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Phenotype of biological systems needs to be robust against mutation in order to sustain themselves between generations. On the other hand, phenotype of an individual also needs to be robust against fluctuations of both internal and external…

Populations and Evolution · Quantitative Biology 2015-06-26 Kunihiko Kaneko

This paper demonstrates the use of genetic algorithms for evolving: 1) a grandmaster-level evaluation function, and 2) a search mechanism for a chess program, the parameter values of which are initialized randomly. The evaluation function…

Neural and Evolutionary Computing · Computer Science 2017-11-23 Eli David , H. Jaap van den Herik , Moshe Koppel , Nathan S. Netanyahu

A model of pattern formation in living systems is presented. The pattern is achieved by the sequential interaction of two signaling pathways. The coupling of the pattern to the (thick) epithelial sheet changes is given, when the Gauss…

Tissues and Organs · Quantitative Biology 2009-05-11 Frederick W. Cummings

The relationship between genotype and phenotype plays a crucial role in determining the function and robustness of biological systems. Here the evolution progresses through the change in genotype, whereas the selection is based on the…

Populations and Evolution · Quantitative Biology 2025-02-18 Tuan Minh Pham , Kunihiko Kaneko

How to define and use the concept of inclusive fitness is a contentious topic in evolutionary theory. Inclusive fitness can be used to calculate selection on a focal gene, but it is also applied to whole organisms. Individuals are then…

Populations and Evolution · Quantitative Biology 2019-06-11 Lutz Fromhage , Michael D Jennions

We study the performance of general dynamic matching models. This model is defined by a connected graph, where nodes represent the class of items and the edges the compatibilities between items. Items of different classes arrive one by one…

Computer Science and Game Theory · Computer Science 2020-09-22 Arnaud Cadas , Josu Doncel , Jean-Michel Fourneau , Ana Bušić

This research project investigates Lenia, an artificial life platform that simulates ecosystems of digital creatures. Lenia's ecosystem consists of simple, artificial organisms that can move, consume, grow, and reproduce. The platform is…

Neural and Evolutionary Computing · Computer Science 2023-08-11 Sanyam Jain , Aarati Shrestha , Stefano Nichele

The dynamics of adaptation is difficult to predict because it is highly stochastic even in large populations. The uncertainty emerges from number fluctuations, called genetic drift, arising in the small number of particularly fit…

Populations and Evolution · Quantitative Biology 2015-06-30 Oskar Hallatschek , Lukas Geyrhofer

It is speculated that there is a relationship between 1/f noise and computational universality in cellular automata. We use genetic algorithms to search for one-dimensional and two-state, five-neighbor cellular automata which have 1/f-type…

Cellular Automata and Lattice Gases · Physics 2013-07-19 Shigeru Ninagawa

Feature selection (FS) is assumed to improve predictive performance and identify meaningful features in high-dimensional datasets. Surprisingly, small random subsets of features (0.02-1%) match or outperform the predictive performance of…

Machine Learning · Computer Science 2025-09-22 Bhavesh Neekhra , Debayan Gupta , Partha Pratim Chakrabarti

Inspired by recent experiments on DNA replication, we apply a one-dimensional nucleation-and-growth model to DNA-replication kinetics, focusing on how to extract the time-dependent nucleation rate I(t) and growth speed v from data. We…

Soft Condensed Matter · Physics 2016-10-25 Suckjoon Jun , John Bechhoefer

The dynamics of populations is rich, taking into account that both, the individual's actions and the population's fitness are coupled. The way in which an individual chooses a strategy depends off course on the interaction with other…

Biological Physics · Physics 2007-07-20 Juan G. Diaz Ochoa

The concept of fitness is introduced, and a simple derivation of the Fundamental Theorem of Natural Selection (which states that the average fitness of a population increases if its variance is nonzero) is given. After a short discussion of…

Condensed Matter · Physics 2008-02-03 Luca Peliti

Functional connectivity varies across individuals due to genetic and environmental factors, yet classical twin models typically confound non-shared environment with measurement error and are largely limited to resting-state analyses. We…

The large number of exact fitness function evaluations makes evolutionary algorithms to have computational cost. In some real-world problems, reducing number of these evaluations is much more valuable even by increasing computational…

Neural and Evolutionary Computing · Computer Science 2014-01-24 Zahra Pourbahman , Ali Hamzeh

This paper describes a methodology for analyzing the evolutionary dynamics of genetic programming (GP) using genealogical information, diversity measures and information about the fitness variation from parent to offspring. We introduce a…

Machine Learning · Computer Science 2021-08-25 Bogdan Burlacu , Michael Affenzeller , Michael Kommenda

Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

Populations and Evolution · Quantitative Biology 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes. Predicting an…

Populations and Evolution · Quantitative Biology 2015-03-23 Benedikt Bauer , Chaitanya S. Gokhale

Biological evolution depends on the passing down to subsequent generations of genetic information encoding beneficial traits, and on the removal of unfit individuals by a selection mechanism. However, selection acts on phenotypes, and is…

Populations and Evolution · Quantitative Biology 2026-05-01 Bastien Mallein , Francesco Paparella , Emmanuel Schertzer , Zsófia Talyigás

Generative models trained on finite data face a fundamental tension: their score-matching or next-token objective converges to the empirical training distribution rather than the population distribution we seek to learn. Using rule-valid…

Machine Learning · Computer Science 2026-05-12 Binxu Wang , Emma Lucia Byrnes Finn , Bingbin Liu
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