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Related papers: Shapes of RNA pseudoknot structures

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In this paper we study $k$-noncrossing, canonical RNA pseudoknot structures with minimum arc-length $\ge 4$. Let ${\sf T}_{k,\sigma}^{[4]} (n)$ denote the number of these structures. We derive exact enumeration results by computing the…

Combinatorics · Mathematics 2008-06-17 Gang Ma , Christian M. Reidys

In this paper we derive the generating function of RNA structures with pseudoknots. We enumerate all $k$-noncrossing RNA pseudoknot structures categorized by their maximal sets of mutually intersecting arcs. In addition we enumerate…

Combinatorics · Mathematics 2009-09-29 Emma Y. Jin , Jing Qin , Christian M. Reidys

In this paper we present the asymptotic enumeration of RNA structures with pseudoknots. We develop a general framework for the computation of exponential growth rate and the sub exponential factors for $k$-noncrossing RNA structures. Our…

Biomolecules · Quantitative Biology 2009-09-29 Emma Y. Jin , Christian M. Reidys

In this paper we study $k$-noncrossing RNA structures with minimum arc-length 4 and at most $k-1$ mutually crossing bonds. Let ${\sf T}_{k}^{[4]}(n)$ denote the number of $k$-noncrossing RNA structures with arc-length $\ge 4$ over $n$…

Combinatorics · Mathematics 2008-07-04 Hillary S. W. Han , Christian M. Reidys

A k-noncrossing RNA pseudoknot structure is a graph over $\{1,...,n\}$ without 1-arcs, i.e. arcs of the form (i,i+1) and in which there exists no k-set of mutually intersecting arcs. In particular, RNA secondary structures are 2-noncrossing…

Combinatorics · Mathematics 2007-08-01 Emma Y. Jin , Christian M. Reidys

In this paper we study the distribution of stacks in $k$-noncrossing, $\tau$-canonical RNA pseudoknot structures ($<k,\tau> $-structures). An RNA structure is called $k$-noncrossing if it has no more than $k-1$ mutually crossing arcs and…

Combinatorics · Mathematics 2008-07-08 Hillary S. W. Han , Christian M. Reidys

In this paper we enumerate $k$-noncrossing RNA pseudoknot structures with given minimum arc- and stack-length. That is, we study the numbers of RNA pseudoknot structures with arc-length $\ge 3$, stack-length $\ge \sigma$ and in which there…

Biomolecules · Quantitative Biology 2007-12-04 Emma Y. Jin , Christian M. Reidys

In this paper we compute the limit distributions of the numbers of hairpin-loops, interior-loops and bulges in k-noncrossing RNA structures. The latter are coarse grained RNA structures allowing for cross-serial interactions, subject to the…

Combinatorics · Mathematics 2009-12-03 Markus E. Nebel , Christian M. Reidys , Rita R. Wang

There exists many complicated $k$-noncrossing pseudoknot RNA structures in nature based on some special conditions. The special characteristic of RNA structures gives us great challenges in researching the enumeration, prediction and the…

Combinatorics · Mathematics 2020-11-23 Yangyang Zhao

In this paper we study properties of topological RNA structures, i.e.~RNA contact structures with cross-serial interactions that are filtered by their topological genus. RNA secondary structures within this framework are topological…

Combinatorics · Mathematics 2016-06-23 Thomas J. X. Li , Christian M. Reidys

In this paper we study $k$-noncrossing RNA structures with arc-length $\ge 3$, i.e. RNA molecules in which for any $i$, the nucleotides labeled $i$ and $i+j$ ($j=1,2$) cannot form a bond and in which there are at most $k-1$ mutually…

Combinatorics · Mathematics 2007-08-24 Emma Y. Jin , Christian M. Reidys

In this paper we present a selfcontained analysis and description of the novel {\it ab initio} folding algorithm {\sf cross}, which generates the minimum free energy (mfe), 3-noncrossing, $\sigma$-canonical RNA structure. Here an RNA…

Combinatorics · Mathematics 2008-09-30 Fenix W. D. Huang , Wade W. J. Peng , Christian M. Reidys

We consider a certain abstract of RNA secondary structures, which is closely related to RNA shapes. The generating function counting the number of the abstract structures is obtained by means of Narayana numbers and 2-Motzkin paths, through…

Combinatorics · Mathematics 2019-07-18 Sang Kwan Choi

In this paper we enumerate $k$-noncrossing RNA pseudoknot structures with given minimum stack-length. We show that the numbers of $k$-noncrossing structures without isolated base pairs are significantly smaller than the number of all…

Biomolecules · Quantitative Biology 2007-12-04 Emma Y. Jin , Christian M. Reidys

Computational prediction of RNA structures is an important problem in computational structural biology. Studies of RNA structure formation often assume that the process starts from a fully synthesized sequence. Experimental evidence,…

Biomolecules · Quantitative Biology 2021-04-28 Vo Hong Thanh , Dani Korpela , Pekka Orponen

We propose a new topological characterization of RNA secondary structures with pseudoknots based on two topological invariants. Starting from the classic arc-representation of RNA secondary structures, we consider a model that couples both…

Biomolecules · Quantitative Biology 2016-10-19 Graziano Vernizzi , Henri Orland , A. Zee

In this paper we consider the problem of RNA folding with pseudoknots. We use a graphical representation in which the secondary structures are described by planar diagrams. Pseudoknots are identified as non-planar diagrams. We analyze the…

Biomolecules · Quantitative Biology 2007-05-23 G. Vernizzi , H. Orland , A. Zee

We present a novel topological classification of RNA secondary structures with pseudoknots. It is based on the topological genus of the circular diagram associated to the RNA base-pair structure. The genus is a positive integer number,…

Biomolecules · Quantitative Biology 2007-05-23 Michael Bon , Graziano Vernizzi , Henri Orland , A. Zee

In this paper we study canonical $\gamma$-structures, a class of RNA pseudoknot structures that plays a key role in the context of polynomial time folding of RNA pseudoknot structures. A $\gamma$-structure is composed by specific building…

Combinatorics · Mathematics 2013-09-05 Hillary S. W. Han , Thomas J. X. Li , Christian M. Reidys

Background: RNA exhibits a variety of structural configurations. Here we consider a structure to be tantamount to the noncrossing Watson-Crick and \pairGU-base pairings (secondary structure) and additional cross-serial base pairs. These…

Combinatorics · Mathematics 2010-03-11 James Z. M. Gao , Linda Y. M. Li , Christian M. Reidys
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