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In this paper, we address the question of comparison between populations of trees. We study an statistical test based on the distance between empirical mean trees, as an analog of the two sample z statistic for comparing two means. Despite…

Statistics Theory · Mathematics 2007-08-14 Ana Georgina Flesia , Ricardo Fraiman

We consider the reconciliation problem, in which the task is to find a mapping of a gene tree into a species tree, so as to maximize the likelihood of such fitting, given the available data. We describe a model for the evolution of the…

Populations and Evolution · Quantitative Biology 2023-11-09 Albert C. Soewongsono , Jiahao Diao , Tristan Stark , Amanda E. Wilson , David A. Liberles , Barbara R. Holland , Malgorzata M. O'Reilly

In this paper, we give a constructive proof of the fact that the treewidth of a graph is at most its divisorial gonality. The proof gives a polynomial time algorithm to construct a tree decomposition of width at most $k$, when an effective…

Discrete Mathematics · Computer Science 2020-05-13 Hans L. Bodlaender , Josse van Dobben de Bruyn , Dion Gijswijt , Harry Smit

Tree rearrangement operations typically induce a metric on the space of phylogenetic trees. One important property of these metrics is the size of the neighbourhood, that is, the number of trees exactly one operation from a given tree. We…

Combinatorics · Mathematics 2012-02-13 Peter J. Humphries , Taoyang Wu

A wide range of models have been proposed for Graph Generative Models, necessitating effective methods to evaluate their quality. So far, most techniques use either traditional metrics based on subgraph counting, or the representations of…

Machine Learning · Statistics 2022-06-14 Hamed Shirzad , Kaveh Hassani , Danica J. Sutherland

Gene tree/species tree reconciliation is a recent decisive progress in phylo-genetic methods, accounting for the possible differences between gene histories and species histories. Reconciliation consists in explaining these differences by…

Quantitative Methods · Quantitative Biology 2017-10-05 Damir Hasic , Eric Tannier

Topological phylogenetic trees can be assigned edge weights in several natural ways, highlighting different aspects of the tree. Here the rooted triple and quartet metrizations are introduced, and applied to formulate novel fast methods of…

Populations and Evolution · Quantitative Biology 2019-05-15 John A. Rhodes

Phylogenetic networks generalize phylogenetic trees by allowing reticulate evolutionary events such as horizontal gene transfer and hybridization. Among the many subclasses of phylogenetic networks, orchard networks have attracted…

Populations and Evolution · Quantitative Biology 2026-05-20 Peng Li , Zhiwei Liu , Yangjing Long

The path-difference metric is one of the oldest and most popular distances for the comparison of phylogenetic trees, but its statistical properties are still quite unknown. In this paper we compute the expected value under the Yule model of…

Populations and Evolution · Quantitative Biology 2012-03-13 Gabriel Cardona , Arnau Mir , Francesc Rossello

We introduce a biologically natural, mathematically tractable model of random phylogenetic network to describe evolution in the presence of hybridization. One of the features of this model is that the hybridization rate of the lineages…

Probability · Mathematics 2024-02-27 François Bienvenu , Jean-Jil Duchamps

There are several interrelated notions of discrete curvature on graphs. Many approaches utilize the optimal transportation metric on its probability simplex or the distance matrix of the graph. In this survey article, we compute formulas…

Combinatorics · Mathematics 2025-11-04 Sawyer Jack Robertson

Gene trees record the combination of gene level events, such as duplication, transfer and loss, and species level events, such as speciation and extinction. Gene tree-species tree reconciliation methods model these processes by drawing gene…

Populations and Evolution · Quantitative Biology 2013-06-11 Gergely J. Szöllősi , Wojciech Rosikiewicz , Bastien Boussau , Eric Tannier , Vincent Daubin

We define, analyze, and give efficient algorithms for two kinds of distance measures for rooted and unrooted phylogenies. For rooted trees, our measures are based on the topologies the input trees induce on triplets; that is, on…

Data Structures and Algorithms · Computer Science 2009-06-30 Mukul S. Bansal , Jianrong Dong , David Fernández-Baca

Statistically consistent estimation of phylogenetic trees or gene trees is possible if pairwise sequence dissimilarities can be converted to a set of distances that are proportional to the true evolutionary distances. Susko et al. (2004)…

Populations and Evolution · Quantitative Biology 2015-04-28 Emily Jane McTavish , Mike Steel , Mark T. Holder

We study the inertia of distance matrices of weighted graphs. Our novel congruence-based proof of the inertia of weighted trees extends to a proof for the inertia of weighted unicyclic graphs whose cycle is a triangle. Partial results are…

Combinatorics · Mathematics 2023-04-26 Jeffrey Cheng , Ian Malcolm Johnson McInnis , Matthew Yee

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

Populations and Evolution · Quantitative Biology 2025-10-14 Niels Holtgrefe , Elizabeth S. Allman , Hector Baños , Leo van Iersel , Vincent Moulton , John A. Rhodes , Kristina Wicke

The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

Species tree estimation is a complex problem, due to the fact that different parts of the genome can have different evolutionary histories than the genome itself. One of the causes for this discord is incomplete lineage sorting (also called…

Populations and Evolution · Quantitative Biology 2019-04-09 Erin Molloy , Tandy Warnow

Recombination is a powerful evolutionary process that shapes the genetic diversity observed in the populations of many species. Reconstructing genealogies in the presence of recombination from sequencing data is a very challenging problem,…

Populations and Evolution · Quantitative Biology 2022-06-01 Elizabeth Hayman , Anastasia Ignatieva , Jotun Hein

Random graphs are more and more used for modeling real world networks such as evolutionary networks of proteins. For this purpose we look at two different models and analyze how properties like connectedness and degree distributions are…

Probability · Mathematics 2019-02-05 Klemens Taglieber , Uta Freiberg