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Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

Repetitions within a given genealogical tree provides some information about the degree of consanguineity of a population. They can be analyzed with techniques usually employed in statistical physics when dealing with fixed point…

Statistical Mechanics · Physics 2009-10-31 Paolo De Los Rios , Oscar Pla

We study distorted metrics on binary trees in the context of phylogenetic reconstruction. Given a binary tree $T$ on $n$ leaves with a path metric $d$, consider the pairwise distances $\{d(u,v)\}$ between leaves. It is well known that these…

Combinatorics · Mathematics 2007-05-23 Elchanan Mossel

Many models of genome rearrangement involve operations (e.g. inversions and translocations) that are self-inverse, and hence generate a group acting on the space of genomes. This gives a correspondence between genome arrangements and the…

Group Theory · Mathematics 2016-01-19 Chad Clark , Attila Egri-Nagy , Andrew R. Francis , Volker Gebhardt

Reciprocal best matches play an important role in numerous applications in computational biology, in particular as the basis of many widely used tools for orthology assessment. Nevertheless, very little is known about their mathematical…

Populations and Evolution · Quantitative Biology 2019-08-30 Manuela Geiß , Peter F. Stadler , Marc Hellmuth

Phylogenetic networks generalize phylogenetic trees by allowing the modelization of events of reticulate evolution. Among the different kinds of phylogenetic networks that have been proposed in the literature, the subclass of binary…

Data Structures and Algorithms · Computer Science 2020-07-01 Gabriel Cardona , Joan Carles Pons , Celine Scornavacca

Connected acyclic graphs (trees) are data objects that hierarchically organize categories. Collections of trees arise in a diverse variety of fields, including evolutionary biology, public health, machine learning, social sciences and…

Methodology · Statistics 2025-12-01 Maria Alejandra Valdez Cabrera , Amy D Willis , Armeen Taeb

Recent theoretical work has demonstrated that Neighbor Joining applied to concatenated DNA sequences is a statistically consistent method of species tree reconstruction. This brief note compares the accuracy of this approach to other…

Populations and Evolution · Quantitative Biology 2016-12-07 Joseph Rusinko , Matthew McPartlon

Since Darwin, species trees have been used as a simplified description of the relationships which summarize the complicated network $N$ of reality. Recent evidence of hybridization and lateral gene transfer, however, suggest that there are…

Populations and Evolution · Quantitative Biology 2016-11-17 Stephen J. Willson

Staged trees are a relatively recent class of probabilistic graphical models that extend Bayesian networks to formally and graphically account for non-symmetric patterns of dependence. Machine learning algorithms to learn them from data…

Applications · Statistics 2024-01-04 Manuele Leonelli , Gherardo Varando

In this paper, we present a flexible and probabilistic framework for tracking topological features in time-varying scalar fields using merge trees and partial optimal transport. Merge trees are topological descriptors that record the…

Computational Geometry · Computer Science 2025-08-26 Mingzhe Li , Xinyuan Yan , Lin Yan , Tom Needham , Bei Wang

Treewidth is arguably the most important structural graph parameter leading to algorithmically beneficial graph decompositions. Triggered by a strongly growing interest in temporal networks (graphs where edge sets change over time), we…

Data Structures and Algorithms · Computer Science 2020-04-29 Till Fluschnik , Hendrik Molter , Rolf Niedermeier , Malte Renken , Philipp Zschoche

Learning about the relationship between distance to landmarks and events and phenomena of interest is a multi-faceted problem, as it may require taking into account multiple dimensions, including: spatial position of landmarks, timing of…

Applications · Statistics 2024-09-11 Ines Levin

Phylogenetic inference-the derivation of a hypothesis for the common evolutionary history of a group of species- is an active area of research at the intersection of biology, computer science, mathematics, and statistics. One assumes the…

Populations and Evolution · Quantitative Biology 2016-06-21 Ruth Davidson , Joseph Rusinko , Zoe Vernon , Jing Xi

Tree reconstruction methods are often judged by their accuracy, measured by how close they get to the true tree. Yet most reconstruction methods like ML do not explicitly maximize this accuracy. To address this problem, we propose a…

Populations and Evolution · Quantitative Biology 2009-11-22 Peter Huggins , Wenbin Li , David Haws , Thomas Friedrich , Jinze Liu , Ruriko Yoshida

We study random graph models for directed acyclic graphs, an important class of networks that includes citation networks, food webs, and feed-forward neural networks among others. We propose two specific models, roughly analogous to the…

Physics and Society · Physics 2009-10-16 Brian Karrer , M. E. J. Newman

Graphs are used in almost every scientific discipline to express relations among a set of objects. Algorithms that compare graphs, and output a closeness score, or a correspondence among their nodes, are thus extremely important. Despite…

Discrete Mathematics · Computer Science 2020-11-17 Sam Safavi , José Bento

Node similarity is a fundamental problem in graph analytics. However, node similarity between nodes in different graphs (inter-graph nodes) has not received a lot of attention yet. The inter-graph node similarity is important in learning a…

Databases · Computer Science 2016-02-17 Haohan Zhu , Xianrui Meng , George Kollios

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

Populations and Evolution · Quantitative Biology 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Arboreal networks are a generalization of rooted trees, defined by keeping the tree-like structure, but dropping the requirement for a single root. Just as the class of cographs is precisely the class of undirected graphs that can be…

Combinatorics · Mathematics 2025-02-13 Guillaume E. Scholz
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