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Related papers: Holographic laser Doppler ophthalmoscopy

200 papers

We report on local superficial blood flow monitoring in biological tissue from laser Doppler holographic imaging. In time averaging recording conditions, holography acts as a narrowband bandpass filter, which, combined with a frequency…

The eye offers a unique opportunity for non-invasive exploration of cardiovascular diseases. Optical angiography in the retina requires sensitive measurements, which hinders conventional full-field laser Doppler imaging schemes. To overcome…

Medical Physics · Physics 2018-09-18 L. Puyo , M. Paques , M. Fink , J. -A. Sahel , M. Atlan

We performed non-invasive video imaging of retinal blood flow in a pigmented rat by holographic interferometry of near-infrared laser light backscattered by retinal tissue, beating against an off-axis reference beam sampled at a frame rate…

Instrumentation and Detectors · Physics 2016-07-27 Mathilde Pellizzari , Manuel Simonutti , Julie Degardin , Jose-Alain Sahel , Mathias Fink , Michel Paques , Michael Atlan

We report a demonstration of laser Doppler holography at a sustained acquisition rate of 250 Hz on a 1 Megapixel complementary metal-oxide-semiconductor (CMOS) sensor array and image display at 10 Hz frame rate. The holograms are optically…

Optics · Physics 2015-06-12 Benjamin Samson , Michael Atlan

Laser Doppler holography (LDH) is an interferometric blood flow imaging technique based on full-field measurements of the Doppler spectrum. LDH has so far been demonstrated in the retina with ultrafast cameras, typically at 75 kHz. We show…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Leo Puyo , Michel Paques , Michael Atlan

We report on an experimental demonstration of surface acoustic waves monitoring on a thin metal plate with heterodyne optical holography. Narrowband imaging of local optical pathlength modulation is achieved with a frequency-tunable…

Optics · Physics 2014-03-19 Francois Bruno , Jérôme Laurent , Daniel Royer , Michael Atlan

Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here investigate separating the different contributions to the power…

Medical Physics · Physics 2021-06-02 Léo Puyo , Michel Paques , Mathias Fink , José-Alain Sahel , Michael Atlan

Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry…

Medical Physics · Physics 2021-08-10 Léo Puyo , Michel Paques , Michael Atlan

Laser Doppler holography (LDH) is a full-field blood flow imaging technique able to reveal human retinal and choroidal blood flow with high temporal resolution. We here report on using LDH in the anterior segment of the eye without making…

A comprehensive assessment of retinal health demands reliable and precise methods to measure localized blood perfusion. Despite considerable advancements in imaging techniques, such as indocyanine green and fluorescein angiography, along…

Medical Physics · Physics 2024-03-15 Michael Atlan

Laser Doppler holography (LDH) is a full-field imaging technique that was recently used in the human eye to reveal blood flow contrasts in the retinal and choroidal vasculature non-invasively, and with high temporal resolution. We here…

Medical Physics · Physics 2020-04-01 L. Puyo , M. Paques , M. Fink , J-A Sahel , M. Atlan

High-speed digital holography reveals local blood flow contrasts in the eye fundus through deterministic signal analysis, leveraging a forward scattering model of dynamically diffused light. This approach enables the estimation of absolute…

Instrumentation and Detectors · Physics 2025-05-14 Zacharie Auray , Yann Fischer , Olivier Martinache , Michael Atlan

Full-field swept-source optical coherence tomography (FF-SS-OCT) and laser Doppler holography (LDH) are two holographic imaging techniques presenting unique capabilities for ophthalmology. We report on interlaced FF-SS-OCT and LDH imaging…

Medical Physics · Physics 2022-03-01 Léo Puyo , Hendrik Spahr , Clara Pfäffle , Gereon Hüttmann , Dierck Hillmann

We report on wide-field imaging of pulsatile motion induced by blood flow using heterodyne holographic interferometry on the thumb of a healthy volunteer, in real-time. Optical Doppler images were measured with green laser light by a…

The choroid is a highly vascularized tissues supplying the retinal pigment epithelium and photoreceptors. Its implication in retinal diseases is gaining increasing interest. However, investigating the anatomy and flow of the choroid remains…

Medical Physics · Physics 2021-06-02 Léo Puyo , Michel Paques , Mathias Fink , José-Alain Sahel , Michael Atlan

Heterodyne Holography is a variant of Digital Holography, where the optical frequencies of signal and reference arms can be freely adjusted by acousto-optic modulators. Heterodyne Holography is an extremely versatile and reliable…

Optics · Physics 2012-06-08 Michel Gross , Frédéric Verpillat , Fadwa Joud , Michael Atlan

Doppler holography is an emerging retinal imaging technique that captures the dynamic behavior of blood flow with high temporal resolution, enabling quantitative assessment of retinal hemodynamics. This requires accurate segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Marius Dubosc , Yann Fischer , Zacharie Auray , Nicolas Boutry , Edwin Carlinet , Michael Atlan , Thierry Geraud

We present a versatile computational image rendering software of optically-acquired holograms. The reported software can process 4 Megapixel 8-bit raw frames from a sensor array acquired at a sustained rate of 80 Hz. Video-rate image…

Optics · Physics 2015-06-18 Antoine Dillée , Romain Cancilliere , Fernando Lopes , Michael Atlan

This study presents a novel quantitative estimation method for total retinal arterial blood flow utilizing real-time Doppler holography at an unprecedented frame rate of 33,000 frames per second. This technique, leveraging high-speed…

Image and Video Processing · Electrical Eng. & Systems 2024-09-27 Yann Fischer , Zacharie Auray , Olivier Martinache , Marius Dubosc , Noé Topéza , Chloé Magnier , Maxime Boy-Arnould , Michael Atlan

We report a demonstration video-rate heterodyne holography in off-axis configuration. Reconstruction and display of 1 Megapixel holograms is achieved at 24 frames per second, with a graphics processing unit. Our claims are validated with…

Optics · Physics 2015-05-27 Benjamin Samson , Frédéric Verpillat , Michel Gross , Michael Atlan
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