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The application of machine learning methods to analyze changes in gene expression patterns has recently emerged as a powerful approach in cancer research, enhancing our understanding of the molecular mechanisms underpinning cancer…

Machine Learning · Computer Science 2024-09-02 Fadi Alharbi , Aleksandar Vakanski , Murtada K. Elbashir , Mohanad Mohammed

Ontology-Mediated Query Answering (OMQA) is a well-established framework to answer queries over an RDFS or OWL Knowledge Base (KB). OMQA was originally designed for unions of conjunctive queries (UCQs), and based on certain answers. More…

Databases · Computer Science 2019-11-22 Julien Corman , Guohui Xiao

The recent success of Large Language Models (LLM) in a wide range of Natural Language Processing applications opens the path towards novel Question Answering Systems over Knowledge Graphs leveraging LLMs. However, one of the main obstacles…

Artificial Intelligence · Computer Science 2025-08-26 Julio C. Rangel , Tarcisio Mendes de Farias , Ana Claudia Sima , Norio Kobayashi

Integrating multi-omics datasets through data-driven analysis offers a comprehensive understanding of the complex biological processes underlying various diseases, particularly cancer. Graph Neural Networks (GNNs) have recently demonstrated…

Machine Learning · Computer Science 2025-08-11 Jielong Lu , Zhihao Wu , Jiajun Yu , Jiajun Bu , Haishuai Wang

A primary goal of modern cancer research is to characterize tumour growth and evolution, to improve clinical forecasting and individualized treatment. Agent-based models support this endeavour but existing models either oversimplify spatial…

Quantitative Methods · Quantitative Biology 2023-01-20 Maciej Bak , Blair Colyer , Veselin Manojlović , Robert Noble

Considering today's web scenario, there is a need of effective and meaningful search over the web which is provided by Semantic Web. Existing search engines are keyword based. They are vulnerable in answering intelligent queries from the…

Information Retrieval · Computer Science 2013-05-07 Debajyoti Mukhopadhyay , Manoj Sharma , Gajanan Joshi , Trupti Pagare , Adarsha Palwe

Due to the large volume of data and information generated by a multitude of social data sources, it is a huge challenge to manage and extract useful knowledge, especially given the different forms of data, streaming data and uncertainty and…

Databases · Computer Science 2021-05-10 Bilal Abu-Salih , Pornpit Wongthongtham , Dengya Zhu , Kit Yan Chan , Amit Rudra

We introduce an approach to semantically represent and query raster data in a Semantic Web graph. We extend the GeoSPARQL vocabulary and query language to support raster data as a new type of geospatial data. We define new filter functions…

Databases · Computer Science 2020-09-11 Timo Homburg , Steffen Staab , Daniel Janke

Relational data sources are still one of the most popular ways to store enterprise or Web data, however, the issue with relational schema is the lack of a well-defined semantic description. A common ontology provides a way to represent the…

Machine Learning · Computer Science 2018-01-31 Natalia Ruemmele , Yuriy Tyshetskiy , Alex Collins

The integration of Large Language Models (LLMs) with Knowledge Graphs (KGs) offers significant synergistic potential for knowledge-driven applications. One possible integration is the interpretation and generation of formal languages, such…

Databases · Computer Science 2025-04-07 Lars-Peter Meyer , Johannes Frey , Felix Brei , Natanael Arndt

Even though modern service-oriented and data-oriented architectures promise to deliver loosely coupled control systems, they are inherently brittle as they commonly depend on a priori agreed interfaces and data models. At the same time, the…

Instrumentation and Methods for Astrophysics · Physics 2013-10-22 Wim Pessemier , Gert Raskin , Hans Van Winckel , Geert Deconinck , Philippe Saey

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li

Engineered solutions are becoming more complex and multi-disciplinary in nature. This evolution requires new techniques to enhance design and analysis tasks that incorporate data integration and interoperability across various engineering…

Artificial Intelligence · Computer Science 2022-06-22 Daniel Dunbar , Thomas Hagedorn , Mark Blackburn , John Dzielski , Steven Hespelt , Benjamin Kruse , Dinesh Verma , Zhongyuan Yu

Personalized treatment of patients based on tissue-specific cancer subtypes has strongly increased the efficacy of the chosen therapies. Even though the amount of data measured for cancer patients has increased over the last years, most…

Machine Learning · Statistics 2017-09-18 Nora K. Speicher , Nico Pfeifer

Thinking of todays web search scenario which is mainly keyword based, leads to the need of effective and meaningful search provided by Semantic Web. Existing search engines are vulnerable to provide relevant answers to users query due to…

Information Retrieval · Computer Science 2013-11-26 Debajyoti Mukhopadhyay , Manoj Sharma , Gajanan Joshi , Trupti Pagare , Adarsha Palwe

PURPOSE: The medical literature relevant to germline genetics is growing exponentially. Clinicians need tools monitoring and prioritizing the literature to understand the clinical implications of the pathogenic genetic variants. We…

The Semantic Web effort has steadily been gaining traction in the recent years. In particular,Web search companies are recently realizing that their products need to evolve towards having richer semantic search capabilities. Description…

Artificial Intelligence · Computer Science 2012-10-19 Thomas Lukasiewicz , Maria Vanina Martinez , Giorgio Orsi , Gerardo I. Simari

Cancer exhibits diverse and complex phenotypes driven by multifaceted molecular interactions. Recent biomedical research has emphasized the comprehensive study of such diseases by integrating multi-omics datasets (genome, proteome,…

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

This paper describes the analysis of a selected testbed of Semantic Web ontologies, by a SPARQL query, which determines those ontologies that can be related to the description logic DL<ForAllPiZero>, introduced in [4] and studied in [9]. We…

Artificial Intelligence · Computer Science 2012-11-26 Antonio Pisasale , Domenico Cantone
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