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We study the translocation of a flexible polymer through a pore in a membrane induced by its adsorption on \trans side of the membrane. When temperature $T$ is higher than $T_c$, the adsorption-desorption transition temperature, attractive…

Soft Condensed Matter · Physics 2009-10-31 Pyeong Jun Park , Wokyung Sung

We investigate the problem of polymer translocation through a nanopore in the absence of an external driving force. To this end, we use the two-dimensional (2D) fluctuating bond model with single-segment Monte Carlo moves. To overcome the…

Computational Physics · Physics 2012-12-06 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying

Inspired by recent experiments on chromosomal dynamics, we introduce an exactly solvable model for the interaction between a flexible polymer and a set of motor-like enzymes. The enzymes can bind and unbind to specific sites of the polymer…

Soft Condensed Matter · Physics 2019-04-03 Stefanie Put , Takahiro Sakaue , Carlo Vanderzande

Finite-size scaling arguments naturally lead us to introduce a coordinate-dependent diffusion coefficient in a Fokker-Planck description of the late stage dynamics of unbiased polymer translocation through a membrane pore. The solution for…

Statistical Mechanics · Physics 2015-06-17 Giovanni Brandani , Fulvio Baldovin , Enzo Orlandini , Attilio L. Stella

We review recent progress on the theory of dynamics of polymer translocation through a nanopore based on the iso-flux tension propagation (IFTP) theory. We investigate both pore-driven translocation of flexible and a semi-flexible polymers,…

Soft Condensed Matter · Physics 2018-10-16 Jalal Sarabadani , Tapio Ala-Nissila

Monte Carlo (MC) simulations are used to study the dynamics of polymer translocation through a nanopore in the limit where the translocation rate is sufficiently slow that the polymer maintains a state of conformational quasi-equilibrium.…

Soft Condensed Matter · Physics 2015-06-12 James M. Polson , Anthony C. M. McCaffrey

We consider the escape of a flexible, self-avoiding polymer chain out of a confined geometry. By means of simulations, we demonstrate that the translocation time can be described by a simple scaling law that exhibits a nonlinear dependence…

Soft Condensed Matter · Physics 2009-11-11 Angelo Cacciuto , Erik Luijten

Using two dimensional Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a fluidic channel with diameter $R$ through a nanopore under a driving force $F$. Due to the crowding effect induced by the…

Soft Condensed Matter · Physics 2010-08-30 Kaifu Luo , Ralf Metzler

The translocation of a macromolecule through a nanometer-sized pore is an interesting process with important applications in the development of biosensors for single--molecule analysis and in drug delivery and gene therapy. We have carried…

Statistical Mechanics · Physics 2009-09-29 Yves Lansac , Prabal K. Maiti , Matthew A. Glaser

We investigate the dynamics of polymer translocation through a nanopore using two-dimensional Langevin dynamics simulations. In the absence of external driving force, we consider a polymer which is initially placed in the middle of the pore…

Soft Condensed Matter · Physics 2007-05-23 Ilkka Huopaniemi , Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying

We study the translocation dynamics of a polymer chain threaded through a nanopore by an external force. By means of diverse methods (scaling arguments, fractional calculus and Monte Carlo simulation) we show that the relevant dynamic…

Statistical Mechanics · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

The non-equilibrium structural and dynamical properties of semiflexible polymers confined to two dimensions are investigated by molecular dynamics simulations. Three different scenarios are considered: The force-extension relation of…

Soft Condensed Matter · Physics 2013-01-08 A. Lamura , R. G. Winkler

We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory…

Soft Condensed Matter · Physics 2018-02-14 Jalal Sarabadani , Bappa Ghosh , Srabanti Chaudhury , Tapio Ala-Nissila

We consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the {\it trans} side. Using Langevin dynamics simulations we find that the rods facilitate…

Soft Condensed Matter · Physics 2022-11-15 Hamidreza Khalilian , Jalal Sarabadani , Tapio Ala-Nissila

The translocation time of a polymer chain through an interaction energy gradient nanopore was studied by Monte Carlo simulations and the Fokker-Planck equation with double-absorbing boundary conditions. Both the simulation and calculation…

Soft Condensed Matter · Physics 2017-01-04 Meng-Bo Luo , Shuang Zhang , Fan Wu , Li-Zhen Sun

We study the passage (translocation) of a self-avoiding polymer through a membrane pore in two dimensions. In particular, we numerically measure the probability distribution Q(T) of the translocation time T, and the distribution P(s,t) of…

Statistical Mechanics · Physics 2009-02-12 Clément Chatelain , Yacov Kantor , Mehran Kardar

Hydrodynamic forces may significantly affect the motion of polymers. In sheet-like cavities, such as the cell's cytoplasm and microfluidic channels, the hydrodynamic forces are long-range. It is therefore expected that that hydrodynamic…

Soft Condensed Matter · Physics 2010-08-04 Tsvi Tlusty

Using Langevin dynamics simulations in three dimensions (3D), we investigate the dynamics of polymer translocation into the regions between two parallel plane walls with separation $R$ under a driving force $F$, respectively. Compared with…

Soft Condensed Matter · Physics 2010-08-18 Kaifu Luo , Ralf Metzler

We study the localisation of lattice polymer models near a permeable interface in two dimensions. Localisation can arise due to an interaction between the polymer and the interface, and can be altered by a preference for the bulk solvent on…

Statistical Mechanics · Physics 2024-07-24 C J Bradly , N R Beaton , A L Owczarek

We have used Langevin dynamics to simulate the forced translocation of linked polymer rings through a narrow pore. For fixed size (i.e. fixed number of monomers) the translocation time depends on the link type and on whether the rings are…

Statistical Mechanics · Physics 2020-06-24 Michele Caraglio , Enzo Orlandini , Stuart G Whittington
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