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Viruses present an amazing genetic variability. An ensemble of infecting viruses, also called a viral quasispecies, is a cloud of mutants centered around a specific genotype. The simplest model of evolution, whose equilibrium state is…

Populations and Evolution · Quantitative Biology 2026-01-14 Maxime Berger , Raphaël Cerf

Co-evolution of two coupled quasispecies is studied, motivated by the competition between viral evolution and adapting immune response. In this co-adaptive model, besides the classical error catastrophe for high virus mutation rates, a…

Statistical Mechanics · Physics 2009-11-07 Christel Kamp , Stefan Bornholdt

We investigate the profound relation between the equations of biological evolution and quantum mechanics by writing a biologically inspired equation for the stochastic dynamics of an ensemble of particles. Interesting behavior is observed…

Statistical Mechanics · Physics 2015-05-20 Ginestra Bianconi , Christoph Rahmede

We discuss a population of sequences subject to mutations and frequency-dependent selection, where the fitness of a sequence depends on the composition of the entire population. This type of dynamics is crucial to understand the evolution…

Disordered Systems and Neural Networks · Physics 2009-11-07 M. Laessig , L. Peliti , F. Tria

In this work we propose a physical model of organismal evolution, where phenotype, organism life expectancy, is directly related to genotype i.e. the stability of its proteins which can be determined exactly in the model. Simulating the…

Populations and Evolution · Quantitative Biology 2007-05-23 Konstantin B. Zeldovich , Boris E. Shakhnovich , Eugene I. Shakhnovich

Quasispecies theory predicts that there is a critical mutation probability above which a viral population will go extinct. Above this threshold the virus loses the ability to replicate the best adapted genotype, leading to a population…

Probability · Mathematics 2011-09-26 J. Theodore Cox , Rinaldo B. Schinazi

Time evolution of number of species (genera, families, and others), population of them, and size distribution of present ones and life times are studied in terms of a new model, where population of each genetic taxon increases by a (random)…

Populations and Evolution · Quantitative Biology 2007-05-23 Caglar Tuncay

Models relating to the Species-Area curve are usually defined at the species level, and concerned only with ecological timescales. We examine an individual-based model of co-evolution on a spatial lattice based on the Tangled Nature model,…

Populations and Evolution · Quantitative Biology 2007-05-23 Daniel Lawson , Henrik Jeldtoft Jensen

There is a property called localization, which is essential for applications of quantum walks. From a mathematical point of view, the occurrence of localization is known to be equivalent to the existence of eigenvalues of the time evolution…

Mathematical Physics · Physics 2026-04-21 Chusei Kiumi

Starting from the model of continuous time random walk, we focus our interest on random walks in which the probability distributions of the waiting times and jumps have fat tails characterized by power laws with exponent between 0 and 1 for…

Probability · Mathematics 2008-01-03 Rudolf Gorenflo , Entsar A. A. Abdel-Rehim

Viral quasispecies can be regarded as a swarm of genetically related mutants or a quasispecies (QS). A common formalism to approach QS is the replicator-mutator equation (RME). However, a problem with the RME is how to quantify the…

Adaptation and Self-Organizing Systems · Physics 2010-05-13 Juan Arbiza , Santiago Mirazo , Hugo Fort

The basic mechanics of evolution have been understood since Darwin. But debate continues over whether macroevolutionary phenomena are driven primary by the fitness structure of genotype space or by ecological interaction. In this paper we…

Populations and Evolution · Quantitative Biology 2012-10-22 David V. Foster , Mary M. Rorick , Tanja Gesell , Laura Feeney , Jacob G. Foster

Highly-diverse ecosystems exhibit a broad distribution of population sizes and species turnover, where species at high and low abundances are exchanged over time. We show that these two features generically emerge in the fluctuating phase…

Populations and Evolution · Quantitative Biology 2024-01-09 Thibaut Arnoulx de Pirey , Guy Bunin

We use a large single particle tracking data set to analyze the short time and small spatial scale motion of quantum dots labeling proteins in cell membranes. Our analysis focuses on the jumps which are the changes in the position of the…

Quantitative Methods · Quantitative Biology 2015-01-08 Flor A. Espinoza , Stanly L. Steinberg

A simplified form of the time dependent evolutionary dynamics of a quasispecies model with a rugged fitness landscape is solved via a mapping onto a random flux model whose asymptotic behavior can be described in terms of a random walk. The…

Statistical Mechanics · Physics 2009-11-11 Clement Sire , Satya N. Majumdar , David S. Dean

This review is an introduction to theoretical models and mathematical calculations for biological evolution, aimed at physicists. The methods in the field are naturally very similar to those used in statistical physics, although the…

Statistical Mechanics · Physics 2015-06-24 Barbara Drossel

The distribution and heritability of many traits depends on numerous loci in the genome. In general, the astronomical number of possible genotypes makes the system with large numbers of loci difficult to describe. Multilocus evolution,…

Populations and Evolution · Quantitative Biology 2012-08-01 Richard A. Neher , Boris I. Shraiman

Several populational networks present complex topologies when implemented in evolutionary algorithms. A common feature of these topologies is the emergence of a power law. Power law behavior with different scaling factors can also be…

Computation · Statistics 2022-03-08 Francisco Leonardo Bezerra Martins , José Cláudio do Nascimento

Several pathogens use evolvability as a survival strategy against acquired immunity of the host. Despite their high variability in time, some of them exhibit quite low variability within the population at any given time, a somehow…

Populations and Evolution · Quantitative Biology 2011-08-31 Ginestra Bianconi , Davide Fichera , Silvio Franz , Luca Peliti

We study the spatio-temporal evolution of wave packets in one-dimensional quasiperiodic lattices which localize linear waves. Nonlinearity (related to two-body interactions) has destructive effect on localization, as recently observed for…

Disordered Systems and Neural Networks · Physics 2015-02-26 Marco Larcher , Tetyana V. Laptyeva , Joshua D. Bodyfelt , Franco Dalfovo , Michele Modugno , Sergej Flach