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The actin cortex is a thin layer of actin filaments and myosin motors beneath the outer membrane of animal cells. It determines the cells' mechanical properties and forms important morphological structures. Physical descriptions of the…

Biological Physics · Physics 2020-01-29 N. Levernier , K. Kruse

We construct a generic coarse-grained dynamics of a thin inflexible planar layer of polar-ordered suspension of active particles, that is frictionally coupled to an embedding isotropic passive fluid medium with a friction coefficient…

Soft Condensed Matter · Physics 2015-11-11 Niladri Sarkar , Abhik Basu

Cytoskeletal gels are engineered prototypes that mimic the contractile behavior of a cell in-vitro. They are composed of an active polymer matrix and a liquid solvent. Their contraction kinetics is governed by two dynamic phenomena:…

Soft Condensed Matter · Physics 2023-06-01 Matteo Ferraresso , Mohammad Shojaeifard , Albert Kong , Mattia Bacca

In eukaryotic cells, motor proteins (MP) bind to cytoskeletal filaments and move along them in a directed manner generating active stresses. During cell division a spindle structure of overlapping antiparallel microtubules (MT) form whose…

Biological Physics · Physics 2018-04-27 Subhadip Ghosh , V N S Pradeep , Sudipto Muhuri , Ignacio Pagonabarraga , Debasish Chaudhuri

We investigate the effect of an anisotropic substrate on the turbulent dynamics of a simulated two dimensional active nematic. This is introduced as an anisotropic friction and an effective anisotropic viscosity, with the orientation of the…

Soft Condensed Matter · Physics 2019-06-12 D. J. G. Pearce

Cortical oscillations are thought to be involved in many cognitive functions and processes. Several mechanisms have been proposed to regulate oscillations. One prominent but understudied mechanism is gap-junctional coupling. Gap junctions…

Neurons and Cognition · Quantitative Biology 2018-07-04 Guillaume Pernelle , Wilten Nicola , Claudia Clopath

Fatigue refers to the changes in material properties caused by repeatedly applied loads. It has been widely studied for, e.g., construction materials, but much less has been done on soft materials. Here, we characterize the fatigue dynamics…

Soft Condensed Matter · Physics 2016-08-30 Thomas Gibaud , Christophe Perge , Stefan B. Lindstrom , Nicolas Taberlet , Sebastien Manneville

Fluid-structure interactions between active and passive components are important for many biological systems to function. A particular example is chromatin in the cell nucleus, where ATP-powered processes drive coherent motions of the…

Soft Condensed Matter · Physics 2024-02-15 Scott Weady , David B. Stein , Alexandra Zidovska , Michael J. Shelley

Cytoskeletal gels are prototyped to reproduce the mechanical contraction of the cytoskeleton in-vitro. They are composed of a polymer network (backbone), swollen by the presence of a liquid solvent, and active molecules (molecular motors,…

Soft Condensed Matter · Physics 2026-03-27 Matteo Ferraresso , Albert Kong , Mehadi Hasan , Gwynn J. Elfring , Daniele Agostinelli , Mattia Bacca

Experiments have shown that elasticity of disordered filamentous networks with compliant crosslinks is very different from networks with rigid crosslinks. Here, we model and analyze filamentous networks as a collection of randomly oriented…

Biological Physics · Physics 2015-06-17 A. Sharma , M. Sheinman , K. M. Heidemann , F. C. MacKintosh

Shear relaxation and dynamic density fluctuations are studied within a Rouse model, generalized to include the effects of permanent random crosslinks. We derive an exact correspondence between the static shear viscosity and the resistance…

Statistical Mechanics · Physics 2009-10-31 Kurt Broderix , Henning Loewe , Peter Mueller , Annette Zippelius

The physical gelation of colloids produces elastic structures that are commonly used to stabilize complex fluids in multiple industries. However, the ability to control the level of elastic modulus of these materials is limited by the…

Soft Condensed Matter · Physics 2021-12-21 Peng-Kai Kao , Michael J. Solomon , Mahesh Ganesan

Analyzing nonlinear conformational relaxation dynamics in elastic networks corresponding to two classical motor proteins, we find that they respond by well-defined internal mechanical motions to various initial deformations and that these…

Biomolecules · Quantitative Biology 2007-06-13 Yuichi Togashi , Alexander S. Mikhailov

We study the role of active coupling on the transport properties of homogeneously charged macromolecules in an infinitely dilute solution. An enzyme becomes actively bound to a segment of the macromolecule, exerting an electrostatic force…

Soft Condensed Matter · Physics 2024-05-24 Tapas Singha , Siao-Fong Li , Murugappan Muthukumar

We show that the vibrational response of a glassy liquid at finite frequencies can be described by continuum mechanics despite the vast degeneracy of the vibrational ground state; standard continuum elasticity assumes a unique ground state.…

Disordered Systems and Neural Networks · Physics 2015-06-23 Dmytro Bevzenko , Vassiliy Lubchenko

Recent experimental results on the static or quasistatic response of granular materials have been interpreted to suggest the inapplicability of the traditional engineering approaches, which are based on elasto-plastic models (which are…

Soft Condensed Matter · Physics 2007-05-23 Chay Goldenberg , Isaac Goldhirsch

The variational static formulation contributed in [International Journal of Engineering Science 143, 73-91 (2019)] is generalized in the present paper to model axial and flexural dynamic behaviors of elastic nano-beams by nonlocal strain…

We study the spatio-temporal dynamics of a model of polar active fluid in two dimensions. The system exhibits a transition from an isotropic to a polarized state as a function of density. The uniform polarized state is, however, unstable…

Soft Condensed Matter · Physics 2011-12-08 Luca Giomi , M. Cristina Marchetti

We investigate numerically, by a hybrid lattice Boltzmann method, the morphology and the dynamics of an emulsion made of a polar active gel, contractile or extensile, and an isotropic passive fluid. We focus on the case of a highly…

Soft Condensed Matter · Physics 2019-02-28 Giuseppe Negro , Livio Nicola Carenza , Pasquale Digregorio , Giuseppe Gonnella , Antonio Lamura

We study the viscoelasticity of an active solution of polar biofilaments and motor proteins. Using a molecular model, we derive the constitutive equations for the stress tensor in the isotropic phase and in phases with liquid crystalline…

Soft Condensed Matter · Physics 2009-11-11 T. B. Liverpool , M. Cristina Marchetti
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