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We investigate flow-driven amoeboid motility as exhibited by microplasmodia of Physarum polycephalum. A poroelastic two-phase model with rigid boundaries is extended to the case of free boundaries and substrate friction. The cytoskeleton is…

Soft Condensed Matter · Physics 2018-11-14 Dirk Alexander Kulawiak , Jakob Löber , Markus Bär , Harald Engel

Dynamically crosslinked semiflexible biopolymers such as the actin cytoskeleton govern the mechanical behavior of living cells. Semiflexible biopolymers nonlinearly stiffen in response to mechanical loads, whereas the crosslinker dynamics…

Soft Condensed Matter · Physics 2019-06-05 Yuval Mulla , F. C. MacKintosh , Gijsje H. Koenderink

We develop a model for gels and entangled solutions of semiflexible biopolymers such as F-actin. Such networks play a crucial structural role in the cytoskeleton of cells. We show that the rheologic properties of these networks can result…

Condensed Matter · Physics 2009-10-28 F. C. MacKintosh , J. Kas , P. A. Janmey

We develop an effective two-dimensional coarse-grained description for the coupled system of a planar fluid membrane anchored to a thin layer of polar ordered active fluid below. The macroscopic orientation of the active fluid layer is…

Soft Condensed Matter · Physics 2013-09-16 Niladri Sarkar , Abhik Basu

Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

Soft Condensed Matter · Physics 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

The patterns arising from the differential swelling of gels are investigated experimentally and theoretically as a model for the differential growth of living tissues. Two geometries are considered: a thin strip of soft gel clamped to a…

Soft Condensed Matter · Physics 2009-11-11 Thierry Mora , Arezki Boudaoud

Models of active nematics in biological systems normally require complexity arising from the hydrodynamics involved at the microscopic level as well as the viscoelastic nature of the system. Here we show that a minimal, space-independent,…

Soft Condensed Matter · Physics 2022-06-27 Emmanuel L. C. VI M. Plan , Huong Le Thi , Julia M. Yeomans , Amin Doostmohammadi

We present a unified formulation of a rotationally invariant nonlinear elasticity for a variety of spontaneously anisotropic phases, and use it to study thermal fluctuations in nematic elastomers and spontaneously anisotropic gels. We find…

Soft Condensed Matter · Physics 2009-11-07 Xiangjun Xing , Leo Radzihovsky

Activity and renewability are distinctive features of living matter, and constitute a new class of materials that we term renewable active matter. A striking example is the cell cytoskeleton, where myosin filaments bind to the actin…

Soft Condensed Matter · Physics 2025-05-27 M. Abhishek , Ankit Dhanuka , Deb Sankar Banerjee , Madan Rao

Glass formers exhibit a viscoelastic behavior: at the laboratory timescale, they behave like (glassy) solids at low temperatures, and like liquids at high temperatures. Based on this observation, elastic models relate the long time…

Chemical Physics · Physics 2017-08-01 Emmanuel Guillaud , Laurent Joly , Dominique De Ligny , Samy Merabia

The cytoskeleton -- a collection of polymeric filaments, molecular motors, and crosslinkers -- is a foundational example of active matter, and in the cell assembles into organelles that guide basic biological functions. Simulation of…

Soft Condensed Matter · Physics 2022-06-13 Wen Yan , Saad Ansari , Adam Lamson , Matthew A. Glaser , Meredith Betterton , Michael J. Shelley

The translation and shape deformations of a passive viscous Newtonian droplet immersed in an active nematic liquid crystal under circular confinement are analyzed using a linear stability analysis. We focus on the case of a sharply aligned…

Soft Condensed Matter · Physics 2025-07-29 Tanumoy Dhar , Michael J. Shelley , David Saintillan

We numerically study the multi-scale properties of a 2d active gel to address the energy transfer mechanism. We find that activity is able to excite long-ranged distortions of the nematic pattern giving rise to spontaneous laminar flows and…

Soft Condensed Matter · Physics 2021-01-13 Livio Nicola Carenza , Luca Biferale , Giuseppe Gonnella

We analyze a model of mutually-propelled filaments suspended in a two-dimensional solvent. The system undergoes a mean-field isotropic-nematic transition for large enough filament concentrations and the nematic order parameter is allowed to…

Soft Condensed Matter · Physics 2011-05-26 L. Giomi , L. Mahadevan , B. Chakraborty , M. F. Hagan

Coupled parametric oscillators were recently employed as simulators of artificial Ising networks, with the potential to solve computationally hard minimization problems. We demonstrate a new dynamical regime within the simplest network -…

There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. However, how such features that intrinsically rely on particle…

Soft Condensed Matter · Physics 2019-02-06 Romain Mueller , Julia Yeomans , Amin Doostmohammadi

Molecular dynamics simulations have been employed to study the formation of a physical (thermoreversible) gel by amphiphilic A-B-A triblock copolymers in aqueous solution. In order to mimic the structure of hydrogel-forming polypeptides…

Soft Condensed Matter · Physics 2007-05-23 Lei Guo , Erik Luijten

Collagen is the most abundant extracellular-network-forming protein in animal biology and is important in both natural and artificial tissues, where it serves as a material of great mechanical versatility. This versatility arises from its…

Soft Condensed Matter · Physics 2009-07-13 D. Vader , A. Kabla , D. Weitz , L. Mahadevan

We study the linear stability of an isotropic active fluid in three different geometries: a film of active fluid on a rigid substrate, a cylindrical thread of fluid, and a spherical fluid droplet. The active fluid is modeled by the…

Soft Condensed Matter · Physics 2019-07-22 Harsh Soni , Wan Luo , Robert A. Pelcovits , Thomas Powers

We study the dynamics and phase behaviour of a dry suspension of microtubules and molecular motors. We obtain a set of continuum equations by rigorously coarse graining a microscopic model where motor-induced interactions lead to parallel…

Soft Condensed Matter · Physics 2018-06-27 Ivan Maryshev , Andrew B. Goryachev , Davide Marenduzzo , Alexander Morozov
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