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One key challenge in talent search is how to translate complex criteria of a hiring position into a search query. This typically requires deep knowledge on which skills are typically needed for the position, what are their alternatives,…

Information Retrieval · Computer Science 2016-02-29 Viet Ha-Thuc , Ye Xu , Satya Pradeep Kanduri , Xianren Wu , Vijay Dialani , Yan Yan , Abhishek Gupta , Shakti Sinha

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Omer Sabary , Antonia Wachter-Zeh , Eitan Yaakobi

Traditionally, we usually utilize the method of shotgun to cut a DNA sequence into pieces and we have to reconstruct the original DNA sequence from the pieces, those are widely used method for DNA assembly. Emerging DNA sequence…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-04-15 Yukun Zhong , ZhiWei He , XianHong Wang , XiongBin Cao

Recently, scientists from The Craig J. Venter Institute reported construction of very long DNA molecules using a variety of experimental procedures adopting a number of working hypotheses. Finding a mathematical rule for generation of such…

Other Quantitative Biology · Quantitative Biology 2010-05-05 Sk. Sarif Hassana , Pabitra Pal Choudhury , Amita Pal , R. L. Brahmachary , Arunava Goswami

The results rendered by the search engines are mostly a linear snippet list. With the prolific increase in the dynamism of web pages there is a need for enhanced result lists from search engines in order to cope-up with the expectations of…

Information Retrieval · Computer Science 2012-02-14 K. S. Kuppusamy , G. Aghila

Based on modern single molecule techniques, we devise a number of possible experimental setups to probe local properties of DNA such as the presence of DNA-knots, loops or folds, or to obtain information on the DNA-sequence. Similarly, DNA…

Soft Condensed Matter · Physics 2007-05-23 Ralf Metzler , Tobias Ambjoernsson

Sequencing by synthesis is the underlying technology for many next-generation DNA sequencing platforms. We developed a new model, the fixed flow cycle model, to derive the distributions of sequence length for a given number of flow cycles…

Genomics · Quantitative Biology 2024-05-28 Yong Kong

Evolutionary deep intelligence has recently shown great promise for producing small, powerful deep neural network models via the synthesis of increasingly efficient architectures over successive generations. Despite recent research showing…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Audrey Chung , Paul Fieguth , Alexander Wong

Introduction: Before embarking on the design of any computer system it is first necessary to assess the magnitude of the problem. In the case of a web search engine this assessment amounts to determining the current size of the web, the…

Information Retrieval · Computer Science 2013-07-05 Andrew Trotman , Jinglan Zhang

Neural Architecture Search (NAS), aiming at automatically designing neural architectures by machines, has been considered a key step toward automatic machine learning. One notable NAS branch is the weight-sharing NAS, which significantly…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Guangrun Wang , Changlin Li , Liuchun Yuan , Jiefeng Peng , Xiaoyu Xian , Xiaodan Liang , Xiaojun Chang , Liang Lin

This chapter presents a theoretical framework for evaluating next generation search engines. We focus on search engines whose results presentation is enriched with additional information and does not merely present the usual list of 10 blue…

Information Retrieval · Computer Science 2015-11-19 Dirk Lewandowski

The time and effort involved in hand-designing deep neural networks is immense. This has prompted the development of Neural Architecture Search (NAS) techniques to automate this design. However, NAS algorithms tend to be slow and expensive;…

Machine Learning · Computer Science 2021-06-14 Joseph Mellor , Jack Turner , Amos Storkey , Elliot J. Crowley

Since its emergence in the 1990s the World Wide Web (WWW) has rapidly evolved into a huge mine of global information and it is growing in size everyday. The presence of huge amount of resources on the Web thus poses a serious problem of…

Information Retrieval · Computer Science 2011-02-04 Debajyoti Mukhopadhyay , Aritra Banik , Sreemoyee Mukherjee , Jhilik Bhattacharya , Young-Chon Kim

A method for encoding information in DNA sequences is described. The method is based on the precision-resolution framework, and is aimed to work in conjunction with a recently suggested terminator-free template independent DNA synthesis…

Information Theory · Computer Science 2020-05-14 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA…

Computational Engineering, Finance, and Science · Computer Science 2019-01-09 Steven Y. Ko , Lauren Sassoubre , Jaroslaw Zola

Protein engineering seeks to identify protein sequences with optimized properties. When guided by machine learning, protein sequence generation methods can draw on prior knowledge and experimental efforts to improve this process. In this…

Quantitative Methods · Quantitative Biology 2021-05-28 Zachary Wu , Kadina E. Johnston , Frances H. Arnold , Kevin K. Yang

In past ten years, modern societies developed enormous communication and social networks. Their classification and information retrieval processing become a formidable task for the society. Due to the rapid growth of World Wide Web, social…

Physics and Society · Physics 2016-07-14 Leonardo Ermann , Klaus M. Frahm , Dima L. Shepelyansky

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

The alignment of biological sequences such as DNA, RNA, and proteins, is one of the basic tools that allow to detect evolutionary patterns, as well as functional/structural characterizations between homologous sequences in different…

Quantitative Methods · Quantitative Biology 2023-05-01 Louise Budzynski , Andrea Pagnani

Since the arrival of next-generation sequencing technologies the amount of genetic sequencing data has increased dramatically. This has has fueled an increase in human genetics research. At the same time, with the recent advent of…

Genomics · Quantitative Biology 2016-07-04 Kristiina Ausmees , Pushpam Aji John