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A relativistic light front treatment of nuclei is developed by performing light front quantization for a chiral Lagrangian. The energy momentum tensor and the appropriate Hamiltonian are obtained. Three illustrations of the formalism are…

Nuclear Theory · Physics 2008-11-26 Gerald A. Miller

The development of the $\beta^-$ based radio-guided surgery aims to extend the technique to those tumours where surgery is the only possible treatment and the assessment of the resection would most profit from the low background around the…

Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

The term 'tomography' is commonly applied to the idea of studying properties of a medium by the modifications this medium induces to a known probe propagating through it. In the context of ultrarelativistic heavy-ion collisions, rare high…

High Energy Physics - Phenomenology · Physics 2008-11-26 Thorsten Renk , Kari J. Eskola

This report presents a design of a gantry for proton therapy based on the concept of adiabatic transition. The use of fixed-field alternating gradient magnets allows a large momentum acceptance and supports fast energy modulation. The…

Accelerator Physics · Physics 2021-05-13 Titus-Stefan Dascalu , Suzanne L. Sheehy

Carbon ion beam radiotherapy enables a very localised dose deposition. However, already small changes in the patient geometry or positioning errors can significantly distort the dose distribution. A live monitoring system of the beam…

The effective use of swift ion beams in cancer treatment (known as hadrontherapy) as well as an appropriate protection in manned space missions rely on the accurate understanding of energy delivery to cells damaging their genetic…

Trapped ions driven by electromagnetic radiation constitute one of the most developed quantum technologies to date. The scenarios range from proof-of-principle experiments to on-chip integration for quantum information units. In most cases,…

Quantum Physics · Physics 2023-09-26 T. Tassis , F. L. Semião

The purpose of this study was to investigate the feasibility of extracting proton beams with two distinct energies within a single synchrotron cycle. The energy difference between the beams should be sufficient to use one beam as a range…

Accelerator Physics · Physics 2025-06-25 Alexander A. Pryanichnikov , Dmitry Shwartz , Jon Feldmand , Joao Seco , Maria Francesca Spadea

Cancer therapy for deep-seated tumors requires precise irradiation of a small target deep within the patient while minimizing radiation exposure to surrounding tissues. This can be accomplished with a round beam sharply converging towards a…

In the past few years a wealth of high quality data has made possible to test current theoretical ideas about the properties of hadrons subject to extreme conditions of density and temperature. The relativistic heavy-ion program carried out…

High Energy Physics - Phenomenology · Physics 2016-11-23 Alejandro Ayala

In its broadest terms, doctoral dissertation entitled "Track structure modelling for ion radiotherapy" is part of the supporting research background in the development of the ambitious proton radiotherapy project currently under way at the…

Medical Physics · Physics 2014-10-21 Marta Korcyl

Nuclear physics experiments are always in need of more and more advanced detection systems. During the last years relevant technological developments have come out with many improvements in terms of performance and compactness of detector…

Instrumentation and Detectors · Physics 2021-01-26 Paolo Finocchiaro

Radiation therapy is a critical component of cancer treatment. However, the delivery of radiation poses inherent challenges, particularly in minimizing radiation exposure to healthy organs surrounding the tumor site. One significant…

Optimization and Control · Mathematics 2024-01-22 Keshav Kumar K. , NVSL Narasimham

The goal of cancer immunotherapy is to boost a patient's immune response to a tumor. Yet, the design of an effective immunotherapy is complicated by various factors, including a potentially immunosuppressive tumor microenvironment,…

Tissues and Organs · Quantitative Biology 2017-06-29 Anna Konstorum , Anthony T. Vella , Adam J. Adler , Reinhard Laubenbacher

In the 21st century, new and alternative non-radioactive methods for cancer treatment have been developed. One of this is magnetic hyperthermia (MH), which is based on the ability of magnetic nanoparticles (MNP) to transduce electromagnetic…

Medical Physics · Physics 2020-07-28 Christian Calvache , Jenny Mera-Córdoba , Diego F. Coral

In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

Medical Physics · Physics 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

Quantum hadrodynamics (QHD) is a framework for describing the nuclear many-body problem as a relativistic system of baryons and mesons. Motivation is given for the utility of such an approach and for the importance of basing it on a local,…

Nuclear Theory · Physics 2014-11-18 Brian D. Serot , John Dirk Walecka

Neutron stars provide a cosmic laboratory to study the nature of dark matter particles and their interactions. Dark matter can be captured by neutron stars via scattering, where kinetic energy is transferred to the star. This can have a…

High Energy Physics - Phenomenology · Physics 2020-09-17 Nicole F. Bell , Giorgio Busoni , Sandra Robles , Michael Virgato