The nonlocal lattice particle method (LPM) can be extended to model this complex behavior. Recently, a distortional…
Fibrous dysplasia (FD) is a mosaic non-inheritable genetic disorder of the skeleton in which normal bone is replaced by structurally unsound fibro-osseous tissue. There is no curative treatment for FD, partly because its pathophysiology is…
In this paper, a new progressive mesh algorithm is introduced in order to perform fast physical simulations by the use of a lattice Boltzmann method (LBM) on a single-node multi-GPU architecture. This algorithm is able to mesh automatically…
Many events in the vertebrate immune system are influenced by some element of chance. The objective of the present work is to describe affinity maturation of B lymphocytes (in which random events are perhaps the most characteristic), and to…
Randomized controlled trials estimate average treatment effects, but treatment response heterogeneity motivates personalized approaches. A critical question is whether statistically detectable heterogeneity translates into improved…
Purpose: The purpose is to design a novelty automatic diagnostic method for osteoporosis screening by using the potential capability of convolutional neural network (CNN) in feature representation and extraction, which can be incorporated…
The red blood cell (RBC) membrane is composed of a lipid bilayer and a cytoskeleton interconnected by protein junction complexes, allowing for potential sliding between the lipid bilayer and the cytoskeleton. Despite this biological…
Inspired by experimental evidence collected when processing thin films from ternary solutions made of two solutes, typically polymers, and one solvent, we computationally study the morphology formation of domains obtained in three-state…
We propose a method to determine the CKM matrix element $|V_{ub}|$ using the global $q^2$ dependence of the dispersive bound on the form factors for $B\to \pi l\nu$ decay. Since the lattice calculation of the $B\to \pi l\nu$ form factor is…
Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…
We develop a numerical methodology for the calculation of mode-I R-curves of brittle and elastoplastic lattice materials, and unveil the impact of lattice topology, relative density and constituent material behavior on the toughening…
A stochastic model is used to assess the effect of external parameters on the development of submerged biofilms on smooth and rough surfaces. The model includes basic cellular mechanisms, such as division and spreading, together with an…
Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…
We consider an immersed elastic body that is actively driven through a structured fluid by a motor or an external force. The behavior of such a system generally cannot be solved analytically, necessitating the use of numerical methods.…
Lattice Boltzmann Method (LBM) is used to simulate and analyze the sedimentation of small ($15-80 \,\mu m$) columnar ice particles in the atmosphere. We are specially interested in evaluating the terminal falling velocity of columnar ice…
The skeleton is an essential shape characteristic providing a compact representation of the studied shape. Its computation on the image grid raises many issues. Due to the effects of discretization, the required properties of the skeleton -…
Vertebroplasty is a minimally invasive surgical procedure used to treat vertebral fractures, which conventionally involves injecting polymethylmethacrylate (PMMA) bone cement into the fractured vertebra. A common risk associated with…
Pattern formation in reaction-diffusion systems is of great importance in surface micro-patterning [Grzybowski et al. Soft Matter. 1, 114 (2005)], self-organization of cellular micro-organisms [Schulz et al. Annu. Rev. Microbiol. 55, 105…
Equilibrium aspects of molecular recognition of rigid biomolecules are investigated using coarse-grained lattice models. The analysis is carried out in two stages. First an ensemble of probe molecules is designed with respect to the target…