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GitHub Copilot, an extension for the Visual Studio Code development environment powered by the large-scale language model Codex, makes automatic program synthesis available for software developers. This model has been extensively studied in…

Software Engineering · Computer Science 2021-11-16 Dominik Sobania , Martin Briesch , Franz Rothlauf

High-Performance Computing (HPC) processors are nowadays integrated Cyber-Physical Systems demanding complex and high-bandwidth closed-loop power and thermal control strategies. To efficiently satisfy real-time multi-input multi-output…

Branch is a web application that provides users with no programming with the ability to interact directly with large biomedical datasets. The interaction is mediated through a collaborative graphical user interface for building and…

Applications · Statistics 2016-05-04 Karthik Gangavarapu , Vyshakh Babji , Tobias Meißner , Andrew I. Su , Benjamin M. Good

Linux container technologies such as Docker and Singularity offer encapsulated environments for easy execution of software. In high performance computing, this is especially important for evolving and complex software stacks with…

Operating Systems · Computer Science 2022-12-15 Vanessa Sochat , Matthieu Muffato , Audrey Stott , Marco De La Pierre , Georgia Stuart

Multiple signal classification algorithm (MUSICAL) provides a super-resolution microscopy method. In the previous research, MUSICAL has enabled data-parallelism well on a desktop computer or a Linux-based server. However, the running time…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-14 Quan Do , Jon Ivar Kristiansen , Krishna Agarwal , Phuong Hoai Ha

The ability to understand how a scientific application is executed on a large HPC system is of great importance in allocating resources within the HPC data center. In this paper, we describe how we used system performance data to identify:…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-15 David Brayford , Christoph Bernau , Wolfram Hesse , Carla Guillen

BioImageLoader (BIL) is a python library that handles bioimage datasets for machine learning applications, easing simple workflows and enabling complex ones. BIL attempts to wrap the numerous and varied bioimages datasets in unified…

Quantitative Methods · Quantitative Biology 2023-03-07 Seongbin Lim , Xingjian Zhang , Emmanuel Beaurepaire , Anatole Chessel

Diversity represents a key concept in ecology, and there are various methods of assessing it. The multitude of diversity indices are quite puzzling and sometimes difficult to compute for a large volume of data. This paper promotes a…

Quantitative Methods · Quantitative Biology 2016-02-15 Ciprian Palaghianu

Tomographic imaging has benefited from advances in X-ray sources, detectors and optics to enable novel observations in science, engineering and medicine. These advances have come with a dramatic increase of input data in the form of faster…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-25 Stefano Marchesini , Anuradha Trivedi , Pablo Enfedaque , Talita Perciano , Dilworth Parkinson

Modern HPC file systems can contain billions of files and hundreds of petabytes of data, making even simple questions increasingly intractable to answer. Traditional file system utilities such as find and du fail to scale to these sizes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-14 Haochen Pan , Ryan Chard , Song Young Oh , Maxime Gonthier , Valérie Hayot-Sasson , Geoffrey Lentner , Joe Bottigliero , Rachana Ananthakrishnan , Kyle Chard , Ian Foster

For scientific software, especially those used for large-scale simulations, achieving good performance and efficiently using the available hardware resources is essential. It is important to regularly perform benchmarks to ensure the…

The emergence of large-scale AI models, like GPT-4, has significantly impacted academia and industry, driving the demand for high-performance computing (HPC) to accelerate workloads. To address this, we present HPCClusterScape, a…

Human-Computer Interaction · Computer Science 2023-12-22 Heungseok Park , Aeree Cho , Hyojun Jeon , Hayoung Lee , Youngil Yang , Sungjae Lee , Heungsub Lee , Jaegul Choo

In this chapter, we describe the Parallel Sparse Computation Toolkit (PSCToolkit), a suite of libraries for solving large-scale linear algebra problems in an HPC environment. In particular, we focus on the tools provided for the solution of…

Numerical Analysis · Mathematics 2025-01-09 Pasqua D'Ambra , Fabio Durastante , Salvatore Filippone

Computer-based scientific experiments are becoming increasingly data-intensive, necessitating the use of High-Performance Computing (HPC) clusters to handle large scientific workflows. These workflows result in complex data and control…

Databases · Computer Science 2025-02-17 Zahra Sadeghibogar , Alessandro Berti , Marco Pegoraro , Wil M. P. van der Aalst

Curated databases have become important sources of information across scientific disciplines, and due to the manual work of experts, often become important reference works. Features such as provenance tracking, archiving, and data citation…

Programming Languages · Computer Science 2021-07-20 Simon Fowler , Simon D. Harding , Joanna Sharman , James Cheney

There are many science applications that require scalable task-level parallelism and support for flexible execution and coupling of ensembles of simulations. Most high-performance system software and middleware, however, are designed to…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-06-29 Vivekanandan Balasubramanian , Antons Treikalis , Ole Weidner , Shantenu Jha

With the increasing amount of data and use of computation in science, software has become an important component in many different domains. Computing is now being used more often and in more aspects of scientific work including data…

Software Engineering · Computer Science 2013-12-17 David Koop , Juliana Freire , Claudio T. Silva

Interactive high-performance computing is doubtlessly beneficial for many computational science and engineering applications whenever simulation results should be visually processed in real time, i.e. during the computation process.…

Computational Engineering, Finance, and Science · Computer Science 2018-07-03 Ralf-Peter Mundani , Jérôme Frisch , Vasco Varduhn , Ernst Rank

Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…

Quantitative Methods · Quantitative Biology 2025-11-03 Surajit Das , Pavel Zun

Bioinformatics web servers are critical resources in modern biomedical research, facilitating interactive exploration of datasets through custom-built interfaces with rich visualization capabilities. However, this human-centric design…

Other Quantitative Biology · Quantitative Biology 2026-02-25 Matthias Flotho , Ian Ferenc Diks , Philipp Flotho , Leidy-Alejandra G. Molano , Pascal Hirsch , Andreas Keller