Applications of Raman Spectroscopy in Clinical Medicine
Abstract
Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews recent advances in Raman spectroscopy and its applications in diagnosing various critical diseases, including cancers, infections, and neurodegenerative diseases, and in predicting surgical outcomes. These advances are explored through discussion of state-of-the-art forms of Raman spectroscopy, such as surface-enhanced Raman spectroscopy, resonance Raman spectroscopy, and tip-enhanced Raman spectroscopy employed in biomedical sciences. We discuss biomedical applications, including various aspects and methods of ex vivo and in vivo medical diagnosis, sample collection, data processing, and achievements in realizing the correlation between Raman spectra and biochemical information in certain diseases. Finally, we present the limitations of the current study and provide perspectives for future research.
Keywords
Cite
@article{arxiv.2304.07740,
title = {Applications of Raman Spectroscopy in Clinical Medicine},
author = {Yaping Qi and Esther Xinyi Chen and Dan Hu and Ying Yang and Zhenping Wu and Ming Zheng and Mohammad A. Sadi and Yucheng Jiang and Kang Zhang and Zi Chen and Yong P. Chen},
journal= {arXiv preprint arXiv:2304.07740},
year = {2023}
}