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Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

While artificial intelligence (AI) has become widespread, many commercial AI systems are not yet accessible to individual researchers nor the general public due to the deep knowledge of the systems required to use them. We believe that AI…

Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

Hardware Architecture · Computer Science 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

DNA nanotechnology promises to provide controllable self-assembly on the nanoscale, allowing for the design of static structures, dynamic machines and computational architectures. In this article I review the state-of-the art of DNA…

Soft Condensed Matter · Physics 2015-07-13 Thomas E. Ouldridge

It is not known how a cell manages to find a specific DNA sequence sufficiently fast to repair a broken chromosome through homologous recombination. I propose that the solution is based on a parallelized search implemented by freely…

Other Quantitative Biology · Quantitative Biology 2016-08-25 Johan Elf

Healthcare data is increasing in size at an unprecedented speed with much attention on big data analysis and Artificial Intelligence application for quality assurance, clinical training, severity triaging, and decision support. Radiology is…

Information Retrieval · Computer Science 2020-07-08 Ningcheng Li , Guy Maresh , Maxwell Cretcher , Khashayar Farsad , Ramsey Al-Hakim , John Kaufman , Judy Gichoya

With the rise of social networks, information on the internet is no longer solely organized by web pages. Rather, content is generated and shared among users and organized around their social relations on social networks. This presents new…

Information Retrieval · Computer Science 2020-05-12 Yunzhong He , Wenyuan Li , Liang-Wei Chen , Gabriel Forgues , Xunlong Gui , Sui Liang , Bo Hou

Because of the data deluge in scientific publication, finding relevant information is getting harder and harder for researchers and readers. Building an enhanced scientific search engine by taking semantic relations into account poses a…

Information Retrieval · Computer Science 2017-09-29 Bastien Latard , Jonathan Weber , Germain Forestier , Michel Hassenforder

In this work we present a system based on a Deep Learning approach, by using a Convolutional Neural Network, capable of classifying protein chains of amino acids based on the protein description contained in the Protein Data Bank. Each…

Machine Learning · Computer Science 2021-11-04 Damiano Perri , Marco Simonetti , Andrea Lombardi , Noelia Faginas-Lago , Osvaldo Gervasi

Each human genome is a 3 billion base pair set of encoding instructions. Decoding the genome using deep learning fundamentally differs from most tasks, as we do not know the full structure of the data and therefore cannot design…

Machine Learning · Computer Science 2016-05-24 Laura Deming , Sasha Targ , Nate Sauder , Diogo Almeida , Chun Jimmie Ye

This paper presents our joint research efforts on big data benchmarking with several industrial partners. Considering the complexity, diversity, workload churns, and rapid evolution of big data systems, we take an incremental approach in…

Information Retrieval · Computer Science 2013-07-02 Wanling Gao , Yuqing Zhu , Zhen Jia , Chunjie Luo , Lei Wang , Zhiguo Li , Jianfeng Zhan , Yong Qi , Yongqiang He , Shiming Gong , Xiaona Li , Shujie Zhang , Bizhu Qiu

Explosive growth in the amount of genomic data is matched by increasing power of consumer-grade computers. Even applications that require powerful servers can be quickly tested on desktop or laptop machines if we can generate representative…

Genomics · Quantitative Biology 2017-11-20 Anthony J. Greenberg

To search an optimal sub-network within a general deep neural network (DNN), existing neural architecture search (NAS) methods typically rely on handcrafting a search space beforehand. Such requirements make it challenging to extend them…

Machine Learning · Computer Science 2023-10-09 Tianyi Chen , Luming Liang , Tianyu Ding , Ilya Zharkov

Familial Searching is the process of searching in a DNA database for relatives of a certain individual. It is well known that in order to evaluate the genetic evidence in favour of a certain given form of relatedness between two…

Applications · Statistics 2015-03-20 Klaas Slooten , Ronald Meester

Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation and copy number variation profiles. Thus far, one tumor has…

Molecular Networks · Quantitative Biology 2014-09-09 Edwin Wang , Jinfeng Zou , Naif Zaman , Lenore K. Beitel , Mark Trifiro , Miltiadis Paliouras

DNA computing is an unconventional approach to computing that harnesses the parallelism and information storage capabilities of DNA molecules. It has emerged as a promising field with potential applications in solving a variety of…

Emerging Technologies · Computer Science 2024-06-04 Muhammad Asad Tariq , Rafay Junaid , Muhammad Mehdy Hasnain , Danyal Farhat

Deep Neural Networks (DNNs) are intensively used to solve a wide variety of complex problems. Although powerful, such systems require manual configuration and tuning. To this end, we view DNNs as configurable systems and propose an…

Machine Learning · Computer Science 2019-04-10 Salah Ghamizi , Maxime Cordy , Mike Papadakis , Yves Le Traon

Retrieval augmented generation has emerged as an effective method to enhance large language model performance. This approach typically relies on an internal retrieval module that uses various indexing mechanisms to manage a static…

Information Retrieval · Computer Science 2024-12-31 Guangxin He , Zonghong Dai , Jiangcheng Zhu , Binqiang Zhao , Qicheng Hu , Chenyue Li , You Peng , Chen Wang , Binhang Yuan

Sequencing large number of candidate disease genes which cause diseases in order to identify the relationship between them is an expensive and time-consuming task. To handle these challenges, different computational approaches have been…

Molecular Networks · Quantitative Biology 2019-04-16 Ali Jalilvand , Behzad Akbari , Fatemeh Zare Mirakabad , Foad Ghaderi

Neuroevolution has greatly promoted Deep Neural Network (DNN) architecture design and its applications, while there is a lack of methods available across different DNN types concerning both their scale and performance. In this study, we…

Neural and Evolutionary Computing · Computer Science 2023-02-03 Zhenhao Shuai , Hongbo Liu , Zhaolin Wan , Wei-Jie Yu , Jun Zhang