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In ecological systems heterogeneous interactions between pathogens take place simultaneously. This occurs, for instance, when two pathogens cooperate, while at the same time multiple strains of these pathogens co-circulate and compete.…

Populations and Evolution · Quantitative Biology 2025-05-05 Francesco Pinotti , Fakhteh Ghanbarnejad , Philipp Hövel , Chiara Poletto

An increasing number of control techniques are introduced to HIV infection problem to explore the options of helping clinical testing, optimizing drug treatments and to study the drug resistance situations. In such cases, complete/accurate…

Optimization and Control · Mathematics 2019-07-17 Fei Sun , Kamran Turkoglu

Multidimensional heterogeneity and endogeneity are important features of models with multiple treatments. We consider a heterogeneous coefficients model where the outcome is a linear combination of dummy treatment variables, with each…

Econometrics · Economics 2021-11-23 Whitney K. Newey , Sami Stouli

Epidemic spreading is well understood when a disease propagates around a contact graph. In a stochastic susceptible-infected-susceptible setting, spectral conditions characterise whether the disease vanishes. However, modelling human…

Social and Information Networks · Computer Science 2021-09-15 Desmond John Higham , Henry-Louis de Kergorlay

This study conducts a comparative analysis of stochastic and deterministic models to better understand the dynamics of the HIV epidemic across genders. By incorporating gender-specific transmission probabilities and treatment uptake rates,…

Populations and Evolution · Quantitative Biology 2025-01-30 Nuzhat Nuari Khan Rivu , Md Kamrujjaman , Shohel Ahmed

The SIR model with spatially inhomogeneous infection rate is studied with numerical simulations in one, two, and three dimensions, considering the case that the infection spreads inhomogeneously in densely populated regions or hot spots. We…

Medical Physics · Physics 2020-12-25 Hidetsugu Sakaguchi , Yuta Nakao

When highly active antiretroviral therapy is administered for long periods of time to HIV-1 infected patients, most patients achieve viral loads that are ``undetectable'' by standard assay (i.e., HIV-1 RNA $ < 50$ copies/ml). Yet despite…

Populations and Evolution · Quantitative Biology 2012-11-20 Laura E. Jones , Alan S. Perelson

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

Physics and Society · Physics 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco

We investigate the Susceptible-Infectious-Recovered contagion dynamics in a system of self-propelled particles with polar alignment. Using agent-based simulations, we analyze the outbreak process for different combinations of the spatial…

Adaptation and Self-Organizing Systems · Physics 2021-06-16 Yinong Zhao , Cristián Huepe , Pawel Romanczuk

In this study, we consider three dark energy models in which $\Lambda$ is not constant, but has a dynamic nature that depends on the Hubble parameter $H$ and/or its time derivative $\dot{H}$. We analyze the generalized running vacuum model,…

Cosmology and Nongalactic Astrophysics · Physics 2022-01-05 Christine R. Farrugia , Joseph Sultana , Jurgen Mifsud

HIV is a retrovirus that attacks the human immune system and can lead to death without proper treatment. In collaboration with the WHO and Wits University, we study how to improve the efficiency of HIV testing with the goal of eventual…

Social and Information Networks · Computer Science 2026-01-26 Akseli Kangaslahti , Davin Choo , Lingkai Kong , Milind Tambe , Alastair van Heerden , Cheryl Johnson

The resurgence of vector-borne diseases is an increasing public health concern, and there is a need for a better understanding of their dynamics. For a number of diseases, e.g. dengue and chikungunya, this resurgence occurs mostly in urban…

Populations and Evolution · Quantitative Biology 2017-04-14 Abderrahman Iggidr , Gauthier Sallet , Max O. Souza

How coperation between self-interested individuals evolve is a crucial problem, both in biology and in social sciences, that is far from being well understood. Evolutionary game theory is a useful approach to this issue. The simplest model…

Cellular Automata and Lattice Gases · Physics 2007-12-21 H. Fort

We study an individual-based stochastic SIR epidemic model with infection-age dependent infectivity on a large random graph, capturing individual heterogeneity and non-homogeneous connectivity. Each individual is associated with particular…

Probability · Mathematics 2026-02-11 Guodong Pang , Étienne Pardoux , Aurélien Velleret

Infectious diseases outbreaks are often characterized by a spatial component induced by hosts' distribution, mobility, and interactions. Spatial models that incorporate hosts' movements are being used to describe these processes, to…

Physics and Society · Physics 2012-07-20 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

We investigate a nonlocal single-species reaction-diffusion-advection model that integrates the spatial memory of previously visited locations and nonlocal detection in space, resulting in a coupled PDE-ODE system reflective of several…

Analysis of PDEs · Mathematics 2023-10-05 Di Liu , Yurij Salmaniw , Jonathan R. Potts , Junping Shi , Hao Wang

An increasing amount of geo-referenced mobile phone data enables the identification of behavioral patterns, habits and movements of people. With this data, we can extract the knowledge potentially useful for many applications including the…

Applications · Statistics 2015-03-24 Sanja Brdar , Katarina Gavric , Dubravko Culibrk , Vladimir Crnojevic

Dynamic network data analysis requires joint modelling individual snapshots and time dynamics. This paper proposes a new two-way heterogeneity model towards this goal. The new model equips each node of the network with two heterogeneity…

Methodology · Statistics 2024-04-15 Binyan Jiang , Chenlei Leng , Ting Yan , Qiwei Yao , Xinyang Yu

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee