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In this paper we consider dipole-mediated correlations between DNA and enzymes in the context of their water environment. Such correlations emerge from electric dipole-dipole interactions between aromatic ring structures in DNA and in…

Biological Physics · Physics 2017-02-06 P. Kurian , A. Capolupo , T. J. A. Craddock , G. Vitiello

The electric-field-driven entry process of flexible charged polymers such as single stranded DNA (ssDNA) into asymmetric nanoscale channels such as alpha-hemolysin protein channel is studied theoretically and using molecular dynamics…

Soft Condensed Matter · Physics 2012-02-29 Narges Nikoofard , Hossein Fazli

A relationship between the preexponent of the rate constant and the distribution over activation barrier energies for enzymatic/protein reactions is revealed. We consider an enzyme solution as an ensemble of individual molecules with…

Biomolecules · Quantitative Biology 2012-11-16 A. E. Sitnitsky

This article describes our hypothesis on how transmutations may be induced by solid state effects in a crystalline lattice. We discuss the chemical reaction case, our extension to the nuclear binding case, and a tri-body model of a heavy…

Nuclear Theory · Physics 2020-08-14 Anthony Zuppero , Thomas J. Dolan

Many enzymes appear to diffuse faster in the presence of substrate and to drift either up or down a concentration gradient of their substrate. Observations of these phenomena, termed enhanced enzyme diffusion (EED) and enzyme chemotaxis,…

Chemical Physics · Physics 2019-10-29 Mudong Feng , Michael K. Gilson

Strong influence of water molecules on the transport and magnetic properties of DNA, observed in this study, opens up real opportunities for application of DNA in molecular electronics. Interaction of the nucleobases with water molecules…

Chemical Physics · Physics 2010-08-13 Julia Berashevich , Tapash Chakraborty

Proton-coupled electron transfer (PCET) is the underlying mechanism governing important reactions ranging from water splitting in photosynthesis to oxygen reduction in hydrogen fuel cells. The interplay of proton and electronic charge…

Chemical Physics · Physics 2023-09-12 Micheline B. Soley , Pablo E. Videla , Erik T. J. Nibbering , Victor S. Batista

In this work, we present a paradigm bridging electromagnetic (EM) and molecular communication through a stimuli-responsive intra-body model. It has been established that protein molecules, which play a key role in governing cell behavior,…

Molecular Networks · Quantitative Biology 2020-09-03 Hadeel Elayan , Andrew W. Eckford , Raviraj Adve

Transport of molecules across membrane channels is investigated theoretically using exactly solvable discrete stochastic site-binding models. It is shown that the interaction potential between molecules and the channel has a strong effect…

Soft Condensed Matter · Physics 2009-11-11 Anatoly B. Kolomeisky

We investigate diffusion-limited reactions between a diffusing particle and a target site on a semiflexible polymer, a key factor determining the kinetics of DNA-protein binding and polymerization of cytoskeletal filaments. Our theory…

Soft Condensed Matter · Physics 2010-12-08 Yann von Hansen , Roland R. Netz , Michael Hinczewski

Proton transfer is ubiquitous in many fundamental chemical and biological processes, and the ability to modulate and control the proton transfer rate would have a major impact on numerous quantum technological advances. One possibility to…

Chemical Physics · Physics 2021-12-07 Fabijan Pavošević , Sharon Hammes-Schiffer , Angel Rubio , Johannes Flick

Folding of proteins into their correct native structure is key to their function. Simultaneously, the intricate interplay between cell movement and protein conformation highlights the complex nature of cellular processes. In this work, we…

Molecular Networks · Quantitative Biology 2023-10-24 Hadeel Elayan , Andrew W. Eckford , Raviraj Adve

The three-dimensional organization of chromatin is thought to play an important role in controlling gene expression. Specificity in expression is achieved through the interaction of transcription factors and other nuclear proteins with…

Biological Physics · Physics 2025-07-22 Mason N. Rouches , Benjamin B. Machta

Quasi-static models of barrier suppression have played a major role in our understanding of the ionization of atoms and molecules in strong laser fields. Despite their success, in the case of diatomic molecules these studies have so far…

Atomic Physics · Physics 2009-11-10 T. Bartsch , T. Uzer

Scattering or tunneling of an electron at a potential barrier is a fundamental quantum effect. Electron-electron interactions often affect the scattering, and understanding of the interaction effect is crucial in detection of various…

Mesoscale and Nanoscale Physics · Physics 2022-11-10 Sungguen Ryu , H. -S. Sim

Protonation of DNA basepairs is a reversible phenomenon which can be controlled by tuning the pH of the system. Under mild acidic conditions, the hydrogen bonding pattern of the DNA basepairs undergoes a change. We study the effect of…

Materials Science · Physics 2007-07-31 Sairam S. Mallajosyula , Swapan K Pati

Despite the spontaneity of some in vitro protein folding reactions, native folding in vivo often requires the participation of barrel-shaped multimeric complexes known as chaperonins. Although it has long been known that chaperonin…

Biomolecules · Quantitative Biology 2009-11-13 Jeremy L. England , Vijay S. Pande

Charged particles can be accelerated to high energies by collisionless shock waves in astrophysical environments, such as supernova remnants. By interacting with the magnetized ambient medium, these shocks can transfer energy to particles.…

The ultimate active constituents of the living medium, membranes, ions and molecules, are at the level of the nanometer. Their interactions thus require a quantum processing. The characteristic Action A, linked to the "quantum objects" :…

Biological Physics · Physics 2009-02-18 J. Breton , V. Breton

The nuclear tunneling crossover temperature ($T_c$) of hydrogen transfer reactions in supported molecular-switch architectures can lie close to room temperature. This calls for the inclusion of nuclear quantum effects (NQE) in the…

Chemical Physics · Physics 2020-11-25 Yair Litman , Mariana Rossi
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