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Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

We make use of ideas from the theory of complex networks to implement a machine learning classification of human DNA methylation data, that carry signatures of cancer development. The data were obtained from patients with various kinds of…

Genomics · Quantitative Biology 2017-02-22 Alexander Karsakov , Thomas Bartlett , Iosif Meyerov , Alexey Zaikin , Mikhail Ivanchenko

Single-cell technologies have revolutionized biomedical research by enabling scalable measurement of the genome, transcriptome, and proteome of multiple systems at single-cell resolution. Now widely applied to cancer models, these assays…

Genomics · Quantitative Biology 2020-05-05 Allen W Zhang , Kieran R Campbell

Semantic concepts and relations encoded in domain-specific ontologies and other medical semantic resources play a crucial role in deciphering terms in medical queries and documents. The exploitation of these resources for tackling the…

Information Retrieval · Computer Science 2020-05-19 Mohammed Maree , Israa Noor , Khaled Rabayah , Mohammed Belkhatir , Saadat M. Alhashmi

Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan

This study explores the application potential of a deep learning model based on the CNN-LSTM framework in forecasting the sales volume of cancer drugs, with a focus on modeling complex time series data. As advancements in medical technology…

Computational Engineering, Finance, and Science · Computer Science 2025-06-30 Yinghan Li , Yilin Yao , Junghua Lin , Nanxi Wang

The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational models in precision cancer diagnostics. This paper introduces Multi-Omics Graph…

We present an applied study in cancer genomics for integrating data and inferences from laboratory experiments on cancer cell lines with observational data obtained from human breast cancer studies. The biological focus is on improving…

Applications · Statistics 2010-10-07 Daniel Merl , Julia Ling-Yu Chen , Jen-Tsan Chi , Mike West

While tumor dynamic modeling has been widely applied to support the development of oncology drugs, there remains a need to increase predictivity, enable personalized therapy, and improve decision-making. We propose the use of Tumor Dynamic…

Quantitative Methods · Quantitative Biology 2023-10-24 Mark Laurie , James Lu

Lung cancer is a condition where there is abnormal growth of malignant cells that spread in an uncontrollable fashion in the lungs. Some common treatment strategies are surgery, chemotherapy, and radiation which aren't the best options due…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Ann Rachel , Pranav M Pawar , Mithun Mukharjee , Raja M , Tojo Mathew

The World Wide Web no longer consists just of HTML pages. Our work sheds light on a number of trends on the Internet that go beyond simple Web pages. The hidden Web provides a wealth of data in semi-structured form, accessible through Web…

Artificial Intelligence · Computer Science 2011-05-11 Fabian Suchanek , Aparna Varde , Richi Nayak , Pierre Senellart

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

Machine Learning · Computer Science 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

The tumor microenvironment (TME) significantly impacts cancer prognosis due to its immune composition. While therapies for altering the immune composition, including immunotherapies, have shown exciting results for treating hematological…

Quantitative Methods · Quantitative Biology 2023-10-17 Zitong Jerry Wang , Alexander M. Xu , Aman Bhargava , Matt W. Thomson

Semantic Communication (SemCom) systems, empowered by deep learning (DL), represent a paradigm shift in data transmission. These systems prioritize the significance of content over sheer data volume. However, existing SemCom designs face…

Networking and Internet Architecture · Computer Science 2024-01-19 Abdullatif Albaseer , Mohamed Abdallah

The advent of digital pathology presents opportunities for computer vision for fast, accurate, and objective solutions for histopathological images and aid in knowledge discovery. This work uses deep learning to predict genomic biomarkers -…

Computer Vision and Pattern Recognition · Computer Science 2021-03-16 Ruchi Chauhan , PK Vinod , CV Jawahar

The Semantic Web is becoming more and more a reality, as the required technologies have reached an appropriate level of maturity. However, at this stage, it is important to provide tools facilitating the use and deployment of these…

Artificial Intelligence · Computer Science 2008-11-04 Fadi Badra , Mathieu D'Aquin , Jean Lieber , Thomas Meilender

Personalized oncology aims to tailor treatment strategies to the unique molecular and clinical profiles of individual patients, moving beyond the traditional paradigm of treating the disease not the patient. Achieving this vision requires…

Business ontology can enhance the successful development of complex enterprise system; this is being achieved through knowledge sharing and the ease of communication between every entity in the domain. Through human semantic interaction…

Computers and Society · Computer Science 2014-01-13 Adeyinka K Akanbi

Determining trust of data available in the Semantic Web is fundamental for applications and users, in particular for linked open data obtained from SPARQL endpoints. There exist several proposals in the literature to annotate SPARQL query…

Databases · Computer Science 2015-03-20 C. V. Damásio , A. Analyti , G. Antoniou

With the development of the Semantic Web technology, the use of ontologies to store and retrieve information covering several domains has increased. However, very few ontologies are able to cope with the ever-growing need of frequently…

Computation and Language · Computer Science 2020-04-24 Mohammed Maree , Mohammed Belkhatir