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The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…

The surface morphology of the developing mammalian brain is crucial for understanding brain function and dysfunction. Computational modeling offers valuable insights into the underlying mechanisms for early brain folding. Recent findings…

Neurons and Cognition · Quantitative Biology 2024-09-06 Jixin Hou , Zhengwang Wu , Xianyan Chen , Li Wang , Dajiang Zhu , Tianming Liu , Gang Li , Xianqiao Wang

This study presents a computational optimisation framework of a hip implant through the development of a functionally graded biomimetic lattice structure, whose design was structurally optimised to limit stress shielding. The optimisation…

Medical Physics · Physics 2026-01-27 Mahtab Vafaeefar , Conall Quinn , Kevin M. Moerman , Ted J. Vaughan

We develop a mesoscopic lattice model to study the morphology formation in interacting ternary mixtures with evaporation of one component. As concrete application of our model, we wish to capture morphologies as they are typically arising…

Quantitative computed tomography (QCT) is a widely used tool for osteoporosis diagnosis and monitoring. The assessment of cortical markers like cortical bone mineral density (BMD) and thickness is a demanding task, mainly because of the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-18 Stefan Reinhold. Timo Damm , Lukas Huber , Reimer Andresen , Reinhard Barkmann , Claus-C. Glüer , Reinhard Koch

Oscillations of free intracellular calcium concentration are thought to be important in the control of a wide variety of physiological phenomena, and there is long-standing interest in understanding these oscillations via the investigation…

Dynamical Systems · Mathematics 2024-01-31 Behnaz Rahmani , Samuel Jelbart , Vivien Kirk , James Sneyd

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

Mollusk shells are an ideal model system for understanding the morpho-elastic basis of morphological evolution of invertebrates' exoskeletons. During the formation of the shell, the mantle tissue secretes proteins and minerals that calcify…

Quantitative Methods · Quantitative Biology 2019-08-12 Shiva Rudraraju , Derek E. Moulton , Régis Chirat , Alain Goriely , Krishna Garikipati

Biodegradable elastic scaffolds have attracted more and more attention in the field of soft tissue repair and tissue engineering. These scaffolds made of porous bioelastomers support tissue ingrowth along with their own degradation. It is…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Dun Wang , Kaixuan Guo , Yanying Zhu , Jia Sun , Aliona Dreglea , Jiao Yu

Natural organisms utilize distributed actuation through their musculoskeletal systems to adapt their gait for traversing diverse terrains or to morph their bodies for varied tasks. A longstanding challenge in robotics is to emulate this…

During the reversible insertion of ions, lattices in intercalation materials undergo structural transformations. These lattice transformations generate misfit strains and volume changes that, in turn, contribute to the structural decay of…

Materials Science · Physics 2022-07-01 Delin Zhang , Ananya Renuka Balakrishna

Using the analytic and experimental techniques we present an exploratory study of the mass distribution features of the high coincidence of centre of mass of heterogeneous bone tissue in vivo and its centroid of geometry position. A…

Biological Physics · Physics 2009-08-18 Yifang Fan , Mushtaq Loan , Yubo Fan , Zongxiang Xu , Zhiyu Li

Growth-elasticity is a powerful model framework for understanding complex shape development in soft biological tissues. At each instant, by mapping how continuum building blocks have grown geometrically and how they respond elastically to…

Numerical Analysis · Mathematics 2024-10-23 Min Wu

We offer an alternative real-space description, based purely on activated processes, for the understanding of relaxation dynamics in hierarchical landscapes. To this end, we use the cluster model, a coarse-grained lattice model of a jammed…

Soft Condensed Matter · Physics 2024-06-27 Mahajabin Rahman , Stefan Boettcher

Objective: To analyze the frequency and co-occurrence of dermoscopic patterns in BCC lesions and their relationship with histopathologic subtypes, using statistical analysis and Information Theory tools such as entropy, conditional entropy,…

Quantitative Methods · Quantitative Biology 2025-04-08 Iván Matas , Begoña Acha , Francisca Silva-Clavería , Amalia Serrano , Tomás Toledo-Pastrana , Carmen Serrano

Multimodal human action understanding is a significant problem in computer vision, with the central challenge being the effective utilization of the complementarity among diverse modalities while maintaining model efficiency. However, most…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Hongsong Wang , Heng Fei , Bingxuan Dai , Jie Gui

We consider a simple one-dimensional time-dependent model for bone regeneration in the presence of a bio-resorbable polymer scaffold. Within the framework of the model, we optimize the effective mechanical stiffness of the polymer scaffold…

Tissues and Organs · Quantitative Biology 2018-09-24 Patrina S. P. Poh , Dvina Valainis , Kaushik Bhattacharya , Martijn van Griensven , Patrick Dondl

We introduce a model of fracture which includes the out-of-plane degrees of freedom necessary to describe buckling in a thin-sheet material. The model is a regular square lattice of elastic beams, rigidly connected at the nodes so as to…

Soft Condensed Matter · Physics 2007-05-23 Bjorn Skjetne , Torbjorn Helle , Alex Hansen

Recurrent neural networks have shown remarkable success in modeling sequences. However low resource situations still adversely affect the generalizability of these models. We introduce a new family of models, called Lattice Recurrent Units…

Machine Learning · Computer Science 2017-11-23 Chaitanya Ahuja , Louis-Philippe Morency

The mode structure of a Bose-Einstein condensate non-adiabatically loaded into a one-dimensional optical lattice is studied by analyzing the visibility of the interference pattern as well as the radial profile of the condensate after a…

Soft Condensed Matter · Physics 2009-11-07 O. Morsch , J. H. Müller , D. Ciampini , M. Cristiani , P. B. Blakie , C. J. Williams , P. S. Julienne , E. Arimondo