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We analyze general two-species stochastic models, of the kind generally used for the study of population dynamics. We show that the conditions for the stochastic (microscopic) model to display approximate sustained oscillatory behavior are…

Populations and Evolution · Quantitative Biology 2016-08-14 Sebastián Risau-Gusman , Guillermo Abramson

In a stochastic process, noise often modifies the picture offered by the mean field dynamics. In particular, when there is an absorbing state, the noise erases a stable fixed point of the mean field equation from the stationary…

Statistical Mechanics · Physics 2018-12-19 JaeJun Lee , Julian Lee

We revisit the dynamics of a gene repressed by its own protein in the case where the transcription rate does not adapt instantaneously to protein concentration but is a dynamical variable. We derive analytical criteria for the appearance of…

Quantitative Methods · Quantitative Biology 2009-02-19 Pierre-Emmanuel Morant , Quentin Thommen , François Lemaire , Constant Vandermoëre , Benjamin Parent , Marc Lefranc

An important occurrence in many cellular contexts is the crossing of a prescribed threshold by a regulatory protein. The timing of such events is stochastic as a consequence of the innate randomness in gene expression. A question of…

Molecular Networks · Quantitative Biology 2017-02-24 Khem Raj Ghusinga , Abhyudai Singh

We analyse the effect of intrinsic fluctuations on the properties of bistable stochastic systems with time scale separation operating under1 quasi-steady state conditions. We first formulate a stochastic generalisation of the quasi-steady…

Biological Physics · Physics 2016-03-02 Roberto de la Cruz , Pilar Guerrero , Fabian Spill , Tomás Alarcón

Stochastic resonance holds much promise for the detection of weak signals in the presence of relatively loud noise. Following the discovery of nondynamical and of aperiodic stochastic resonance, it was recently shown that the phenomenon can…

Condensed Matter · Physics 2009-10-31 Redouane Fakir

An oscillator with stochastic frequency is discussed as a model for evaluating the quantum coherence properties of a physical system. It is found that the choice of jump statistics has to be considered with care if unphysical consequences…

Quantum Physics · Physics 2009-10-31 Martti Havukainen , Stig Stenholm

Ring topologies of repressing genes have qualitatively different long-term dynamics if the number of genes is odd (they oscillate) or even (they exhibit bistability). However, these attractors may not fully explain the observed behavior in…

Molecular Networks · Quantitative Biology 2010-01-22 Natalja Strelkowa , Mauricio Barahona

Gene regulatory dynamics is governed by molecular processes and therefore exhibits an inherent stochasticity. However, for the survival of an organism it is a strict necessity that this intrinsic noise does not prevent robust functioning of…

Molecular Networks · Quantitative Biology 2007-05-23 Stefan Braunewell , Stefan Bornholdt

We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this…

Molecular Networks · Quantitative Biology 2016-12-21 Alan Veliz-Cuba , Chinmaya Gupta , Matthew R. Bennett , Krešimir Josić , William Ott

We show that the dipole, a system usually proposed to model relaxation phenomena, exhibits a maximum in the signal-to-noise ratio at a non-zero noise level, thus indicating the appearance of stochastic resonance. The phenomenon occurs in…

Condensed Matter · Physics 2016-08-15 J. M. G. Vilar , A. Pérez-Madrid , J. M. Rubí

In biochemical signaling, information is often encoded in oscillatory signals. However, the advantages of such a coding strategy over an amplitude encoding scheme of constant signals remain unclear. Here we study the dynamics of a simple…

Subcellular Processes · Quantitative Biology 2012-03-09 Filipe Tostevin , Wiet de Ronde , Pieter Rein ten Wolde

A nonlinear oscillator with an abruptly inhomogeneous restoring force driven by an uniform oscillating force exhibits stochastic properties under specific resonance conditions. This behaviour elucidates the elementary mechanism of the…

Plasma Physics · Physics 2015-05-19 S. V. Bulanov , A. Yogo , T. Zh. Esirkepov , J. K. Koga , S. S. Bulanov , K. Kondo , M. Kando

We consider incoherent excitation of multilevel quantum systems, e.g. molecules with multiple vibronic states. We show that (1) the geometric constraints of the matter-field coupling operator guarantee that noise-induced coherences will be…

Quantum Physics · Physics 2023-10-02 Amro Dodin , Timur V. Tscherbul , Paul Brumer

Stochastic resonance shows that under some circumstances noise can enhance the response of a system to a periodic force. While this effect has been extensively investigated theoretically and demonstrated experimentally in classical systems,…

Quantum Physics · Physics 2009-11-06 S. F. Huelga , M. B. Plenio

At an optimal value of the noise intensity, the maximum variability in rebound burst durations is observed and referred to as a response stochastic incoherence. A general mechanism underlying this phenomenon is given, being different from…

Biological Physics · Physics 2010-03-23 Marzena Ciszak

Bistable biological regulatory systems need to cope with stochastic noise to fine-tune their function close to bifurcation points. Here, we study stability properties of this regime in generic systems to demonstrate that cooperative…

Adaptation and Self-Organizing Systems · Physics 2025-08-04 Daniele Proverbio , Arthur N. Montanari , Alexander Skupin , Jorge Gonçalves

Molecular noise in gene regulatory networks has two intrinsic components, one part being due to fluctuations caused by the birth and death of protein or mRNA molecules which are often present in small numbers and the other part arising from…

Molecular Networks · Quantitative Biology 2015-11-17 Davit A. Potoyan , Peter G. Wolynes

Collective electron transport causes a weakly coupled semiconductor superlattice under dc voltage bias to be an excitable system with $2N+2$ degrees of freedom: electron densities and fields at $N$ superlattice periods plus the total…

Mesoscale and Nanoscale Physics · Physics 2020-11-19 Emanuel Mompo , Miguel Ruiz Garcia , Manuel Carretero , Holger T. Grahn , Yaohui Zhang , Luis L. Bonilla

Nature presents multiple intriguing examples of processes which proceed at high precision and regularity. This remarkable stability is frequently counter to modelers' experience with the inherent stochasticity of chemical reactions in the…

Molecular Networks · Quantitative Biology 2015-12-31 Andreas Milias-Argeitis , Stefan Engblom , Pavol Bauer , Mustafa Khammash