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Hydroxide ion transport in anion-exchange membranes fundamentally limits the efficiency of alkaline water electrolysis for green hydrogen production, yet the atomic-scale transport mechanisms remain poorly understood due to the…

Water is a key ingredient for life and plays a central role as solvent in many biochemical reactions. However, the intrinsically quantum nature of the hydrogen nucleus, revealing itself in a large variety of physical manifestations,…

Hydrogen addition and abstraction reactions play an important role as surface reactions in the buildup of complex organic molecules in the dense interstellar medium. Addition reactions allow unsaturated bonds to be fully hydrogenated, while…

Astrophysics of Galaxies · Physics 2018-09-19 V. Zaverkin , T. Lamberts , M. N. Markmeyer , J. Kästner

A novel mechanism for switching a molecular junction based on a proton transfer reaction triggered by an external electrostatic field is proposed. As a specific example to demonstrate the feasibility of the mechanism, the tautomers…

Mesoscale and Nanoscale Physics · Physics 2014-04-18 C. Hofmeister , R. Härtle , O. Rubio-Pons , P. B. Coto , A. L. Sobolewski , M. Thoss

We develop an analytical theory that accounts for the image and surface charge interactions between a charged dielectric membrane and a DNA molecule translocating through the membrane. Translocation events through neutral carbon-based…

Soft Condensed Matter · Physics 2016-08-03 Sahin Buyukdagli , T. Ala-Nissila

Chemical reactions involve the movement of charges, and this work presents a mathematical model for describing chemical reactions in electrolytes. The model is developed using an energy variational method that aligns with classical…

Chemical Physics · Physics 2023-11-02 Shixin Xu , Robert Eisenberg , Zilong Song , Huaxiong Huang

The mechanism of cold- and pressure-denaturation are matter of debate. Some models propose that when denaturation occurs more hydrogen bonds between the molecules of hydration water are formed. Other models identify the cause in the density…

Biological Physics · Physics 2010-11-17 Valentino Bianco , Svilen Iskrov , Giancarlo Franzese

The screening effects by bound target electrons in low energy nuclear reactions in laboratory experiments can be well represented in terms of a constant shift of the tunneling potential barrier as postulated in all previous analyses if the…

Nuclear Theory · Physics 2007-05-23 Noboru Takigawa , Sachie Kimura , David M. Brink

An effective Hamiltonian is considered for hydrogen bonding between two molecules due to the quantum mechanical interaction between the orbitals of the H-atom and the donor and acceptor atoms in the molecules. The Hamiltonian acts on two…

Chemical Physics · Physics 2012-04-03 Ross H. McKenzie

Despite widespread interest, a detailed understanding of the dynamics of proton transfer at interfaces is lacking. Here we use ab initio molecular dynamics to unravel the connection between interfacial water structure and proton transfer…

Materials Science · Physics 2014-03-12 Gabriele Tocci , Angelos Michaelides

The problem of the helix-coil transition of biopolymers in explicit solvents, like water, with the ability for hydrogen bonding with solvent is addressed analytically using a suitably modified version of the Generalized Model of Polypeptide…

Post-transductional modifications tune the functions of proteins and regulate the collective dynamics of biochemical networks that determine how cells respond to environmental signals. For example, protein phosphorylation and nitrosylation…

Cell Behavior · Quantitative Biology 2009-11-13 Roberto Chignola , Chiara Dalla Pellegrina , Alessio Del Fabbro , Edoardo Milotti

In the framework of a quasi-molecular approach, the formation of hydrogen atom in the pre-recombination period of evolution of the universe is analysed quantitatively. Calculations in an adiabatic multi-level representation enable estimates…

Atomic Physics · Physics 2020-12-02 Tamaz Kereselidze , Irakli Noselidze , John F. Ogilvie

The basal plane of graphene can function as a selective barrier that is permeable to protons but impermeable to all ions and gases, stimulating its use in applications such as membranes, catalysis and isotope separation. Protons can…

In living cells, protein-rich condensates can wet the cell membrane and surfaces of membrane-bound organelles. Interestingly, many phase-separating proteins also bind to membranes leading to a molecular layer of bound molecules. Here we…

Biological Physics · Physics 2022-03-22 Xueping Zhao , Giacomo Bartolucci , Alf Honigmann , Frank Jülicher , Christoph A. Weber

Cells accomplish diverse functions using the same molecular building blocks, from setting up cytoplasmic flows to generating mechanical forces. In particular, transitions between these non-equilibrium states are triggered by regulating the…

Soft Condensed Matter · Physics 2022-01-03 Bibi Najma , Minu Varghese , Lev Tsidilkovski , Linnea Lemma , Aparna Baskaran , Guillaume Duclos

Switch-like motifs are among the basic building blocks of biochemical networks. A common motif that can serve as an ultrasensitive switch consists of two enzymes acting antagonistically on a substrate, one making and the other removing a…

Molecular Networks · Quantitative Biology 2023-05-31 Jeremy A. Owen , Pranay Talla , John W. Biddle , Jeremy Gunawardena

Polymer translocation experiments typically involve anionic polyelectrolytes such as DNA molecules driven through negatively charged nanopores. Quantitative modelling of polymer capture to the nanopore followed by translocation therefore…

Soft Condensed Matter · Physics 2017-10-11 Sahin Buyukdagli , Tapio Ala-Nissila

Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for…

Biological Physics · Physics 2021-04-07 Jaime Agudo-Canalejo , Pierre Illien , Ramin Golestanian

Hydrogen bonds are a common feature in protein folding and aggregation. Due to their chemical peculiarities in terms of strength and directionality, a particular attention must be paid to the definition of the hydrogen bond potential…

Biomolecules · Quantitative Biology 2012-08-13 Marta Enciso