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Particle accelerators have enabled forefront research in high energy physics and other research areas for more than half a century. Accelerators have directly contributed to 26 Nobel Prizes in Physics since 1939 as well as another 20 Nobel…

Accelerator Physics · Physics 2022-06-20 Javier Resta-López

The theoretical and experimental aspects of particle production from the strong equivalent photon fluxes present at high energy hadron colliders are reviewed. The goal is to show how photons at hadron colliders can improve what we have…

High Energy Physics - Phenomenology · Physics 2010-01-27 Joakim Nystrand

Radioactive ion beams (RIB) are a key focus of current research in nuclear physics. Already long ago it was proposed that they could have applications in cancer therapy. In fact, while charged particle therapy is potentially the most…

In this work, we report on the advantageous aspects of the i-TED Compton imager for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that…

This paper deals with the classic radiotherapy dose fractionation problem for cancer tumors concerning the following goals: a) To maximize the effect of radiation on the tumor, restricting the effect produced to the organs at risk (healing…

Optimization and Control · Mathematics 2021-02-17 Luis Alberto Fernández , Lucía Fernández

Currently, diagnostic medicine uses a multitude of tools ranging from ionising radiation to histology analysis. With advances in piezoelectric crystal technology, high-frequency ultrasound imaging has developed to achieve comparatively high…

Medical Physics · Physics 2022-01-13 Akhil Kallepalli , James Halls , David B. James , Mark A. Richardson

Access to high-energy particle beams is key for testing high-energy physics (HEP) instruments. Accelerators for cancer treatment can serve as such a testing ground. However, HEP instrument tests typically require particle fluxes…

Ultra-high dose rate radiation therapy (FLASH) based on proton irradiation is of major interest for cancer treatments but creates new challenges for dose monitoring. Amorphous hydrogenated silicon is known to be one of the most…

We present a nitrogen-targeting-Proton-Carbon-Alpha-Therapy method, abbreviated as Proton-CAT, which partially converts protons into carbon-12 and $\alpha$ particles through nuclear reactions between protons and nitrogen-15. Monte Carlo…

The area of interests of nuclear physics are studies of reactions, wherein atomic nuclei of projectile collide with target nuclei. An amount of energy lost by projectile nucleus during its passing through the target is a major issue - it is…

Medical Physics · Physics 2018-04-10 Weronika Maliszewska , Przemysław Sękowski , Izabela Skwira-Chalot

Radiotherapy aims to deliver a prescribed dose to the tumor while sparing neighboring organs at risk (OARs). Increasingly complex treatment techniques such as volumetric modulated arc therapy (VMAT), stereotactic radiosurgery (SRS),…

Medical Physics · Physics 2023-10-23 Elahheh Salari , Jing Wang , Jacob Wynne , Chih-Wei Chang , Xiaofeng Yang

The development of instrumentation to be operated in high-radiation environments is one of the main challenges in fundamental research. Besides space and nuclear applications, particle physics experiments also need radiation-hard devices.…

Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities caused by high-dose exposure to critical structures remain a…

It is proposed to treat cancer by the combination of a strong magnetic field with intense ultrasound. At the low electrical conductivity of tissue the magnetic field is not frozen into the tissue, and oscillates against the tissue which is…

General Physics · Physics 2009-06-04 Dr. Friedwardt Winterberg

The $^{10}$B isotope has been almost exclusively used in the neutron-capture radiation therapy (NCT) of cancer for decades. We have identified two other nuclides suitable for the radiotherapy, which have ca.10 times larger cross section of…

Medical Physics · Physics 2019-07-16 V. I. Kukulin , A. V. Bibikov , E. V. Tkalya , M. Ceccarelli , I. V. Bodrenko

The accuracy of hadrontherapy treatment is currently limited by ion-range uncertainties. In order to fully exploit the potential of this technique, we propose the development of a novel system for online control of particle therapy, based…

Proton radiography is a widely-fielded diagnostic used to measure magnetic structures in plasma. The deflection of protons with multi-MeV kinetic energy by the magnetic fields is used to infer their path-integrated field strength. Here, the…

Ion beam analysis techniques are among the most powerful tools for advanced material characterization. Despite their growing relevance in a widening number of fields, most ion beam analysis facilities still rely on the oldest accelerator…

Plasma Physics · Physics 2019-03-06 Matteo Passoni , Luca Fedeli , Francesco Mirani

We propose a series of simulations about the potential use of Boron isotopes to trigger neutron-free (aneutronic) nuclear reactions in cancer cells through the interaction with an incoming energetic proton beam, thus resulting in the…

Medical Physics · Physics 2016-08-25 L. Giuffrida , D. Margarone , G. A. P. Cirrone , A. Picciotto , G. Korn

In this paper, we present the recent progress in the development of a series of gyrotrons at FIR UF that have opened the road to many novel applications in the high-power Terahertz science and technology. The current status of the research…

Instrumentation and Detectors · Physics 2016-11-03 Toshitaka Idehara , Svilen Petrov Sabchevski
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