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Motivation: Modern genomics laboratories generate massive volumes of sequencing data, often resulting in significant storage costs. Genomics storage consists of duplicate files, temporary processing files, and redundant intermediate data.…

Genomics · Quantitative Biology 2025-11-27 Margot Celerie , Andrew Oldfield , William Ritchie

The field of single-cell biology is growing rapidly and is generating large amounts of data from a variety of species, disease conditions, tissues, and organs. Coordinated efforts such as CZI CELLxGENE, HuBMAP, Broad Institute Single Cell…

Scientific applications in HPC environment are more com-plex and more data-intensive nowadays. Scientists usually rely on workflow system to manage the complexity: simply define multiple processing steps into a single script and let the…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-17 Dong Dai , Robert Ross , Dounia Khaldi , Yonghong Yan , Matthieu Dorier , Neda Tavakoli , Yong Chen

In our former works we have made serious efforts to improve the performance of medical image analysis methods with using ensemble-based systems. In this paper, we present a novel hardware-based solution for the efficient adoption of our…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Laszlo Kovacs , Roland Kovacs , Andras Hajdu

The high-performance computing (HPC) community has recently seen a substantial diversification of hardware platforms and their associated programming models. From traditional multicore processors to highly specialized accelerators, vendors…

Plasma Physics · Physics 2024-11-11 Josef Ruzicka , Christian Asch , Esteban Meneses , Markus Rampp , Erwin Laure

Image analysis tasks in computational pathology are commonly solved using convolutional neural networks (CNNs). The selection of a suitable CNN architecture and hyperparameters is usually done through exploratory iterative optimization,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-11 Lars Ole Schwen , Daniela Schacherer , Christian Geißler , André Homeyer

Applications to process seismic data employ scalable parallel systems to produce timely results. To fully exploit emerging processor architectures, application will need to employ threaded parallelism within a node and message passing…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-03-15 Sri Raj Paul , John Mellor-Crummey , Mauricio Araya-Polo , Detlef Hohl

High-level synthesis (HLS) tools have brought FPGA development into the mainstream, by allowing programmers to design architectures using familiar languages such as C, C++, and OpenCL. While the move to these languages has brought…

Hardware Architecture · Computer Science 2019-10-11 Johannes de Fine Licht , Torsten Hoefler

In this paper, we introduce HamilToniQ, an open-source, and application-oriented benchmarking toolkit for the comprehensive evaluation of Quantum Processing Units (QPUs). Designed to navigate the complexities of quantum computations,…

Quantum Physics · Physics 2024-04-23 Xiaotian Xu , Kuan-Cheng Chen , Robert Wille

The amount of remote sensing data available to applications is constantly growing due to the rise of very-high-resolution sensors and short repeat cycle satellites. Consequently, tackling computational complexity in Earth Observation…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-09-29 Remi Cresson

Containers are an emerging technology that hold promise for improving productivity and code portability in scientific computing. We examine Linux container technology for the distribution of a non-trivial scientific computing software stack…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-06-19 Jack S. Hale , Lizao Li , Chris N. Richardson , Garth N. Wells

Embarrassingly parallel problems can be split in parts that are characterized by a really low (or sometime absent) exchange of information during their computation in parallel. As a consequence they can be effectively computed in parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-06-26 Patrizio Dazzi

High-performance computing platforms such as supercomputers have traditionally been designed to meet the compute demands of scientific applications. Consequently, they have been architected as producers and not consumers of data. The Apache…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-02-02 Andre Luckow , Ioannis Paraskevakos , George Chantzialexiou , Shantenu Jha

When you first heard people speak of Piles of PCs, the first thing that came to mind may have been a cluttered computer room with processors, monitors, and snarls of cables all around. Collections of computers have undoubtedly become more…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 Mark Baker , Rajkumar Buyya , Dan Hyde

Most AI projects start with a Python notebook running on a single laptop; however, one usually needs to go through a mountain of pains to scale it to handle larger dataset (for both experimentation and production deployment). These usually…

We present a newly developed software package which implements a wide range of routines frequently used in Weak Gravitational Lensing (WL). With the continuously increasing size of the WL scientific community we feel that easy to use…

Cosmology and Nongalactic Astrophysics · Physics 2016-11-18 Andrea Petri

Applications integrating analysis components require a programmable interface which defines statistical operations independently of any programming language. By separating concerns of scientific computing from application and implementation…

Computation · Statistics 2014-06-19 Jeroen Ooms

Exploiting the performance of today's processors requires intimate knowledge of the microarchitecture as well as an awareness of the ever-growing complexity in thread and cache topology. LIKWID is a set of command-line utilities that…

Distributed, Parallel, and Cluster Computing · Computer Science 2010-07-01 Jan Treibig , Georg Hager , Gerhard Wellein

We propose a hybrid machine learning architecture that simultaneously employs multiple deep learning models analyzing contextual and behavioral characteristics of Windows portable executable, producing a final prediction based on a decision…

Cryptography and Security · Computer Science 2024-10-22 Dmitrijs Trizna

Although High Performance Computing (HPC) users understand basic resource requirements such as the number of CPUs and memory limits, internal infrastructural utilization data is exclusively leveraged by cluster operators, who use it to…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-19 Abel Souza , Kristiaan Pelckmans , Johan Tordsson
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