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We report an experimental investigation of the spontaneous motion of liquid droplets on soft gels with a crosslinking gradient. By systematically adjusting the spatial difference in crosslinking density, we observed that millimeter-sized…

Soft Condensed Matter · Physics 2025-01-29 Weiwei Zhao , Wenjie Qian , Chang Xu , Qin Xu

Motivated by the formation of ring-like filament structures in the cortex of plant and animal cells, we study the dynamics of a two-dimensional layer of cytoskeletal filaments and motor proteins near a surface by a general continuum theory.…

Subcellular Processes · Quantitative Biology 2009-11-11 Alexander Zumdieck , Marco Cosentino Lagomarsino , Catalin Tanase , Karsten Kruse , Bela Mulder , Marileen Dogterom , Frank J"ulicher

Elastic effects in a model of disordered nematic elastomers are numerically investigated in two dimensions. Networks crosslinked in the isotropic phase exhibit unusual soft mechanical response against stretching. It arises from gradual…

Soft Condensed Matter · Physics 2009-10-31 Nariya Uchida

Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various crosslinking and other associated proteins largely determine the (visco)elastic response of cells. In this letter we…

Disordered Systems and Neural Networks · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

The structure and dynamics of important biological quasi-two-dimensional systems, ranging from cytoskeletal gels to tissues, are controlled by nematic order, flow, defects and activity. Continuum hydrodynamic descriptions combined with…

Biological Physics · Physics 2024-12-03 Waleed Mirza , Alejandro Torres-Sánchez , Guillermo Vilanova , Marino Arroyo

Computer simulations can aid in understanding how collective materials properties emerge from interactions between simple constituents. Here, we introduce a coarse-grained model that enables simulation of networks of actin filaments, myosin…

Biological Physics · Physics 2018-12-07 Simon L. Freedman , Shiladitya Banerjee , Glen M. Hocky , Aaron R. Dinner

Here we numerically study a model of excitable media, namely, a network with occasionally quiet nodes and connection weights that vary with activity on a short-time scale. Even in the absence of stimuli, this exhibits unstable dynamics,…

Disordered Systems and Neural Networks · Physics 2015-05-19 S. de Franciscis , J. J. Torres , J. Marro

A nematic liquid-crystal gel is a macroscopically homogeneous elastic medium with the rotational symmetry of a nematic liquid crystal. In this paper, we develop a general approach to the study of these gels that incorporates all underlying…

Soft Condensed Matter · Physics 2009-11-07 T. C. Lubensky , Ranjan Mukhopadhyay , Leo Radzihovsky , Xiangjun Xing

We propose and analyze a mathematical model of the mechanics of gels, consisting of the laws of balance of mass and linear momentum. We consider a gel to be an immiscible and incompressible mixture of a nonlinearly elastic polymer and a…

Analysis of PDEs · Mathematics 2012-10-17 Brandon Chabaud , Maria-Carme Calderer

We develop an automated computational modeling framework for rapid gradient-based design of multistable soft mechanical structures composed of non-identical bistable unit cells with appropriate geometric parameterization. This framework…

Numerical Analysis · Mathematics 2023-09-12 Mehran Mirramezani , Deniz Oktay , Ryan P. Adams

The stability of convection rolls in a fluid heated from below is limited by secondary instabilities, including the skew-varicose and crossroll instabilities. We observe a stability boundary defined by the same instabilities in stripe…

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

We develop a model of amoeboid cell motility based on active gel theory. Modeling the motile apparatus of a eukaryotic cell as a confined layer of finite length of poroelastic active gel permeated by a solvent, we first show that, due to…

Biological Physics · Physics 2015-06-12 A. C. Callan-Jones , R. Voituriez

Active filaments, such as microtubules with attached cargo-carrying motor proteins, are important dynamic structures for fluid transport in and around living cells. The mathematical models of active filaments appearing in the literature…

Fluid Dynamics · Physics 2025-08-19 Ilteber R. Ozdemir , Bethany Clarke , Yongyun Hwang , Eric E. Keaveny

The actin cytoskeleton in living cells has many types of crosslinkers. The mechanical interplay between these different crosslinker types is an open issue in cytoskeletal mechanics. We develop a framework to study the cooperativity and…

Soft Condensed Matter · Physics 2015-05-28 Moumita Das , D. A. Quint , J. M. Schwarz

We use the entropy method to analyze the nonlinear dynamics and stability of a continuum kinetic model of an active nematic suspension. From the time evolution of the relative entropy -- an energy-like quantity in the kinetic model -- we…

Soft Condensed Matter · Physics 2024-06-05 Scott Weady

Inspired by recent experiments of cells accumulating on anisotropic substrates, we study a two-dimensional, compressible, isotropic, active fluid in the presence of anisotropic friction. We find that regions of anisotropic friction that are…

Soft Condensed Matter · Physics 2026-03-04 Cody D. Schimming , Brian A. Camley

A constitutive relation between stress and strain relative to a reference state is the basic assumption of elasticity theory. However, in living matter, force generation is governed by motor molecule activity, which does not depend on…

Soft Condensed Matter · Physics 2026-03-17 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

It is frequent for active or living entities to find themselves embedded in a surrounding medium. Resulting composite systems are usually classified as either active fluids or active solids. Yet, in reality, particularly in the biological…

Soft Condensed Matter · Physics 2025-11-07 Henning Reinken , Andreas M. Menzel

Active gels play an important role in biology and in inspiring biomimetic active materials, due to their ability to change shape, size and create their own morphology; the relevant mechanics behind these changes is driven by…

Soft Condensed Matter · Physics 2023-09-22 Anne Bernheim-Groswasser , Gefen Livne , Paola Nardinocchi , Filippo Recrosi , Luciano Teresi
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