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Radiotherapy represents an important phase of treatment for a large number of cancer patients. It is essential that resources used to deliver this treatment are employed effectively. This paper presents a new integer linear programming…
Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical…
A survey of physics useful to proton radiotherapy, centered on stopping, scattering and hard scatters: 1. Introduction 2. The fundamental formula dose = fluence x mass stopping power. Practical units, comments on effective stopping power.…
This document is one of a series of whitepapers from the USQCD collaboration. Here, we discuss opportunities for lattice QCD calculations related to the structure and spectroscopy of hadrons and nuclei. An overview of recent lattice…
Laser-driven ion acceleration provides ultra-short, high-charge, low-emittance beams, which are desirable for a wide range of high-impact applications. Yet after decades of research, a significant increase in maximum ion energy is still…
Electron capture processes are important in the search for new physics. In this context, a high capture rate is desired. We investigate the possibility of enhancing the electron capture rate by irradiating laser beam to ''atom''. The…
The development of instrumentation for operation in high-radiation environments represents a challenge in various research fields, particularly in particle physics experiments and space missions, and drives an ever-increasing demand for…
Breast cancer research over the last decade has been tremendous. The ground breaking innovations and novel methods help in the early detection, in setting the stages of the therapy and in assessing the response of the patient to the…
Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…
When using superconducting (SC) magnets in a gantry for proton therapy, the gantry will benefit from some reduction in size and a large reduction in weight. In this contribution we show an important additional advantage of SC magnets in…
Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…
Most commercially available treatment planning systems for brachytherapy operate based on physical dose and do not incorporate fractionation or tissue-specific response. The purpose of this study is to investigate the potential for…
Given that there are 94 clinics and more than 200,000 patients treated worldwide, proton and carbon are the most used heavily charged particles in heavy ion therapy. However, there is a recent increasing trend in using new ion beams. Each…
The lack of molecular-level understanding for the electronic excitation response of DNA to charged particle radiation, such as high-energy protons, remains a fundamental scientific bottleneck in advancing proton and other ion beam cancer…
In this work, we propose a novel technique for in-vivo proton therapy range verification. This technique makes use of a small hadron tumour marker, $^{92}$Mo, implanted at a short known distance from the clinical treatment volume. Signals…
FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy by delivering doses with ultra-high dose rates. FLASH-RT has the ability to suppress tumor growth while sparing normal tissues, known as the FLASH effect. Although FLASH effect…
The hadron production in heavy ion collision is treated in the framework of thermodynamic vision. Thermodynamic system formed during central collision of Pb-Pb at high energies is considered, through which binary collision is assumed among…
Hypernuclei, nuclei containing one or more hyperons, serve as unique laboratories for probing the non-perturbative quantum chromodynamics (QCD). Recent progress in hypernuclear physics, driven by advanced experimental techniques and…
A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in treatment planning of radiotherapy with protons and heavier…
We are at the verge of a new impact from hypernuclear experiments planned or already operative at various laboratories all over the world. The complementary of these different experimental approaches to hypernuclei provides a wide basis for…