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Multi-technique high resolution X-ray mapping enhanced by the recent advent of 4th generation synchrotron facilities can produce colossal datasets, challenging traditional analysis methods. Such difficulty is clearly materialized when…

Recent advances in high-throughput experimentation for combinatorial studies have accelerated the discovery and analysis of materials across a wide range of compositions and synthesis conditions. However, many of the more powerful…

Photon counting detectors (PCDs) offer promising advancements in computed tomography (CT) imaging by enabling the quantification and 3D imaging of contrast agents and tissue types through multi-energy projections. However, the accuracy of…

Medical Physics · Physics 2023-10-18 Juan C. R. Luna , Mini Das

Dark-field imaging based on grating interferometry is an emerging X-ray modality in medical imaging, which is particularly capable of providing complementary diagnostic information by visualizing the microstructural properties of lung…

Medical Physics · Physics 2026-05-29 Longchao Men , Peiyuan Guo , Jincheng Lu , Yan Xu , Hongxia Yin , Zhenchang Wang , Li Zhang , Zhentian Wang

The classical method of determining the atomic structure of complex molecules by analyzing diffraction patterns is currently undergoing drastic developments. Modern techniques for producing extremely bright and coherent X-ray lasers allow a…

Biomolecules · Quantitative Biology 2015-10-12 Tomas Ekeberg , Stefan Engblom , Jing Liu

We present proof-of-concept imaging measurements of a polycrystalline material that integrate the elements of conventional high-energy X-ray diffraction microscopy with coherent diffraction imaging techniques, and that can enable in-situ…

Resolving how defects emerge and interact within the hierarchical structure of polycrystalline materials remains a core challenge in materials science. Grain-mapping methods such as three-dimensional X-ray diffraction (3DXRD) and…

The ill-posed problem of phase retrieval in optics, using one or more intensity measurements, has a multitude of applications using electromagnetic or matter waves. Many phase retrieval algorithms are computed on pixel arrays using discrete…

Image and Video Processing · Electrical Eng. & Systems 2022-09-21 J. A. Pollock , K. S. Morgan , L. C. P. Croton , M. K. Croughan , G. Ruben , N. Yagi , H. Sekiguchi , M. J. Kitchen

X-ray speckles have been used for a wide variety of experiments, ranging from imaging (and tomography), wavefront sensing, spatial coherence measurements all the way to x-ray photon correlation spectroscopy (XPCS) and ptychography. In the…

Medical Physics · Physics 2024-04-19 Rafael Celestre , Laurene Quenot , Christopher Ninham , Emmanuel Brun , Luca Fardin

These tutorials introduce some basics of imaging with coherent X-rays, focusing on phase contrast. We consider the transport-of-intensity equation, as one particular method for X-ray phase contrast imaging among many, before passing on to…

Image and Video Processing · Electrical Eng. & Systems 2019-02-28 David M. Paganin , Daniele Pelliccia

Sub-angstrom spatial resolution of electron density coupled with sub-femtosecond temporal resolution is required to directly observe the dynamics of the electronic structure of a molecule after photoinitiation or some other ultrafast…

X-ray absorption spectroscopy and X-ray magnetic circular dichroism have long served as indispensable tools for probing the electronic and magnetic properties of transition-metal compounds with elemental selectivity. In recent years, the…

Materials Science · Physics 2026-05-11 Hiroki Wadati , Kohei Yamamoto , Kohei Yamagami

Disordered heterostructures stand as a general description for compounds that are part of homologous series such as bismuth chalcogenides. In device engineering, van der Waals epitaxy of these compounds is very promising for applications in…

Phase retrieval, the problem of recovering lost phase information from measured intensity alone, is an inverse problem that is widely faced in various imaging modalities ranging from astronomy to nanoscale imaging. The current process of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Henry Chan , Youssef S. G. Nashed , Saugat Kandel , Stephan Hruszkewycz , Subramanian Sankaranarayanan , Ross J. Harder , Mathew J. Cherukara

Convergent beam electron diffraction (CBED) performed on two-dimensional (2D) materials recently emerged as a powerful tool to study structural and stacking defects, adsorbates, atomic 3D displacements in the layers, and the interlayer…

Mesoscale and Nanoscale Physics · Physics 2022-01-25 Tatiana Latychevskaia , Sarah Haigh , Kostya Novoselov

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt

Coherent X-ray Diffraction Imaging (CXDI) technique offers unique insights into the nanoscale world, enabling the reconstruction of 3D structures with a nanoscale resolution achieved through computational phase reconstruction from measured…

Computational Physics · Physics 2024-03-26 Fangzhou Ai , Oleg Shpyrko , Vitaliy Lomakin

We demonstrate dark-field x-ray microtomography in a compact, laboratory-based system capable of resolving attenuation, phase, and anisotropic scattering signals with micrometer-scale resolution across centimetre-scale samples. The method…

Dual-energy X-ray absorptiometry (DEXA) has been widely applied to measure bone mineral density (BMD) and soft-tissue composition of human body. However, the use of DEXA is greatly limited for low-Z materials such as soft tissues due to…

Medical Physics · Physics 2016-02-18 Huajie Han , Shenghao Wang , Kun Gao , Zhili Wang , Can Zhang , Meng Yang , Kai Zhang , Peiping Zhu

Understanding non-equilibrium phenomena, such as growth, and connecting them to equilibrium phase behavior is a major challenge, in particular for complex multicomponent materials. We use X-ray reflectivity to determine the surface…

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