Matrix-analytic methods for the evolution of species trees, gene trees, and their reconciliation
Abstract
We consider the reconciliation problem, in which the task is to find a mapping of a gene tree into a species tree, so as to maximize the likelihood of such fitting, given the available data. We describe a model for the evolution of the species tree, a subfunctionalisation model for the evolution of the gene tree, and provide an algorithm to compute the likelihood of the reconciliation. We derive our results using the theory of matrix-analytic methods and describe efficient algorithms for the computation of a range of useful metrics. We illustrate the theory with examples and provide the physical interpretations of the discussed quantities, with a focus on the practical applications of the theory to incomplete data.
Keywords
Cite
@article{arxiv.2309.06447,
title = {Matrix-analytic methods for the evolution of species trees, gene trees, and their reconciliation},
author = {Albert C. Soewongsono and Jiahao Diao and Tristan Stark and Amanda E. Wilson and David A. Liberles and Barbara R. Holland and Malgorzata M. O'Reilly},
journal= {arXiv preprint arXiv:2309.06447},
year = {2023}
}
Comments
Corrected names of two authors (Liberles, Holland). Added further details of the contributions in the Acknowledgements