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Traceability allows stakeholders to extract and comprehend the trace links among software artifacts introduced across the software life cycle, to provide significant support for software engineering tasks. Despite its proven benefits,…

Software Engineering · Computer Science 2024-01-18 Hui Gao , Hongyu Kuang , Wesley K. G. Assunção , Christoph Mayr-Dorn , Guoping Rong , He Zhang , Xiaoxing Ma , Alexander Egyed

The protein-protein interaction (PPI) network provides an overview of the complex biological reactions vital to an organism's metabolism and survival. Even though in the past PPI network were compared across organisms in detail, there has…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Long-Huei Chen , Mohana Prasad Sathya Moorthy , Pratyaksh Sharma

The information retrieval (IR) community has a strong tradition of making the computational artifacts and resources available for future reuse, allowing the validation of experimental results. Besides the actual test collections, the…

Information Retrieval · Computer Science 2022-07-20 Timo Breuer , Jüri Keller , Philipp Schaer

In this paper, we reproduce the experimental results presented in our previous work titled "Making Users Indistinguishable: Attribute-wise Unlearning in Recommender Systems," which was published in the proceedings of the 31st ACM…

Information Retrieval · Computer Science 2025-04-01 Yuyuan Li , Junjie Fang , Chaochao Chen , Xiaolin Zheng , Yizhao Zhang , Zhongxuan Han

Understanding how molecular alterations propagate across biological systems to drive disease remains a central challenge. Although high-throughput profiling enables comprehensive characterization of tumor states, most models neglect…

Quantitative Methods · Quantitative Biology 2026-05-11 Kyle Higgins , Guadalupe Gonzalez , Dennis Veselkov , Ivan Laponogov , Kirill Veselkov

Computational protein-protein interaction (PPI) prediction techniques can contribute greatly in reducing time, cost and false-positive interactions compared to experimental approaches. Sequence is one of the key and primary information of…

Machine Learning · Computer Science 2022-03-29 Soumyadeep Debnath , Ayatullah Faruk Mollah

Trustworthy language models should provide both correct and verifiable answers. However, citations generated directly by standalone LLMs are often unreliable. As a result, current systems insert citations by querying an external retriever…

Artificial Intelligence · Computer Science 2026-04-07 Yukun Huang , Sanxing Chen , Jian Pei , Manzil Zaheer , Bhuwan Dhingra

Dependency bloat is a persistent challenge in Python projects, which increases maintenance costs and security risks. While numerous tools exist for detecting unused dependencies in Python, removing these dependencies across the source code…

Agentic workflows, where multiple AI agents collaborate to accomplish complex tasks like reasoning or planning, play a substantial role in many cutting-edge commercial applications, and continue to fascinate researchers across fields for…

Computation and Language · Computer Science 2025-11-10 Deepak Pandita , Tharindu Cyril Weerasooriya , Ankit Parag Shah , Isabelle Diana May-Xin Ng , Christopher M. Homan , Wei Wei

Background: Biological networks have a growing importance for the interpretation of high-throughput omics data. Integrative network analysis makes use of statistical and combinatorial methods to extract smaller subnetwork modules, and…

Computational Engineering, Finance, and Science · Computer Science 2014-07-23 Kasper Dinkla , Mohammed El-Kebir , Cristina-Iulia Bucur , Marco Siderius , Martine J. Smit , Michel A. Westenberg , Gunnar W. Klau

Biomedical image segmentation is a crucial part of both scientific research and clinical care. With enough labelled data, deep learning models can be trained to accurately automate specific biomedical image segmentation tasks. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Hallee E. Wong , Marianne Rakic , John Guttag , Adrian V. Dalca

Reproducibility should be a cornerstone of science as it enables validation and reuse. In recent years, the scientific community and the general public became increasingly aware of the reproducibility crisis, i.e. the wide-spread inability…

Human-Computer Interaction · Computer Science 2020-12-07 Sebastian Stefan Feger

Interaction between proteins is a fundamental mechanism that underlies virtually all biological processes. Many important interactions are conserved across a large variety of species. The need to maintain interaction leads to a high degree…

Quantitative Methods · Quantitative Biology 2016-02-25 Christoph Feinauer , Hendrik Szurmant , Martin Weigt , Andrea Pagnani

It is necessary to gather real refactoring instances while conducting empirical studies on refactoring. However, existing refactoring detection approaches are insufficient in terms of their accuracy and coverage. Reducing the manual effort…

Software Engineering · Computer Science 2021-05-20 Ryo Kuramoto , Motoshi Saeki , Shinpei Hayashi

This work introduces a companion reproducible paper with the aim of allowing the exact replication of the methods, experiments, and results discussed in a previous work [5]. In that parent paper, we proposed many and varied techniques for…

Data Structures and Algorithms · Computer Science 2019-12-30 Antonio Fariña , Miguel A. Martínez-Prieto , Francisco Claude , Gonzalo Navarro , Juan J. Lastra-Díaz , Nicola Prezza , Diego Seco

As scientific discovery becomes increasingly data-driven, software platforms are needed to efficiently organize and disseminate data from disparate sources. This is certainly the case in the field of materials science. For example,…

Software Engineering · Computer Science 2015-11-04 Patrick Huck , Anubhav Jain , Dan Gunter , Donald Winston , Kristin Persson

Research waste in biomedical science is driven by redundant studies, incomplete reporting, and the limited scalability of traditional evidence synthesis workflows. We present an AI co-scientist for scalable and transparent knowledge…

Artificial Intelligence · Computer Science 2026-01-21 Arya Rahgozar , Pouria Mortezaagha

Often the development of novel functional peptides is not amenable to high throughput or purely computational screening methods. Peptides must be synthesized one at a time in a process that does not generate large amounts of data. One way…

Biomolecules · Quantitative Biology 2020-12-14 Rainier Barrett , Andrew D. White

Protein-protein interaction (PPI) modeling has been widely studied as a binary or multi-label classification task. While emerging multimodal large language models (LLMs) can now describe single proteins, they remain unable to generate…

Computational Engineering, Finance, and Science · Computer Science 2026-05-12 Xiao Fei , Sarah Almeida Carneiro , Yang Zhang , Lawrence P. Petalidis , Achilleas Tsortos , Costas Bouyioukos , Michalis Vazirgiannis

How do living cells achieve sufficient abundances of functional protein complexes while minimizing promiscuous non-functional interactions? Here we study this problem using a first-principle model of the cell whose phenotypic traits are…

Biomolecules · Quantitative Biology 2011-01-04 Muyoung Heo , Sergei Maslov , Eugene I. Shakhnovich