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The global dynamics of gene regulatory networks are known to show robustness to perturbations in the form of intrinsic and extrinsic noise, as well as mutations of individual genes. One molecular mechanism underlying this robustness has…

Molecular Networks · Quantitative Biology 2015-06-15 Claus Kadelka , David Murrugarra , Reinhard Laubenbacher

Oscillations in a stochastic dynamical system, whose deterministic counterpart has a stable steady state, are a widely reported phenomenon. Traditional methods of finding parameter regimes for stochastically-driven resonances are, however,…

Molecular Networks · Quantitative Biology 2017-03-01 Michael F Adamer , Thomas E Woolley , Heather A Harrington

Research of delayed neural networks with variable self-inhibitions, inter-connection weights, and inputs is an important issue. %In the real world, self-inhibitions, %inter-connection weights, and inputs should vary through time. In In this…

Dynamical Systems · Mathematics 2007-05-23 Wenlian Lu , Tianping Chen

Rate processes are simple and analytically tractable models for many dynamical systems which switch stochastically between a discrete set of quasi stationary states but they may also approximate continuous processes by coarse grained,…

Statistical Mechanics · Physics 2013-03-11 R. Toenjes , H. Kori

Optomechanical systems are known to exhibit a rich set of complex dynamical features including various types of chaotic behavior and multi-stability. Although this exotic behavior has attracted an intense research interest, the utilization…

Chaotic Dynamics · Physics 2021-05-19 S. Christou , V. Kovanis , A. E. Giannakopoulos , Y. Kominis

We consider the dynamics of a population of organisms containing two mutually inhibitory gene regulatory networks, that can result in a bistable switch-like behaviour. We completely characterize their local and global dynamics in the…

Molecular Networks · Quantitative Biology 2016-10-07 Michael C. Mackey , Marta Tyran-Kaminska

Superoscillations, i.e., the phenomenon that a bandlimited function can temporary oscillate faster than its highest Fourier component, are being much discussed for their potential for `superresolution' beyond the diffraction limit. Here, we…

Quantum Physics · Physics 2015-10-16 Achim Kempf , Angus Prain

Oscillatory behavior is ubiquitous in many natural and engineered systems, often emerging through self-regulating mechanisms. In this paper, we address the challenge of stabilizing a desired oscillatory pattern in a networked system where…

Systems and Control · Electrical Eng. & Systems 2025-02-05 Luis Guillermo Venegas-Pineda , Hildeberto Jardón-Kojakhmetov , Ming Cao

Bistable biochemical switches are ubiquitous in gene regulatory networks and signal transduction pathways. Their switching dynamics, however, are difficult to study directly in experiments or conventional computer simulations, because…

Molecular Networks · Quantitative Biology 2009-11-10 Rosalind J. Allen , Patrick B. Warren , Pieter Rein ten Wolde

A stochastic reaction-diffusion model is studied on a networked support. In each patch of the network two species are assumed to interact following a non-normal reaction scheme. When the interaction unit is replicated on a directed linear…

We investigate the relaxation dynamics of a single artificial atom interacting, via multiple coupling points, with a continuum of bosonic modes (photons or phonons) in a one-dimensional waveguide. In the non-Markovian regime, where the…

Quantum Physics · Physics 2020-10-07 Lingzhen Guo , Anton Frisk Kockum , Florian Marquardt , Göran Johansson

We study the noise characteristics of stochastic oscillations in protein number dynamics of simple genetic oscillatory systems. Using the three-component negative feedback transcription regulatory system called the repressilator as a…

Molecular Networks · Quantitative Biology 2015-03-13 Byungjoon Min , K. -I. Goh , I. -M. Kim

In networked systems, stochastic resonance occurs as a collective phenomenon where the entire stochastic network resonates with a weak applied periodic signal. Beyond the interplay among the network coupling, the amplitude of the external…

Adaptation and Self-Organizing Systems · Physics 2025-02-11 Jonah E. Friederich , Everton S. Medeiros , Sabine H. L. Klapp , Anna Zakharova

Additive noise is known to produce counter-intuitive behaviors in nonlinear dynamical systems. Previously, it was shown that systems with a deterministic limit cycle can display bistable switching between metastable states in the presence…

Chaotic Dynamics · Physics 2015-01-26 Michael A. Schwemmer , Jay M. Newby

A one-dimensional dynamical system with a marginal quasiperiodic gradient is presented as a mathematical extension of a nonuniform oscillator. The system exhibits a nonchaotic stagnant motion, which is reminiscent of intermittent chaos. In…

Chaotic Dynamics · Physics 2008-08-25 Takahito Mitsui

Self-oscillations are the result of an efficient mechanism generating periodic motion from a constant power source. In quantum devices, these oscillations may arise due to the interaction between single electron dynamics and mechanical…

We examine microscopic mechanisms for coupling stochastic oscillators so that they display similar and correlated temporal variations. Unlike oscillatory motion in deterministic dynamical systems, complete synchronization of stochastic…

Quantitative Methods · Quantitative Biology 2009-09-29 Amitabha Nandi , G. Santhosh , R. K. Brojen Singh , Ram Ramaswamy

Problems with artificial neural networks originate from their deterministic nature and inevitable prior learnings, resulting in inadequate adaptability against unpredictable, abrupt environmental change. Here we show that a stochastically…

Disordered Systems and Neural Networks · Physics 2009-11-13 Naoki Asakawa , Yasushi Hotta , Teruo Kanki , Hitoshi Tabata , Tomoji Kawai

This article studies stochastic relative phase stability, i.e., stochastic phase-cohesiveness, of discrete-time phase-coupled oscillators. Stochastic phase-cohesiveness in two types of networks is studied. First, we consider oscillators…

Systems and Control · Electrical Eng. & Systems 2023-08-10 Matin Jafarian , Mohammad H. Mamduhi , Karl H. Johansson

The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule…

Biological Physics · Physics 2014-06-12 Jay Newby