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The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…

Disordered Systems and Neural Networks · Physics 2022-08-03 Merav Stern , Nicolae Istrate , Luca Mazzucato

Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

Time perception - how humans and animals perceive the passage of time - forms the basis for important cognitive skills such as decision-making, planning, and communication. In this work, we propose a framework for examining the mechanisms…

Systems and Control · Electrical Eng. & Systems 2023-11-08 Inês Lourenço , Robert Mattila , Rodrigo Ventura , Bo Wahlberg

Posttranslational modifications (PTMs) are an integral component to how cells respond to perturbation. While experimental advances have enabled improved PTM identification capabilities, the same throughput for characterizing how structural…

Biomolecules · Quantitative Biology 2022-11-23 Austin T. Weigle , Jiangyan Feng , Diwakar Shukla

The motion of membranes interacting with external fields in space-times with curvature and torsion is considered. The intrinsic and extrinsic properties of the immersion are fused together to form a stress tensor for the corresponding…

General Relativity and Quantum Cosmology · Physics 2019-10-15 Özgür Açık , Aytolun Çatalkaya , Ümit Ertem , Özgün Sütemen

Membrane configurations in the Banks-Fischler-Shenker-Susskind matrix model are unstable due to the existence of flat directions in the potential and the decay process can be seen as a realization of chaotic scattering. In this note, we…

High Energy Physics - Theory · Physics 2025-05-14 Osamu Fukushima , Tomohiro Shigemura , Kentaroh Yoshida

Scattering wave systems that are periodically modulated in time offer many new degrees of freedom to control waves both in spatial and frequency domains. Such systems, albeit linear, do not conserve frequency and require the adaptation of…

Applied Physics · Physics 2023-04-25 Matthieu Malléjac , Romain Fleury

Human close-range proximity interactions are the key determinant for spreading processes like knowledge diffusion, norm adoption, and infectious disease transmission. These dynamical processes can be modeled with time-respecting paths on…

Physics and Society · Physics 2026-05-28 Silvia Guerrini , Ciro Cattuto , Lorenzo Dall'Amico

Many biological, social and man-made systems are better described in terms of temporal networks, i.e. networks whose links are only present at certain points in time, rather than by static ones. In particular, it has been found that…

Physics and Society · Physics 2019-05-22 Oliver E. Williams , Fabrizio Lillo , Vito Latora

Mathematical models of the real world are simplified representations of complex systems. A caveat to using mathematical models is that predicted causal effects and conditional independences may not be robust under model extensions, limiting…

Methodology · Statistics 2022-08-30 Tineke Blom , Joris M. Mooij

In this paper we present a model for the lifetime of wireless sensor networks. The model takes into consideration several parameters such as the total number of sensors, network size, percentage of sink nodes, location of sensors, the…

Networking and Internet Architecture · Computer Science 2012-01-12 Abdelrahman Elleithy , Gonhsin Liu

The interaction between nano- or micro-sized particles and cell membranes is of crucial importance in many biological and biomedical applications such as drug and gene delivery to cells and tissues. During their cellular uptake, the…

Temporal networks are widely used models for describing the architecture of complex systems. Network memory -- that is the dependence of a temporal network's structure on its past -- has been shown to play a prominent role in diffusion,…

Physics and Society · Physics 2020-04-28 Oliver E. Williams , Lucas Lacasa , Ana P. Millán , Vito Latora

Topological phases of matter are ubiquitous in crystals, but less is known about their existence in amorphous systems, that lack long-range order. In this perspective, we review the recent progress made on theoretically defining amorphous…

Mesoscale and Nanoscale Physics · Physics 2023-03-30 Paul Corbae , Julia D. Hannukainen , Quentin Marsal , Daniel Muñoz-Segovia , Adolfo G. Grushin

This paper presents novel controllers that yield finite-time stability for linear systems. We first present a sufficient condition for the origin of a scalar system to be finite-time stable. Then we present novel finite-time controllers…

Dynamical Systems · Mathematics 2021-06-11 Kunal Garg , Dimitra Panagou

Together with the concept of reversibility, another relevant physical notion is time-symmetry, which expresses that there is no way of distinguishing between backward and forward time directions. This notion, found in physical theories, has…

Discrete Mathematics · Computer Science 2010-12-08 Andrés Moreira , Anahi Gajardo

Automated verification of living organism models allows us to gain previously unknown knowledge about underlying biological processes. In this paper, we show the benefits to use parametric time Petri nets in order to analyze precisely the…

Logic in Computer Science · Computer Science 2015-06-23 Alexander Andreychenko , Morgan Magnin , Katsumi Inoue

Cellular tissue behavior is a multiscale problem. At the cell level, out of equilibrium, biochemical reactions drive physical cell-cell interactions in a typical active matter process. Cell modeling computer simulations are a robust tool to…

Soft Condensed Matter · Physics 2021-02-09 Emanuel F. Teixeira , Heitor C. M. Fernandes , Leonardo G. Brunnet

Studying systems where many individual bodies in motion interact with one another is a complex and interesting area. Simple mechanisms that may be determined for biological, chemical, or physical reasons can lead to astonishingly complex…

Quantitative Methods · Quantitative Biology 2023-01-03 Cameron McNamee , Renee Reijo Pera

Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they…

Molecular Networks · Quantitative Biology 2016-06-22 Michele Monti , Pieter Rein ten Wolde