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The structural properties of a linear polymer and its evolution in time have a strong bearing on its anisotropic stress response. The mean-square bond length and mean bond angle are the critical parameters that influence the time-varying…

Soft Condensed Matter · Physics 2010-12-30 Prashant Kumar Srivastava , Kartik Venkatraman

Effect of molecular crowding and confinement experienced by protein in the cell during unfolding has been studied by modeling a linear polymer chain on a percolation cluster. It is known that internal structure of the cell changes in time,…

Soft Condensed Matter · Physics 2015-05-14 Amit Raj Singh , Debaprasad Giri , Sanjay Kumar

We study the mechanical stiffening behavior in two-dimensional (2D) cross-linked networks of semiflexible biopolymer filaments under simple shear. Filamental constituents immersed in a fluid undergo thermally excited bending motions.…

Biological Physics · Physics 2007-05-23 T. Van Dillen , P. R. Onck , E. Van der Giessen

We describe some recent results concerning the statistical properties of a self-interacting polymer stretched by an external force. We concentrate mainly on the cases of purely attractive or purely repulsive self-interactions, but our…

Probability · Mathematics 2011-08-25 Dmitry Ioffe , Yvan Velenik

Using a coarse-grained bead-spring model for semi-flexible macromolecules forming a polymer brush, structure and dynamics of the polymers is investigated, varying chain stiffness and grafting density. The anchoring condition for the grafted…

Soft Condensed Matter · Physics 2014-01-28 Andrey Milchev , Kurt Binder

Force induced stretching of polymers is important in a variety of contexts. We have used theory and simulations to describe the response of homopolymers, with $N$ monomers, to force ($f$) in good and poor solvents. In good solvents and for…

Soft Condensed Matter · Physics 2009-11-13 Greg Morrison , Changbong Hyeon , N. M. Toan , Bae-Yeun Ha , D. Thirumalai

The critical incompatibility of polymers with different compositions scales inversely with their length. For instance, a mixture of A and B homopolymers of length $N$ segregates at $\chi_{AB}^{cr} = 2/N$. But what if the difference between…

Soft Condensed Matter · Physics 2026-02-06 Artem M. Rumyantsev , Alexey A. Gavrilov

Here, we provide an overview of theoretical approaches to semiflexible polymers and their networks. Such semiflexible polymers have large bending rigidities that can compete with the entropic tendency of a chain to crumple up into a random…

Soft Condensed Matter · Physics 2016-05-25 Chase P. Broedersz , Fred. C. MacKintosh

We present a theoretical description of the dynamics of a semi-flexible polymer being pulled through a nanopore by an external force acting at the pore. Our theory is based on the tensile blob picture of Pincus in which the front of the…

Statistical Mechanics · Physics 2015-09-16 Pui-Man Lam , Yi Zhen

We analyse the nature of the confinement of an infinitely long (and finite) linear semiflexible homo-polymer chain confined in between two geometrical constraints (A&B) under good solvent condition in two dimensions. The constraints are…

Soft Condensed Matter · Physics 2017-10-16 Pramod Kumar Mishra

The conformational properties of flexible and semiflexible polymers exposed to active noise are studied theoretically. The noise may originate from the interaction of the polymer with surround- ing active (Brownian) particles or from the…

Soft Condensed Matter · Physics 2024-06-03 Thomas Eisenstecken , Gerhard Gompper , Roland G. Winkler

DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of the double helix. In fact the persistence length obtained by…

Soft Condensed Matter · Physics 2009-10-30 Philip Nelson

The nonequilibrium structural and dynamical properties of semiflexible active polar polymers subject to linear flow are studied by numerical simulations. Filaments are confined in two dimensions and immersed in a fluid described by the…

Soft Condensed Matter · Physics 2026-04-23 A. Lamura , R. G. Winkler

The folding transition of biopolymers from the coil to compact structures has attracted wide research interest in the past and is well studied in polymer physics. Recent seminal works on DNA in confined devices have shown that these long…

Soft Condensed Matter · Physics 2023-08-09 Keerthi Radhakrishnan , Sunil P. Singh

The shape of biological shells, such as cell nuclei, membranes, and vesicles, often deviates from a perfect sphere due to an interplay of complex interactions with a myriad of molecular structures. In particular, semiflexible biopolymers…

Soft Condensed Matter · Physics 2025-09-05 Hadiya Abdul Hameed , Jaroslaw Paturej , Aykut Erbas

We consider an inextensible, semiflexible polymer or worm-like chain which is confined in the transverse direction by a parabolic potential and subject to a longitudinal force at the ends, so that the polymer is stretched out and…

Soft Condensed Matter · Physics 2015-05-28 Theodore W. Burkhardt

Biopolymers are characterized by heterogeneous interactions, and usually perform their biological tasks forming contacts within domains of limited size. Combining polymer theory with a replica approach, we study the scaling properties of…

Biomolecules · Quantitative Biology 2015-08-05 Guido Tiana

Effects of sequence disorder on looping and cyclization of the double-stranded DNA are studied theoretically. Both random intrinsic curvature and inhomogeneous bending rigidity are found to result in a remarkably wide distribution of…

Soft Condensed Matter · Physics 2013-05-29 Yuri O. Popov , Alexei V. Tkachenko

Active processes in living systems generate nonequilibrium forces that deform embedded passive macromolecules. To understand how such dynamics influence polymer conformation, we study a flexible passive chain in an active nematic fluid.…

Soft Condensed Matter · Physics 2025-09-30 Zahra K. Valei , Davide Marenduzzo , Tyler N. Shendruk

Stretching an elastic material along one axis typically induces contraction along the transverse axes, a phenomenon known as the Poisson effect. From these strains, one can compute the specific volume, which generally either increases or,…

Soft Condensed Matter · Physics 2024-07-31 Jordan L. Shivers , Fred C. MacKintosh